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1、= 臭氧大自血療法介紹及開展?fàn)顩rIntroduction of Ozone Major Autohemotherapy and Its Development一、 國外開展的情況 Development Condition Abroad臭氧作為一種新興的治療手段在歐美已經(jīng)越來越多的被醫(yī)生們引起重視,在德國、西班牙醫(yī)生們采用臭氧自血回輸療法治療急性期中風(fēng)患者,使患者致殘率大大降低。在意大利許多醫(yī)院和醫(yī)生們用于急性椎間盤突出的治療,取得了意想不到的效果。在古巴、俄羅斯醫(yī)生們用臭氧水、臭氧油治療燒、燙傷、糖尿病足,都獲得巨大成功。世界臭氧協(xié)會、歐洲臭氧協(xié)會以及各個國家的臭氧協(xié)會紛紛成立,世界臭氧協(xié)會
2、分會中國臭氧協(xié)會于2008年9月5日成立。中國臭氧協(xié)會主席由南方醫(yī)科大學(xué)附屬南方醫(yī)院何曉峰教授擔(dān)任,與臭氧相關(guān)的學(xué)科,康復(fù)科、骨科、神經(jīng)內(nèi)科、傳染科、燒傷科、皮膚科的專家教授參與此次大會,討論交流這種新興的十分有醫(yī)學(xué)價值的診療手段。As a newly emerging treatment method, medical ozone therapy has been more and more brought to a forefront by doctors in Europe and America. Ozone auto blood transfusion therapy is adop
3、ted in treatment of acute phase stroke by doctors in Germany and Spain, which largely decreases patients disability rate. Many hospitals and doctors in Italy adopt ozone therapy in treating acute protrusion of intervertebral disc and it has achieved unexpected good results. In Cuba and Russia, docto
4、rs has achieved great success in burn and diabetic foot treatment with ozonized water and ozonized oil. International Ozone Association (IOA), European Ozone Association as well as other ozone associations in different countries are gradually established. The China Ozone Association, branch of Inter
5、national Ozone Association, is set up in Sept 5th, 2008. Directed by Professor Xiaofeng He from Nanfang Hospital, China Ozone Association attracts experts and professors from ozone application related departments, such as rehabilitation, orthopedics, neurology, infectious disease, burn, dermatology.
6、 This rising treatment is of great medical value.在這而后,三氧醫(yī)學(xué)逐步從單一治療椎間盤突出癥發(fā)展到治療骨科、肝病科、心腦血管科、燙傷科、糖尿病內(nèi)分泌科、腫瘤科等臨床科室的應(yīng)用,三氧治療也從微創(chuàng)介入向三氧大自血治療的全面發(fā)展,中國科學(xué)院北京轉(zhuǎn)化研究院(航空總醫(yī)院)的安建雄教授在三氧自體血的規(guī)范化治療做出了重要貢獻。在國內(nèi)三氧學(xué)術(shù)界逐漸形成了“南有何曉峰、北有安建雄”的格局。Thereafter, the application of ozone therapy has gradually developed from solely treatme
7、nt of intervertebral disc protrusion to clinical treatments in departments of orthopaedics, hepatopathy, cardiovascular, burn, diabetes, endocrinology as well as oncology. Ozone therapy has developed from interventional therapy to major autohemotherapy. In the aspect of standardized treatment of ozo
8、ne autohemotherapy, professor Jianxiong AN from Aviation General Hospital of China Medical University, Beijing Institute of Translational Medicine, Chinese Academy of Sciences, makes great contribution. A well-known pattern of “Xiaofeng HE from South, Jianxiong AN” is gradually formed in China ozone
