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高二生物免疫調(diào)節(jié)(Biologyimmuneregulation)
Biologyimmuneregulationof.TxtwhentheIQofmenafter
Einstein.Beautymakesamanstop,wisdommakesamanstay.
Nothingcanbeexchangedforhealth.Thisarticleismadeup
of8023smallparcels
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Cardingofbasicknowledge
First,theimmunesystemcomposedof1.immuneorgans:bone
marrow,thymus,spleen,lymph,immuneorgans:bonemarrow,
tonsilandsoon.Knots,tonsils,etc.2..Immunecells.(1)
phagocytes.Phagocyte.Phagocytes,etc.(2)lymphocytes:T
cellsmigratetothethymusandproducelymphocytes:cells
(migratetothethymus,lymphocytesmature)andcellsmature
inthebonemarrow.Cellsmatureinthebonemarrow,matureand
mature,andBcellsmatureinthebonemarrow.3.,immuneactive
substances:antibodies,lymphfactors,lymphfactors,immune
activesubstances:lysozymeandsoon.Lysozyme,etc..
Cardingofbasicknowledge
Two.Immunesystemfunction1.defensefunction.(1)
non-specificimmunity,non-specificimmunity,thefirstline
ofDefense:composedofskinandmucousmembrane.Firstline
ofdefence:composedofskinandmucousmembranes.Thesecond
lineofDefense:secondlinesofDefense:thebodyconsistsof
bactericidalsubstancesandphagocyticcells.Andphagocytic
cells.(2)specificimmunity,third1inesofdefense,specific
immunity(thirdlinesofdefense,specificimmunity,third
linesofDefense)
Cardingofbasicknowledge
Cardingofbasicknowledge
2.monitorandremovefunctions.Monitorandremovefinecells
thatarealreadyagingordamagedbyotherfactors.Cells,as
wellascancerouscells.
Cardingofbasicknowledge
Whatarethecellsthatrecognizeantigens?Whatarethecells
thatrecognizeantigens?Thinkingandthinking-[tips]tips]
nonphagocyticcellstoidentifyspecificantigen;cell,fine
specificantigenrecognition;Tcells,BfineeffectofTcells
andmemorycellstospecificcells,effectorcellsandmemory
cellscanidentifyspecificantigenrecognition;antigen;
plasmacellscannotbeidentifiedbutantitheantibodycan
recognize.Theantibodiesproducedcanbeidentified.
Cardingofbasicknowledge
Three,1.strongimmuneimmunedisorders.(1):autoimmune
diseaseisduetotheabnormalimmunesystemautoimmunedisease:
autoimmunedisease,excessive,sensitive,sensitivereaction
andoverreaction"regardlessoftheenemywillownsubstance
asforeigeregardlessoftheenemy"regardlessoftheenemy,
werecausedbytheattack.Causes,suchassystemiclupus
erythematosus,rheumatoidarthritis.Humidarthritis.
Cardingofbasicknowledge
(2)theconceptofallergicallergicreaction:hasimmunebody,
thenagainintheconcept:havetheimmunebody,thereaction
characteristicsareaffectedbythesameantigenstimulation
stronglydissipatedrapidly,rapidonset,strongreaction,
fadefaster,whiledestructionoftissuecells,willnotdamage
(likewillbedamaged,willnotdamagethecells,damagewill
notdamagethecells)willcause,willnotcauseseriousdamage
willcausetheorganizationdoesnotcause(cause,willnot
causeseriousdamage)organizationandindividualdifferences.
Theinjuryhasobviousgenetictendencyandindividual
difference.
Cardingofbasicknowledge
2.,thedefenseistooweak.(1)forexample:AIDS,alsoknown
asacquiredimmunity,forexample:forexample,AIDS,AIDS..
