Pyrroloquinoline-quinone-disodium-salt-PQQ-disodium-salt-DataSheet-生命科學(xué)試劑-MedChemExpress

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEPyrroloquinolinequinonedisodiumsaltCat.No.:HY-100196ACASNo.:122628-50-6Synonyms:PQQdisodiumsalt;Methoxatindisodiumsalt分?式:C??H?N?Na?O?分?量:374.17作?靶點(diǎn):EndogenousMetabolite作?通路:MetabolicEnzyme/Protease儲(chǔ)存?式:4°C,sealedstorage,awayfrommoisture*Insolvent:-80°C,6months;-20°C,1month(sealed

storage,awayfrommoisture)溶解性數(shù)據(jù)體外實(shí)驗(yàn)H2O:1.25mg/mL(3.34mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM2.6726mL13.3629mL26.7258mL5mM---------10mM---------請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month(sealedstorage,awayfrommoisture)。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥?式選擇適當(dāng)?shù)娜芙?案。以下溶解?案都請(qǐng)先按照InVitro?式配制澄的儲(chǔ)備液，再依次添加助溶劑：(為保證實(shí)驗(yàn)結(jié)果的可靠性，澄的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；體內(nèi)實(shí)驗(yàn)的?作液，建議您現(xiàn)?現(xiàn)配，當(dāng)天使?；以下溶劑前顯?的百分?指該溶劑在您配制終溶液中的體積占?；如在配制過程中出現(xiàn)沉淀、析出現(xiàn)象，可以通過加熱和/或超聲的?式助溶)1.請(qǐng)依序添加每種溶劑：0.5%CMC-Na/salinewaterSolubility:5mg/mL(13.36mM);Suspendedsolution;Needultrasonic1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEBIOLOGICALACTIVITY?物活性Pyrroloquinolinequinonedisodiumsalt氧化還原輔助因?，?種離?型氧化還原循環(huán)原醌。Pyrroloquinolinequinonedisodiumsalt最初從嗜甲細(xì)的培養(yǎng)物中分離的，也存在于哺乳動(dòng)物的組織。Pyrroloquinolinequinonedisodiumsalt哺乳動(dòng)物的必需營(yíng)養(yǎng)素，對(duì)免疫功能很重。IC50&TargetHumanEndogenousMetabolite體外研究MousepupsborntoandnursingfromPyrroloquinolinequinonedisodiumsalt-depriveddamshaveacompromisedimmuneresponseaswellasalopecia,ahunchedposture,andasusceptibilitytoaorticaneurysms[2].REFERENCES[1].MoogRS,etal.Evidenceformethoxatin(pyrroloquinolinequinone)asthecofactorinbovineplasmaamineoxidasefromresonanceRamanspectroscopy.ProcNatlAcadSciUSA.1986Nov;83(22):8435-9.[2].BishopA,etal.Methoxatin(PQQ)inguinea-pigneutrophils.FreeRadicBiolMed.1994Oct;17(4):311-20.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-8