9、 academic world.二、醫(yī)用價值 Medical Value臭氧自血回輸及其它療法可應(yīng)用于:Ozone autohemotherapy and other therapies are applicable in:1 腦中風(fēng)。包括出血性腦中風(fēng)和缺血性腦中風(fēng)。通過治療能明顯改善患者急性期腦水腫。同以往常規(guī)的甘露醇治療相比具有時間短、見效快的特點。同樣也可用于腦膜炎、周圍神經(jīng)病。另外,對于康復(fù)期的患者可以非常好的改善其肢體功能,提高患者的生活質(zhì)量。Cerebral apoplexy: hemorrhagic stroke and ischemic stroke.Acute phase o
10、f cerebral edema can be obviously improved through treatment. Compare with regular mannitol treatment, the ozone therapy is efficient within short time. This treatment can also be applied in treatment of meningitis and peripheral neuropathy. Besides, the ozone therapy can improve limb functions and
11、life quality for the patients who are in rehabilitation.2 高脂血癥。國內(nèi)外觀察結(jié)果顯示,治療顯效時間和有效率均明顯優(yōu)于他汀類藥物,且沒有任何副作用。Hyperlipidaemia (HLP)According to observations from domestic and abroad, the treatment effectual time and efficiency are obviously better than statins without any side effects.3 糖尿病??梢詼p少降糖藥物治療,對于糖尿
12、病引起的眼病、糖尿病足有很好的療效。Diabetes mellitusOzone therapy helps reduce application of hypoglycemic agents and has good results on eye diseases and diabetic foot caused by diabetes.4 肝炎病。對于病毒性肝炎的治療,療效相當(dāng)或弱優(yōu)于干擾素、拉米夫定等抗病毒藥物,但沒有抗病毒藥物的副作用,且費用較低。對急性肝炎的臨床治療,臭氧有好的退黃疸、降低轉(zhuǎn)氨酶作用。對于酒精性肝炎、藥物肝炎等均可有明顯的療效。HepatitisThe therape
13、utic effects of viral hepatitis equals to or slightly better than antiviral drugs such as interferon and lamivudine without any side effects. The ozone treatment is cost effective. In clinical treatment of acute hepatitis, the ozone therapy has a good curative effect in jaundice and aminotransferase
14、 reducing. Whats more, the curative result in alcoholic hepatitis and drug hepatitis treatment is clear. 5 腦外科手術(shù)腦水腫,療效顯著。Effective treatment in brain surgery of cerebral edema6 外科手術(shù)創(chuàng)傷部位。用臭氧水進行常規(guī)沖洗能明顯促進刀口愈合。最令人可喜的是,傷口留下的疤痕非常輕。Surgical traumaRegular washing with ozonized water can clearly promote the
15、healing of the wound. What is exciting is the left scar is not obvious. 7 疼痛介入科。應(yīng)用介入方式采取點位直接療法治療腰間盤、類風(fēng)濕性關(guān)節(jié)炎、帶狀皰疹技術(shù)已經(jīng)非常成熟并取得了非常好的療效,很多醫(yī)院專家老師專程去南方醫(yī)科大學(xué)附屬南方醫(yī)院及首都醫(yī)科大學(xué)附屬宣武醫(yī)院學(xué)習(xí)和交流這項技術(shù)。Pain and Intervention Therapy Department Direct point treatment technology is adopted in treating lumbar disc herniation, r
16、heumatoid arthritis and herpes zoster. Many medical school experts pay a special visit to Nanfang Hospital and Xuanwu Hospital for study and technology exchanges.8 皮膚科。應(yīng)用臭氧自血回輸療法和臭氧水沖洗對例如帶狀皰疹、濕疹和一些真菌感染有奇效。Dermatological DepartmentWashing the skin infected by herpes zoster, eczema or fungus with ozon
17、ized water or ozone autohemotherapy has a miraculous effect.9 腫瘤科。由于臭氧能誘導(dǎo)人體產(chǎn)生多種細胞因子,如腫瘤壞死因子等,所以國外很多醫(yī)療機構(gòu)將臭氧治療作為抗腫瘤的一種輔助療法,減輕放化療患者的疼痛感,提升患者自身免疫力,并取得可喜效果。Oncology DepartmentOzone therapy serves as an adjuvant treatment in antineoplastic therapy to reduce patients pain feeling and improve their immunity