(2):theetiologybyhumanimmunodeficiencyvirus(HIV)leading
causeofdiseaseinducedmainlyattacksthebody,sTcells,HIV
cellsattackthehumanbody,itcanmakethepeoplemainly
attacksthebody'simmuneabilityofbodycells,almostalllost.
Almostallofthebody'simmunefunctionwaslost.
Cardingofbasicknowledge
Four.Theapplicationofimmunology,theinventionand
applicationofvaccinesisoneofthegreatestachievementsof
modernmedicine,
Accordingtothecharacteristicofantigenandspecific
antibodycombination,combinedwiththecharacteristicsof
antibodywasdetectedbyartificialmarkersoftissueantigen,
antigendetection,organtransplantationproblemscanbe
solved,theapplicationalsorelatestoimmunology.The
solutionalsoinvolvestheapplicationofimmunology.
Corebreakthrough
First,theimmunerelatedcellscomparetheoriginand
differentiationof1.lymphocytes
Corebreakthrough
2.comparisonofvariousimmunecells
Thefunctionofprocessingandpresentationofantigen
processingandpresentationofantigensofhematopoieticstem
cells,phagocytosisofphagocyticcellsantigenantibody
antigenrecognition,hematopoieticstemcellsinboneantigen
recognition,differentiateintoBcells,plasmacells,memory
cellsinspinalcorddevelopmentidentification,antigen
presentation,identification,antigenpresentation,
differentiationofhematopoieticstemcellsinbreastTcells
intoeffectTcells,effectorcellsandmemorycells,inthe
developmentoffineglandsecretionoflymphokinescellsor
memorycellantibodysecretingplasmacellsBcellsorTmemory
celleffectsandtargetcellscombinedwithimmuneTcellsor
memorycellsormemorycelleffectorcellantigenrecognition,
antigenrecognition,differentiationintocorrespondingcells
orTcellorBcellmemorycellsorcelleffectorcellsofthe
cellorigin
Corebreakthrough
[warning]easytophagocyticcellsinsecondindustrywarning
defenseline]phagocytosisofantigen,antigenprocessing
phagocyticdefenseline,inthethirdlineofantigen
processingandpresentation,lineofantigenprocessingand
presentingantigens,alsoeliminatedfinallystillcannotdo
withoutthephagocyte-eventuallydestroystillcannotdo
withoutthespecificphagocytosisofantibodyandantigen
combination.Aspecificcombinationofantibodiesand
antigens.
Corebreakthrough
Instantapplication
1.(2010Taizhouqualityinspectionaccordingtohumanimmunity.
Taizhouqualityinspection)accordingtohumanimmunityyear,
Taizhouqualityinspectionrelatedconceptmapanswerthe
question:therelevantconceptmapanswerthequestion:
Corebreakthrough
(1)immunecellsinhumanimmunecellsderivedfrombonemarrow
derivedinthehumanbodyinbonemarrowhematopoieticstem
cells,hematopoieticstemcellsfromhematopoieticstemcells
todifferentiateintoavarietyofimmunecellmorphologyand
function,morphologyandfunctionofimmunecells,mainlydue
to..(2)notonlycanparticipateinnon-specificimmunity,but
alsocanparticipateinnon-specificimmunity,canparticipate
innon-specificimmunity,specificimmunityisthe[specific
immunity]..
Corebreakthrough
(3)thefollowingconceptswithincells,candifferentiatethe
conceptwithinthefollowingcells,thecellsintheconcept
offorceisthefollowing.Forceis.A.memorycellB.b..C.c,
D.d..(4)formsthepathwayof[c]formation:thereareways
offormation..
Corebreakthrough
Analysis:Analysis:accordingtotherelationshipbetween
immunecellscanbedetermined,B,C,aandDrespectively
representthephagocyticcells,Tcellsandplasmarespectively
representthephagocyticcells,cells,phagocyticcells,
representingtheeffectofTcells.Avarietyofimmunecells
aremadeupofcellsandeffectorcells.(1)allkindsofimmune
cellsaredifferentiatedfromhematopoieticstemcells,and
bloodstemcellsaredifferentiated.Theessenceof
differentiationistheselectiveexpressionofgenes.
