Rifaximin - Bacterial 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemERifaximinCat. No.: HY-13234CAS No.: 80621-81-4分式: CHNO分量: 785.88作靶點(diǎn): Bacterial作通路: Anti-infection儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 50 mg/mL (63.62 mM)H2O : 40% PEG300 5% Tween

2、-80 45% salineSolubility: 3 mg/mL (3.82 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 3 mg/mL (3.82 mM); Suspended solution; Need ultrasonic1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE3. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 3 mg/mL (3.82 mM); Clear solut

3、ionBIOLOGICAL ACTIVITY物活性 Rifaximin(Xifaxan)服的半合成系統(tǒng)性抗菌素，來源于利福霉素SV。REFERENCES1. Cruciani F, Brigidi P, Calanni F et al. Efficacy of rifaximin vaginal tablets in treatment of bacterial vaginosis: a molecular characterizationof the vaginal microbiota. Antimicrob Agents Chemother. 2012 Aug;56(8):4062-70

4、.2. Cremonini F, Lembo A. Rifaximin for the treatment of irritable bowel syndrome. Expert Opin Pharmacother. 2012 Feb;13(3):433-40.3. Rivkin A, Gim S. Rifaximin: new therapeutic indication and future directions. Clin Ther. 2011 Jul;33(7):812-27.4. Cottreau J, Baker SF, DuPont HL, Garey KW. Rifaximin

5、: a nonsystemic rifamycin antibiotic for gastrointestinal infections. Expert RevAnti Infect Ther. 2010 Jul;8(7):747-60.5. Koo HL, DuPont HL. Rifaximin: a unique gastrointestinal-selective antibiotic for enteric diseases. Curr Opin Gastroenterol. 2010Jan;26(1):17-25.6. Ojetti V, Lauritano EC, Barbaro F et al. Rifaximin pharmacology and clinical implications. Expert Opin Drug Metab Toxicol. 2009Jun;5(6):675-82.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-379