18、 in many foreign medical institutes since the ozone induces human body to produce multiple cytokines, such as tumor necrosis factor.另外,目前國際上已經(jīng)承認(rèn)的一種新的疾病叫做慢性疲勞綜合癥,簡稱CFS。白領(lǐng)階層、相關(guān)工作人員、家庭主婦多發(fā)。目前唯一有效的辦法即是臭氧自血回輸療法。病人經(jīng)過一個療程(10次)的治療,癥狀消失,效果非常明顯。In addition, a new disease, which is called Chronic Fatigue Syndr
19、ome (CFS), is acknowledged in the world. It mostly occurs to white-collars, office workers and housewives. At present, the only effective way for CFS is Ozone Autohemotherapy. After a courses treatment (10 times), the symptoms disappear with clear effects. 三、臭氧大自血療法簡介 Brief Introduction of Ozone Aut
20、ohemotherapy 什么是臭氧大自血療法 What is Ozone Autohemotherapy?臭氧大自血療法療法是將50-150ml的自體血與適量抗凝劑和等量的治療濃度的臭氧混合再回輸入體內(nèi)(整個過程大約需時8-10min),從而產(chǎn)生治療作用的臭氧治療方法。Ozone Autohemotherapy refers to a treatment method that combines 50-150ml blood drawn from human body with equivalent ozone in therapeutic concentration and appropr
21、iate amount anticoagulant, and transfusing into human body (the whole process takes 8-10 mins). 臭氧的治療作用Therapeutic Effects of Ozone therapy1.強氧化作用 Strong oxidation2.促進血液循環(huán)作用 Promote blood circulation3.促進含氧血紅蛋白向組織釋放氧氣從而提高氧代謝水平 Accelerate hemoglobin release oxygen into tissues and improve oxygen metab
22、olism. 4.免疫刺激及平衡作用 Immunostimulation and balancing effect5.廣譜抗菌作用 Broad-spectrum antibacterial6.清除自由基作用 Free radicals eradicating 7.清除腫瘤細胞 Eliminating tumor cells(一)臭氧大自血療法適應(yīng)癥 Indications for Ozone Autohemotherapy1、慢性缺血性疾病 Chronic ischemic disease動脈循環(huán)性疾病主要由于動脈粥樣硬化引起的各個器官的疾病。Arterial circulation diso
23、rders: various organic disease caused by atherosclerosis. 腦動脈粥樣硬化引起的缺血性腦?。篢IA、腦梗塞、腦栓塞Ischemic encephalopathy caused by cerebral atherosclerosis: TIA, cerebral infarction, brain embolism.心臟粥樣硬化引起的缺血性心臟?。汗谛牟?、心絞痛、心梗、心肌供血不足等。Ischemic heart disease caused by atherosclerotic heart: coronary heart disease,
24、 angina, myocardial infarction, myocardial ischemia.外周動脈粥樣硬化引起的缺血性外周血管疾病:下肢動脈硬化閉鎖癥、血管性間歇性跛行等。Ischemic peripheral vascular disease caused by peripheral atherosclerotic lesions: lower limb arteriosclerosis locked-in syndrome and intermittent claudication.腎動脈粥樣硬化引起的缺血性腎臟疾?。豪^發(fā)性高血壓、腎功能減退。Ischemic renal d
25、isease caused by atherosclerotic renal artery stenosis: secondary hypertension, renal hypofunction.腸系膜動脈粥樣硬化引起的:腸道功能減退繼發(fā)的各種疾病。Secondary diseases of intestinal function decline caused by mesenteric arteries2、急、慢性感染性疾病 Acute and chronic infectious disease 對于抗生素或化療耐藥細菌、病毒、真菌。甚至寄生蟲感染,如:梨形鞭毛蟲病、隱孢子蟲病,在古巴醫(yī)