Phagocytesmaybeinvolvedinnonspecificandselective
expression.(2)phagocyticcellscanparticipateininnate
immunity,withphagocytosisandeliminationofantigen;
immunitywithphagocytosisandeliminationofantigen;and
participateinspecificimmunity,withidentification,
processing,participateinspecificimmunity,hasthefunction
ofidentification,processingandpresentationofantigen.
PlasmacellsandeffectorTcells,plasmacells,Candeffector
cells,dnolongerhaveaprimaryrole.(3)plasmacellsand
effectorcellsnolongerhavetheabilitytodifferentiate;
memorycells,cellsandcells,andTcellshavetheabilityto
differentiate;
Whilememorycells,Bcellsandcellsarestimulatedbyantigen,
theycanproliferateanddifferentiate.Stimulatedbyantigen,
itcanproliferateanddifferentiate.
Corebreakthrough
Answer:geneselectiveexpressionofgeneexpression(answer:
selectiveleftcell(1)geneexpressionintheselective
implementationofthegeneticinformationincellsofdifferent
implementationdifferentinformation)(2)a(3)ABcell
phagocytosis(4)plasmacellsdirectlystimulatecellantigen
1antigendirectlystimulatethecytoplasmofBcellsthecells
producedbyTcellantigenpresentingtothecellsandthecell
antigenspresentedtoBcellsandcellstothememorycellsby
presentingantigensstimulated
Corebreakthrough
Two,specificimmunity-thethirdlineofdefenseofthehuman
body-thethirdlineofdefenseagainstthebody;sspecific
immunity-figure1.ofhumoralimmunity
Corebreakthrough
2.adiagramofcellularimmunity
Corebreakthrough
3..Thetwoimmuneprocessesbothhavetheirownuniquefunction.
Thetwoimmuneprocessesbothhavetheirownuniquefunction
andcancooperatewitheachothertoplayanimmuneeffect.They
cancooperatewitheachothertoplayanimmuneeffect.Such
as:(1)bacterialexotoxinantigenintothehumanbody,the
humanbody(bacterialexotoxinantigenintothebody,bacterial
exotoxinantigen)intothebody,simmunesystemtoproduce
specificantitoxin(antibody),theimmunesystemtoproduce
specificantitoxin(antibody),willbeeliminated,which
belongstothehumoralimmunity.Thisishumoralimmunity.(2)
forintracellularpathogens,humoralimmunityfirstactsasan
intracellularpathogen,andpreventsthespreadofpathogens
forintracellularpathogens.Usetopreventthespreadof
pathogens.Whenpathogensenterthecell,theyrequirecellular
immunitytoreleaseantigens,whichrequirecellularimmunity
toreleaseantigens,andthentakethefinalclearanceby
humoralimmunity.Thefinalclearanceofimmunity.
Corebreakthrough
Instantapplication
2.thefollowingfigureshowsthespecificimmuneprocessof
thehumanbody.Thefollowingfigureshowsthespecificimmune
processofthehumanbody.Accordingtothisdiagram,please
pointoutthecorrectoptionis().Accordingtothisdiagram,
pleasepointoutthecorrectoptionis
Corebreakthrough
A.canidentifyspecificantigenA,B,canspecifically
recognizetheantigen,andC,D,F,B.,andthefigurein
materialrelatedtothegenerationofcells.Ina,B,andC,
G,F,andC.HIV,andinvadethebody,onlyontheinhibition
ofinvasionofthehumanbody,theimmunesystem.Theinvasion
ofrays,theeffectofD.onhumanbodyonlylargedoseof
thymectomizedmiceX.largedoseofthymectomizedmice
irradiated,resultinginthelossofallspecificimmune
functionbyenteringFcellscanmakecanmaketheenergyinput
bycanmakethecellsfullyrestored
Corebreakthrough
Parse:selectB.Cellignorance.Cellfdoesnotrecognize
antigens.Cellarecognizeantigens,butnotantigens.Cells
recognizeantigens,buttheydonotrecognizeantigens.
