NMR常見溶劑峰和水峰

1、溶劑1H化學位移6（精細多重峰數(shù)）JHD/Hz13C化學位移6（精細多重峰數(shù)）JCD/HzNMRS劑中殘余H2O或HOD勺質(zhì)子化學移相對密度（20C）熔占八、/C沸點/C丙酮一d62.05(5)2.2206.68(13)29.920.919.42.80.87-9457氯仿-d7.27(1)77.23(3)32.01.51.50-6462重水4.80(DSS)4.81(TSP)4.81.113.8101.4N,N-二甲基甲酰胺-d78.03(1)2.92(5)2.75(51.91.9163.15(3)34.8929.76(729.421.021.13.51.04-61153二甲基業(yè)碉-d62.5

2、0(5)1.939.51(7)21.03.31.18181189甲醇-d44.87(1)3.31(5)1.749.15(7)21.44.90.89-9865注：JHD為溶劑本身的其他1H對與之相對應(yīng)的1H之間的耦合常數(shù)，JCD為溶劑本身1H對13C的耦合常數(shù)，H2Offi交換了D的HODk的1H產(chǎn)生的即水峰的化學位移氯仿：小、中小、中等極性DMSO芳香系統(tǒng)（日光下自然顯色、紫外熒光）。對于酚羥基能夠出峰。芳香化合物還是芳香花，都為首選叱噬：極性大的，特別是皂花對低、中極性的樣品，最常采用笊代氯仿作溶劑，因其價格遠低于其它笊代試劑。極性大的化合物可采用笊代丙酮、重水等。針對一些特殊的樣品，可采用

3、相應(yīng)的笊代試劑：如笊代苯（用于芳香化合物、芳香高聚物）、笊代二甲基亞碉（用于某些在一般溶劑中難溶的物質(zhì)）、笊代叱噬（用于難溶的酸性或芳香化合物）等。丙酮：中等極性甲醇：極性大氯仿一甲醇：石：乙5;1小極性石：丙2:11:1中等極性氯仿：甲醇6:1極性以上含有一個糖2:1含有兩個糖含有糖的三菇皂花：一般用叱呢常見溶劑的化學位移常見溶劑的1H在不同笊代溶劑中的化學位移值CDC13(CD3)2CO(CD3)2SOC6D6CD3CNCD3ODD2O7.262.052.507.161.943.314.791.562.843.330.402.134.874.797.268.028.326.157.587.

4、902.172.092.091.552.082.152.222.622.522.541.682.502.652.717.367.367.377.157.377.332.102.052.071.551.962.032.06sOH,s3.491.093.313.123.164.013.073.282.163.343.34),mCH(3),mCH(4),m8.627.297.688.587.357.768.587.397.798.536.666.988.577.337.738.537.447.858.527.457.sCH2,qCH3,t2.054.121.261.974.051.201.994.0

5、31.171.653.890.921.974.061.202.014.091.242.074.141.5.305.635.764.275.445.49tCH2,m0.881.260.881.280.861.250.891.240.891.280.901.29tCH2,q1.253.721.123.571.063.440.963.341.123.541.193.601.173.65常見溶劑的化學位移常見溶劑的13C在不同笊代溶劑中的化學位移值CO(CD3)2SOC6D6CD3CNCD3ODJ29.8439.52128.061.32118.2649.00-79.1677.7979.1779.443

6、0.60206.3130.56204.4330.14207.4330.91209.6730.67z40.4540.0341.3140.45VV128.30128.62129.32129.341.12117.911.03116.020.20118.261.79118.060.85148.5949.9749.9049.864124.57136.56149.58123.84136.05150.27123.58135.28150.76127.76136.89150.07125.53138.35170.9660.5614.5020.68170.3159.7414.4020.56170.4460.2114

7、.1921.16171.6860.9814.5420.88172.8961.5014.4954.8453.4655.3254.783.2832.3013.8822.0530.9514.3223.0431.9614.4323.4032.3614.4523.6832.73核磁知識(NMR)一：樣品量的選擇氫譜，氟譜，碳譜至少需要5mg.1H-1HCOSY,1H-1HNOESY,1H-13CHMBC,1H-13CHSQ(C5要10-15mg.碳譜需要30mg.二：如何選擇笊代溶劑常用笊代溶齊I：CDC13,DMSO,D2O,CD3OD.特殊笊代溶齊：CD3COCD3,C6D6,CD3CN極性較大的化合物可以選擇用D2O或CD3OD如果想要觀察活潑氫切記不能選擇D2O?口CD3ODCDC13為人民幣2-3元，D2O為人民幣