26、生用臭氧油進行治療。Antibiotics and chemotherapy drug resistant bacteria, virus and fungus, parasitic infection, such as giardiasis and cryptosporidiosis are treated by Cuban doctors with ozonized oil.3、緊急情況,如在大面積創(chuàng)傷、燒傷、急性腹膜炎、毒血癥之后造成的多器官功能衰竭和死亡。聯(lián)合最好的傳統(tǒng)治療和一天3至4次的臭氧大自體血療法可以避免或降低代謝損傷的惡化,降低死亡率。另外,等待器官的病人可以在手術(shù)前在6至1
27、5天之間進行6至8次的臭氧大/小自體血療法可以提高對于感染的抵抗力和改善免疫抑制(因為麻醉或外科手術(shù))。同時可以減低器官移植后的缺血再灌流損傷。其他的一般手術(shù)也可以將臭氧治療作為手術(shù)前的準(zhǔn)備型治療。 Ozone therapy can be applied in emergency circumstances, such as multiple organ failure and death caused by large area of trauma, burn, acute peritonitis, toxemias. Combining the ozone autohemotherapy
28、 for 3-4 times a day with traditional therapy could avoid or reduce the deterioration of metabolism and decrease the death rate. Whats more, patients who are waiting for organs transplant can take 6 to 8 times micro or macro ozone authohemotherapy in 6 to 15 days before operation, so as to increase
29、immunity to the infection and improve immunosuppression (caused by anesthesia or surgery). Ischemia and reperfusion injury after the organ transplantation can be reduced. Ozone therapy can also be used in other general surgery for preoperative treatment.4、骨髓炎、膿胸、腹膜炎、膿瘡、褥瘡、慢性潰瘍、糖尿病足、燒傷、感染性傷口、念珠菌病、甲癬,
30、以上疾病經(jīng)常伴有抗生素耐藥細菌。如耐二甲氧基苯青霉素金色葡萄球菌,抗生素對于感染區(qū)域缺乏貫穿,和許多發(fā)生在許多發(fā)達國家的死亡病例都有聯(lián)系。在這樣病例,臭氧化的自體血回輸療法和局部使用臭氧化橄欖油或葵花籽油起到快速的抗菌作用,并且令人難以置信的加快傷口愈合。臭氧作為一種非常不穩(wěn)定的氣體可以被不飽和脂肪植物油化合為一種穩(wěn)定的臭氧化物。當(dāng)臭氧化油被涂在傷口創(chuàng)面的滲出液上,臭氧化油與生物分子反應(yīng),生成并釋放穩(wěn)定的過氧化氫。消毒作用和改善的氧化作用可以加速疤痕的形成。一般的傳統(tǒng)的藥膏經(jīng)過會含有無用的抗生素和生長因子。臭氧化油一旦被人們知道、使用,必將對數(shù)以百萬的患者起到極大的治療作用。The disea
31、ses, such as osteomyelitis, empyema, peritonitis, fester, pressure ulcer, chronic ulcer, diabetic foot, burn, infectious wound, candidiasis, onychomycosis, are often accompanied with antibiotics drug resistance bacteria, such as resistance to dimethoxy benzene penicillium staphylococcus aureus. The
32、antibiotics cannot run through the infected areas, which is connected to the death case happened in many developed countries. In cases like this, ozonized autohemotherapy and partly usage of ozonized olive oil or sunflower seed oil can receive rapid antibacterial effect and promote wound healing. As
33、 a very unstable gas, ozone can be chemically combined into a stable ozonide by unsaturated fat vegetable oil. When applied onto the wound surface, ozonized oil reacts with biomolecules and produces and releases stable hydrogen peroxide. The disinfection and improved oxidation effect can accelerate
34、scar formation. Traditional unguent contains useless antibiotics and growth factors. Once the ozonized oil is known and used, it will bring great treatment effects for millions of patients.5、皰疹病毒感染(HHVI和II)、帶狀皰疹、乳頭瘤病毒感染。使用肌肉內(nèi)注射的小自體血臭氧療法,作為一種字體疫苗,同時結(jié)合臭氧油的局部應(yīng)用對于預(yù)防皰疹的復(fù)發(fā)非常有作用。這種方法,特別是當(dāng)聯(lián)合使用阿昔洛維時,可以治愈絕大部分