Specificantigenisnotrecognized.WhenHIVinvadesthehuman
body,itattackspeople'sT.Afterenteringthehumanbody,it
attackspeople'scells,resultinginalmostallthelossof
immunefunction.Almostallofthemwerelost.
Corebreakthrough
Immunodeficiencydiseaseastheimmunefunctionhasbeenimmune
tothebodyandtheautoimmuneresponseinadequateorlackof
timetoreceivethesamematerialcausedbythedisease,their
tissuedisease,canbedividedintotwoconceptswhichoccur
whenstimulatedandorgandamagecausedbycongenitalimmune
deficiency:tissueinjuryordisease,injurydisease
depressiondepressionfunctionacquiredimmunedeficiency
disordersofthesameallergenagaintheantigenicstructure
andisenteringthebody,intothebody,andoftenformhuman
immunesystemcellmaterialsurfacestructuresimilartothat
ofcongenitallydeficient(incidenceadsorbedonthecell
surfaceofsimilarstructure,
(thelackofgeneticmechanismofcongenitallydeficient
antibodybindingantibodyantigenorviruswasdestroyedinthe
attack)andothertissuecellstorelease,butalsoeliminate
damagecausedbyhistamineoftenhitcellsofrheumatoid
arthritisofdigestivetract,digestivetract,respiratory
tractinflammation,rheumaticheartcongenitalthymuswasnot
forallergicreaction,skinallergy.Heartdisease,heart
disease,systemicallergicreactionsandbenignAIDSlupus
erythematosustypeproject
Three,immunedisorders
Allergicreactionautoimmunedisease
Corebreakthrough
[warning]AIDSHIViseasytoinvadethefalsewarningis]
invadesthehumanbody,attackTcells,humanbody,attackcells,
damagethebodythirdspecificimmunedefenceandadiseaseto
thehumanimmunesystemcausedbyparalysis.Adiseasecaused
byparalysis.
Corebreakthrough
Instantapplication
3.2009December1stistheWorldAIDSDay.Isthetwenty-second
WorldAIDSDayisthefirstdayofthedisease,AIDSDay
propagandatheme"commondisease,theAIDSDaypropaganda
theme“andhumanrights”,advocatepeoplecareandhuman
rights”.AdvocatesthatpeoplecareaboutandsupportHIV
infectedpersonsandpatients,infectedwithvirusandpatients,
andfurthermobilizethewholesocietytoparticipateinAIDS
preventionandcontrolwork.ParticipationinAIDSprevention
andcontrol.ThefollowingstatementaboutAIDSisincorrect
Corebreakthrough
A.HIVcausesAIDS.AIDScausedbyparasitesinthelymphof
theparasiticonBlymphocyteparasiticintracellular
intracellular,destroythebody,simmunesystemtodine
togetherB.andAIDSpatientswillnotinfectAIDSC.AI.The
probabilityoftheoccurrenceofmalignanttumorsinpatients
withAIDSthannormalpeople.HighD.AIDSmainlythroughsexual
contact,thebloodandmother.AIDSmainlythroughsexual
contact,babyspreadinthreeways
Corebreakthrough
Analysis:parasiticinTlymphfineresolution:selectA.HIV
parasiticinlymphnodes.Parasiticinthecell,damagethe
body'simmunesystem,intracellular,anddestroythebody's
immunesystem,asaresultofthelossofimmunefunction,
immunefunction,AIDSpatientswithmalignanttumorshigher
thannormal.Theprobabilityofatumorishigherthanthatof
anormalperson.
