Atenolol-RS-Atenolol-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEAtenololCat. No.: HY-17498CAS No.: 29122-68-7Synonyms: (RS)-Atenolol分式: CHNO分量: 266.34作靶點(diǎn): Adrenergic Receptor作通路: GPCR/G Protein; Neuronal Signaling儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn)

2、 DMSO : 100 mg/mL (375.46 mM; Need ultrasonic)H2O : 8.33 mg/mL (31.28 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 3.7546 mL 18.7730 mL 37.5460 mL5 mM 0.7509 mL 3.7546 mL 7.5092 mL10 mM 0.3755 mL 1.8773 mL 3.7546 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給

3、藥式選擇適當(dāng)?shù)娜芙獍?，配制前?qǐng)先配制澄清的儲(chǔ)備液，再依次添加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請(qǐng)依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (9.39 mM); Clear solution2. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (9.39 mM); Cle

4、ar solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE3. 請(qǐng)依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (9.39 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Atenolol是選擇性1腎上腺素受體拮抗劑。戶使本產(chǎn)品發(fā)表的科研獻(xiàn) Protein Cell. 2019 Mar;10(3):178-195. Chemosphere. 2019 Mar.See more customer validations on HYPERLI

5、NK / www.MedChemEREFERENCES1. Carlberg, B., O. Samuelsson, and L.H. Lindholm, Atenolol in hypertension: is it a wise choice? Lancet, 2004. 364(9446): p. 1684-9.2. DeLima, L.G., E.D. Kharasch, and S. Butler, Successful pharmacologic treatment of massive atenolol overdose: sequentialhemodynamics and plasma atenolol concentrations. Anesthesiology, 1995. 83(1): p. 204-7.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;