35、的皰疹感染病人。同時對于減低帶狀皰疹感染和感染之后的神經(jīng)痛也有非常好的效果。 Herpes virus infection (HHV I and II), herpes zoster, infection of papovavirusAs an auto vaccine, combined with partly use of ozonized oil, macro ozone autohemotherapy with muscle injection is very effective in prevention of herpes recurrence. If it is used tog
36、ether with acyclovir, most of the herpes infected patients can be healed. Besides, it can also help reduce varicella-zoster virus infection and effective in lightening neuralgia.6、慢性肝炎和艾滋病感染Chronic hepatitis and AIDS infection7、自身免疫性疾?。ㄍ达L(fēng)、多發(fā)性硬化、類風(fēng)濕性關(guān)節(jié)炎、克隆?。W泽w血療法是非常令人鼓舞的。Autoimmune disease (gout, mu
37、ltiple sclerosis, rheumatoid arthritis, Crohns disease)Autohemotherapy is very inspiring. 8、退行性疾病。自體血療法可以改善老年性癡呆早期的患者。Degenerative diseaseAutohemotherapy could help improve early stage Alzheimer disease.9、肺部疾?。ǚ螝饽[、哮喘、COPD、急性呼吸窘迫綜合征)。Pulmonary disease (pulmonary emphysema, asthma, COPD, acute respira
38、tory distress syndrome) 10、對于COPD的治療原理如下:A、血液回輸,脂質(zhì)氧化物可以作用內(nèi)皮細胞表面,提高前列腺環(huán)素和NO的釋放,而內(nèi)皮縮血管肽I的釋放被抑制。NO和亞硝基硫醇的釋放促進血管舒張,而陰離子超氧化物的釋放會造成血管緊縮,并且對血小板和內(nèi)皮細胞產(chǎn)生負(fù)面影響;B、缺血組織氧輸送的增強、抗氧化酶的加強、血紅素加氧酶I中和慢性氧化應(yīng)激。C、對于免疫系統(tǒng)刺激可以控制慢性肺部感染。通過臭氧治療COPD可以達到良好的效果,包括改善呼吸系數(shù)和步行試驗。The treatment principle of CODP: A. Through the treatment, l
39、ipid peroxide acts on the surface of endotheliocyte and increase the releasing of prostacyclin and NO, thus the releasing of endothelin-1 is restrained. The producing of NO and S-nitrosothiols will promote vasodilatation while the releasing of anionic superoxide will lead to vasoconstriction and hav
40、e a negative impact on platelets and endothelial cells.B. Ischemic tissues oxygen transportation and antioxidant enzyme ability will be strengthened; haem oxygenase I neutralize chronic oxidative stress.C. Stimulation on immune system helps control chronic pulmonary infection. Ozone treatment for CO
41、DP will achieve good results, including improve respiration coefficient and minute walking test.11、期腎病被慢性氧化應(yīng)激加重,不能被傳統(tǒng)藥物控制,臭氧治療穩(wěn)定嚴(yán)重的功能障礙,提高病人的生活治療。Renal disease in late stage cannot be controlled by traditional medicine because of chronic oxidative stress. The ozone therapy stabilizes the dysfunction
42、 and improves patients life quality.12、臭氧自體血回輸療法聯(lián)合臭氧油的局部應(yīng)用被證明對于代謝綜合征非常有效,比如2型糖尿病患者的難治性慢性潰瘍。Ozone autohemotherapy, combined with ozonized oil partly applied, is proved to be effective in metabolic syndrome treatment, such as refractory chronic ulcer of type 2 diabetes patient. 13、皮膚病(牛皮癬、異位性皮炎)。Derma