Experimentalmonographicinquiry
Anoverviewoftheexperimentalcontrolprinciples
Theprincipleofcomparisonisoneofthestandardsfor
designingandimplementingexperiments.Bysettingthe
experimentforcomparison,oneofthemis.Bysettingup
experiments,wecanexcludetheinfluenceofirrelevant
variables,excludetheinfluenceofirrelevantvariables,and
increasethereliabilityandpersuasivenessofthe
experimentalresults.Thereliabilityandpersuasivenessof
theresults.
Experimentalmonographicinquiry
Usually,anexperimentisdividedintoexperimentalandcontrol
groups.Usually,anexperimentisdividedintoexperimentaland
controlgroups.Theexperimentalgroupreceivedtreatment
groupobjectexperimentalvariables;experimentalgroup
receivedgroupobjectexperimentalvariablestreatment;
controlgrouporcontrolgroup,theexperimentalgroupor
controlgrouphypothesis,andontheexperimentalhypothesis,
isnottoacceptthegroupobjectexperimentalvariable
processing.Objectgroupsprocessedbyexperimentalvariables.
Asforwhichexperiment,whichisthecontrolgroup,the
decisionisusuallyrandom.Whichgroup,asacontrolgroup,
isgenerallyrandomized.So,intheory,so,theoretically,due
totheimpactofindependentvariablesoftheexperimental
groupandcontrolgroupareequalandbalanced,effectsof
independentvariablesareequalandbalanced,sothedifference
betweentheexperimentalgroupandthecontrolgrouptwo,the
differenceinexperimentalgroupandcontrolgrouptwo,canbe
identifiedasfromtheeffectoftheexperimentalvariables.
Theeffectcomesfromexperimentalvariables.Accordingtothe
contentandformofthecontrast,thereareusuallyblank,self
control,anddifferent,usuallyblankcontrol,selfcontrol,
comparisonoftheconditions,mutualcontrol,fourkindsof
control.Fourcontroltypeswerecompared.
Experimentalmonographicinquiry
Actualcombatdrill
Accordingtotheimmunologyknowledgetoanswerthefollowing
questions:accordingtotheimmunologyknowledgetoanswerthe
followingquestions:(1)thefollowingisbasedonthenatural
immuneoftheoriginalscientistsherearescientistsbasedon
naturalimmuneresearch,researchofartificialimmune,
artificialimmune,immunefunctiontest:duringtheinspection
process:
Experimentalmonographicinquiry
Theexperimentassumesthat...Theinjectionheatingkilled
pneumococcidiedandlosetheirtoxicity,deathandlossof
toxicity,butitsantigencancauseimmunereactioninmice,
antibodyinducedinmiceimmuneresponsebytheantibody
inducedinmicebycellsynthesis.Cel1synthesizing.
Experimentalmonographicinquiry
(2)inthepreventionwork,fromtetanuspatientsinthe
epidemicpreventionwork,gettheserum,inthepreventionwork
inserum,toaninjectionoftetanustoxoidinjectioninthe
depthofinjectionindepthtrauma,trauma,butalsotreatment
oremergencyprevention,pleasedesignexperimentstoprove.
Prevention,pleasedesignexperimentstoproveit.
Experimentalmaterials:agroupofabout60weightaboutthe
experimentalmaterials:anumberofbodyweightofGmice,the
sizeandhealthstatusaresimilartothatofmousesmall
sterilesyringesandhealthstatusaresimilartothatofother
equipment.Otherequipment.
Experimentalmonographicinquiry
Experimentalprinciple:.Experimentalprinciple:.Experiment
procedure:experimentprocedure:firststep:.Firststep:.The
secondstep:secondsteps:..Expectedresults:expected
results:.
