Flunixin-meglumine - COX 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEFlunixin meglumineCat. No.: HY-B0386CAS No.: 42461-84-7分式: CHFNO分量: 491.46作靶點(diǎn): COX作通路: Immunology/Inflammation儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) H2O : 44 mg/mL (89.53 mM)* means solub

2、le, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 2.0348 mL 10.1738 mL 20.3475 mL5 mM 0.4070 mL 2.0348 mL 4.0695 mL10 mM 0.2035 mL 1.0174 mL 2.0348 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Flunixin Meglumine是COX抑制劑，具有抗炎退熱活性。IC50 & Target COX-2

3、COX-10.4 nM (IC50) 17 nM (IC50)REFERENCES1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE1. Cheng Z, et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep.Inflammation. 1998 Aug;22(4):353-66.2. Bryant, C.E., B.A. Farnfield, and H.J. J

4、anicke, Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclearfactor kappa B. Am J Vet Res, 2003. 64(2): p. 211-5.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021-537