43、topathya (psoriasis, atopic dermatitis)14、化療藥耐藥的轉(zhuǎn)移癌、癌性疲勞。通過臭氧治療可以提高病人的生活質(zhì)量,但是不可以阻斷癌癥的發(fā)展。另一方面,外科手術(shù)之后臭氧治療非常有效,不僅可以通過誘導(dǎo)抗氧化反應(yīng)強化細胞毒藥物的作用,而且可以降低化療藥的毒性。Metastatic cancer resisting to chemotherapeutic drugs and cancer fatigue.Although the cancerous development cannot be stopped, the ozone therapy will impro
44、ve patients life quality. On the other side, ozone therapy is very effective in postoperative treatment. This therapy can not only strengthen cytotoxic drugs effect by inducing the antioxidant response, but also decrease chemotherapeutic drugs toxicity.15、慢性疲勞綜合征和纖緯肌痛。自體血療法已經(jīng)被發(fā)現(xiàn)對于大多數(shù)的病人有效。Chronic fa
45、tigue syndrome and firbre muscle pain It is found that the macro ozone autohemotherapy is effective among most of patients(二)臭氧大自血療法禁忌癥 Contraindications of Macro Ozone Autohemotherapy甲亢、葡萄糖-6磷酸脫氫酶(G-6PD)缺乏癥、心肌梗塞發(fā)作、孕婦、血小板減少、凝血機制障礙、臭氧過敏、急性乙醇中毒、柑橘過敏等。四、醫(yī)用臭氧大自血療法發(fā)展史 Development History of Medical Ozone
46、 Autohemotherapy1.1857年德國的Werner von Siemens制造出第一種臭氧發(fā)生器。Werner von Siemens from Germany manufactures the first ozone generator in 1853.2.1870年德國C. Lender報道了第一例醫(yī)用臭氧治療性的進行血液療法。C. Lender reported the first case that adopts medical ozone to carry out hematotherapy in Germany in 1870.3.1902年,J.H.Clarke
47、39;s A Dictionary of Practical Materia Medica(實用藥物學(xué)辭典)的書中描述了很多成功應(yīng)用臭氧水治療貧血,癌癥、糖尿病、流感、嗎啡中毒、口瘡、馬錢子堿中毒、百日咳。J.H.Clarke's A Dictionary of Practical Materia Medica describes many successful cases that apply ozonized water into treatment of anemia, cancer, diabetes mellitus, influenza, morphinism, aphth
48、a, strychninism, and pertussis.4.在1911年,Dr. Noble Eberhart出版了"A Working Manual ofHigh Frequency Currents",他是Loyola大學(xué)生理治療部門的主任,他同樣應(yīng)用臭氧治療了結(jié)核病、貧血、萎黃病、百日咳、哮喘、支氣管炎、花粉熱、失眠、肺炎、糖尿病、痛風(fēng)、梅毒。Dr. Noble Eberhart published A Working Manual ofHigh Frequency Currents in 1911. As the director of therapy dep
49、artment, Dr. Eberhart treats many diseases with ozone, such as tuberculosis, anemia, chloranemia, pertussis, asthma, bronchitis, pollenosis, insomnia, pneumonia, diabetes mellitus, gout, syphilis.5.1929年,一本叫臭氧和它的治療作用在美國被出版,書中列出114種疾病以及如何應(yīng)用臭氧去進行治療,書的作者們是美國一些頂尖醫(yī)院的學(xué)術(shù)權(quán)威。The Ozone and Its Therapeutic Eff
50、ect is published in the United States in 1929. In this book, 114 diseases relevant treatment method with ozone are listed. The authors of this book are most academic authorities in top hospitals of America.6.1953年開始,德國醫(yī)生WOLF在工作應(yīng)用臭氧,撰寫醫(yī)用臭氧,并且培養(yǎng)臭氧治療的很多醫(yī)生。Since 1953, Germany doctor Wolf begins to use o
51、zone and writes Medical Ozone and cultivate many doctors using ozone treatment.7.1957年,Dr. J. Hansler取得了臭氧發(fā)生器的專利,該專利推動了德國臭氧治療學(xué)界的發(fā)展?,F(xiàn)在德國有7000名醫(yī)生在進行日常性臭氧治療工作。Dr. J. Hansler got the patent of Ozone Generator, which promote the ozone therapy development in Germany in 1957. Nowadays, there are altogether