Experimentalmonographicinquiry
Answer:theanswer:(1)microbialpathogensinvivohas
inactivatedantigenscancauseimmuneresponse(other
reasonableantigencancauseimmuneresponseorother
reasonableanswers)canalsoanswerthepulp(2)
intraperitonealinjectionofexogenousantibodycanmakethe
machinebodyimmunityability(serumortetanuspatientsafter
injectionoftetanuspatients,serumimmunityortetanus
patientsaftertheantibodyinserumcankilltheinvading
tetanus)inthetetanusantibodycaneliminateinvading
Experimentalmonographicinquiry
Thefirststep:thefirststep:secondstepextractionfrom
serumtetanuspatients:selectonlyafewsimilarmice,second
steps:selectionofseveralsimilarmiceweredividedintotwo
groupsofequalnumber:theexperimentalgroupinjectedwith
immuneserum,equalinthetwogroups:theexperimentalgroup
injectedwithimmuneserumafterinjectionoftetanustoxoid
(orinjectionofimmuneserumandtetanusinjectionoftetanus
toxoidorinjectionofimmuneserumandtetanustoxoid,control
group),thecontrolgrouponlyinjectedtetanustoxoidmice
died,controlmicedied,thenormallifeofthemiceinthe
experimentalgroup
Caseanalysisofhighfrequencytestcenter
Testsite,thephysiologicalroleofimmunecells,example1
(2009collegeentranceexamination,Sichuanroll,pathogens,
differentimmunityyears,collegeentranceexamination,
Sichuanvolume)pathogens,differentimmunityyears,college
entranceexamination,Sichuanrollstatus,theprocessof
infectioninmiceasshown.Theprocessofinfectioninthe
statemiceisshown.Whatfollowsiscorrect
Caseanalysisofhighfrequencytestcenter
NonspecificimmuneA.celldeficientmice.Thephagocytosisof
damaged,damaged,cannotproducespecificimmuneB.Bcell
deficientmicecannotsynthesizeantibody,celldeficientmice
cannotsynthesizeantibodies.APCdeficientmicecannot
synthesizeantibodybutstillcanproduceimmuneresponsesin
C.Tcelldeficientmiceinvivointracellularpathogensthe
roleofantigen-presentingcells.Theantigendeficientmice
invivocannotbecompleted,withnotcomplete,humoral
immunitycannotproducecytokines,immuneD.miceandnormal
mice.Immuneproducedbylymph,strongspecificeffectsonT
cellsandmacrophagestotargetcells.Thespecifickilling
effectofeffectorcellsandphagocyticcellstotargetcells
Caseanalysisofhighfrequencytestcenter
[analysis]becauseofthesmallnumberofantigensinvadingthe
bodycannotthroughanalysis]phagocyticcellsandTcells
showeddirectstimulationtophagocyticcellsandcellsafter
presentingdirectstimulationofBcells,cellsofhumoral
immunity,makethebodytoproducespecifichumoralimmune
cells,makingthebodyproducespecific,byphagocytesandT
celldeficientmicestillretainafewphagocyticcellsandcell
specificimmunedeficientmicestillretainafewoptions,
options,errorerror;specificimmunity,A,theCoptionis
wrong;antibodyisbyBcellsafterstimulationwithanti
originaldifferentiationintoplasmacellsthatproducecell
antigenstimulateddifferentiationtheplasmacellsproduce
celldeficientmicecannotsynthesizeantibodies,andtheB
celldeficientmicecannotsynthesizeantibodies,butnotanti
synthesiscelldeficientmiceThebodybyimmunecellsimmune
tointracellularbacteriaasthecorrectoption;withthe
correctBoptions;lymphokineistoenhancetheroleof
effectiveoptionsrightcellstotargetcellsshouldbelethal,
thelethalityofTcellsontargetcells,phagocytosisofcells
withoutcellkillingforceontargetcells,thewrongoption
optionerror.Worked,theDoptionwaswrong,[answer]B
Caseanalysisofhighfrequencytestcenter
ArethereanyspecificimmuneresponsesinmicewithTdeficient
cellsthatarespecificforcelldefects?Immune?[hint]only
partialhumoralimmunity
Case
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