52、 more than 7,000 doctors are carrying out ozone therapy for daily treatment in Germany.8.1982年,德國心腦血管專家DR.WASSER.GERD應(yīng)用臭氧大自體血回輸療法治療急性腦中風(fēng),取得了非常良好的效果。In 1982, Germany cardiovascular Dr. Wasser Gerd treated acute cerebral apoplexy with the application of ozone macro autohemotherapy and received very go
53、od results.9.1990年,古巴人報道了應(yīng)用臭氧治療青光眼,結(jié)膜炎,色素性視網(wǎng)膜炎。It is reported that Cuba treated glaucoma, conjunctivitis and retinitis pigmentosa with ozone in 1990.10.1992年,俄羅斯人報道了他們應(yīng)用臭氧浸潤的鹽水治療燒傷取得了驚人的療效。今天,臭氧大自血治療在許多國家已經(jīng)被承認(rèn)。包括德國、法國、意大利、俄羅斯、羅馬尼亞、捷克、波蘭、匈牙利、保加利亞、埃及、以色列、日本、古巴、墨西哥、中國、美國的五個州等。It is reported that Russia
54、n adopted saline infiltrated in ozone to treat burn wound, which achieves surprising effects. At present, the ozone macro autohemotherapy has been recognized by many countries in the world, including Germany, France, Italy, Russia, Romania, Czech, Poland, Hungary, Bulgaria, Egypt, Israel, Japan, Cub
55、a, Mexico, China and USA. 五、臭氧大自血療法國內(nèi)外應(yīng)用現(xiàn)狀及其安全性O(shè)zone Autohemotherapy Application status and Safety at Home and Abroad臭氧療法在德國應(yīng)用已有近百年的歷史,從最初局部外用治療感染性潰瘍逐漸發(fā)展到以自血療法為主的內(nèi)科治療。在德國、意大利、古巴、俄羅斯、西班牙等醫(yī)生們采用臭氧自血回輸療法治療急性期中風(fēng)患者,使患者致殘率大大降低。世界臭氧協(xié)會、歐洲臭氧協(xié)會以及各個國家的臭氧協(xié)會紛紛成立,世界臭氧協(xié)會分會中國臭氧協(xié)會于2008年9月5日成立。至2015年11月在我國除了超過幾千家醫(yī)院開展臭
56、氧治療椎間盤突出以外,已有幾百上千家醫(yī)院開展以治療慢性缺血性疾病及慢性肝炎為主的臭氧自體血回輸療法,取得了很好的社會效益和經(jīng)濟效益。It has been a hundred years for Germany applying ozone therapy, from infective ulcers treatment partly using ozone to internal medicine treatment by ozone autohemotherapy. Ozone auto blood transfusion therapy is adopted in treatment o
57、f acute phase stroke by doctors in Germany, Italy, Cuba, Russia and Spain, which largely decreases patients disability rate. International Ozone Association (IOA), European Ozone Association as well as other ozone associations in different countries are gradually established. The China Ozone Associa
58、tion, branch of International Ozone Association, is set up in Sept 5th, 2008. Till November 2015, there are thousands of hospitals in China that adopt ozone to treat intervertebral disc protrusion; hundreds of hospitals have operated ozone autohemotherapy in treatment of chronic ischemic diseases an
59、d chronic hepatitis. Exciting social effect and economic benefits are achieved.1980年,德國醫(yī)療界組織了644位專家對臭氧療法進行了回顧性研究,他們將38475位病人進行的579238次的治療結(jié)果進行了統(tǒng)計分析,發(fā)現(xiàn)只有40人次出現(xiàn)過副作用,其百分比為0.000007%,有些還是由于其他疾病的并發(fā)癥間接導(dǎo)致的。德國每年平均有700萬人次的臭氧自體血治療,但無一例死亡或嚴(yán)重并發(fā)癥,也無任何醫(yī)療糾紛。我國自2005年引進臭氧大自血療法至今,已有超過十余萬人次的治療,但無一例醫(yī)療事故或糾紛發(fā)生。這一切均表明:臭氧療法確實是最安全的。與其它治療技術(shù)不良反應(yīng)的發(fā)生
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