XXXX譚宏宇-藥品質(zhì)量風(fēng)險(xiǎn)管理

藥品質(zhì)量風(fēng)險(xiǎn)管理黑龍江省食品藥品監(jiān)督管理局藥品安全監(jiān)管處

譚宏宇第一章2010版GMP概述第三章質(zhì)量風(fēng)險(xiǎn)管理第二章藥品生產(chǎn)企業(yè)實(shí)施新版GMP存在的普遍問(wèn)題第四章對(duì)實(shí)施新版GMP的幾點(diǎn)小建議第一章2010版GMP概述

第一節(jié)新修訂藥品GMP的主要特點(diǎn)一、強(qiáng)化質(zhì)量管理體系建設(shè)，實(shí)施全面質(zhì)量管理，強(qiáng)調(diào)體系轉(zhuǎn)換關(guān)于實(shí)施《藥品生產(chǎn)質(zhì)量管理規(guī)范（2010年修訂）》有關(guān)事宜的公告（2011年第19號(hào)）二、藥品生產(chǎn)企業(yè)應(yīng)按照《藥品生產(chǎn)質(zhì)量管理規(guī)范（2010年修訂）》要求，建立和完善企業(yè)質(zhì)量管理體系，建立和更新符合本企業(yè)實(shí)際的各類管理軟件并驗(yàn)證和試運(yùn)行，組織開(kāi)展企業(yè)員工培訓(xùn)。相關(guān)工作應(yīng)在2013年12月31日前完成。二、加強(qiáng)質(zhì)量風(fēng)險(xiǎn)管理，明確提出了變更控制、偏差處理、糾正與預(yù)防和質(zhì)量回顧與分析等風(fēng)險(xiǎn)管理的要求三、強(qiáng)調(diào)了藥品生產(chǎn)與藥品注冊(cè)及上市后監(jiān)管的聯(lián)系四、增強(qiáng)了指導(dǎo)性、可操作性，方便開(kāi)展檢查工作第雪二房誠(chéng)節(jié)G僵M沃P的股原體則醒始軟終撲如能一一槐、籠藥精品浴的凍屬黎性（雜一智）俘藥具品虜是郵特限殊背商酷品（逼二酒）湊安脂全打、烤有俱效甚、肆均臂一躺穩(wěn)冰定攤、裳廉蛛價(jià)二輔、G敢M堪P的連原如則防薄止問(wèn)污燙染旦、柴交宏叉母污奮染擾、主混醬淆搏和則差乖錯(cuò)，剛保隔證吉產(chǎn)羨品球的肌質(zhì)控量兼均紐奉一覺(jué)和冊(cè)穩(wěn)萬(wàn)定帥。三奴、G塵M大P的節(jié)根畜本峰目餅的有貓效鑒防渴控址風(fēng)善險(xiǎn)第哈三厭節(jié)2校0暈1宰0版G俗M巷P的珍全萬(wàn)新此理兔念（界一塊）逐建巾立爬全架面徹質(zhì)枕量倍管柿理禮的脆質(zhì)欣量刃管備理溉體圖系全阿員烤參番與策組?？椫袊?yán)績(jī)密等職稿責(zé)遵清想晰皂流濟(jì)程鈔順鹽暢管寧控言到原位規(guī)措神施錢合疲理謎質(zhì)縮慧量證提慰升獅風(fēng)割險(xiǎn)狂降松低建彈設(shè)螞質(zhì)乏量點(diǎn)管少理泛體央系河是像從衫研灘發(fā)漫至度臨陶床早用勵(lì)藥委指茂導(dǎo)惑的贊藥銷品戀整行個(gè)并生災(zāi)命餓周渣期愧均造能前有醫(yī)效槽防最控帽風(fēng)恥險(xiǎn)承，虎持伶續(xù)全提灘高爸產(chǎn)腥品慣質(zhì)及量桿，現(xiàn)持相續(xù)百降摟低包成廢本沾的插必節(jié)要家保揚(yáng)證青。想包莊括閘：蕩研曠發(fā)暑生嶺產(chǎn)闖銷櫻售蟲(chóng)臨銀床匆指償導(dǎo)（橫二壺）愁突扁出雀質(zhì)鎮(zhèn)量筐風(fēng)伏險(xiǎn)界管食理宿在各質(zhì)府量拼管篩理低體謠系柏中子的鍛作悼用1素.質(zhì)厘量扣風(fēng)廁險(xiǎn)復(fù)管屠理倘理紫念痛滲越透圈在尤質(zhì)辱量工管摩理廚體翻系考的蹦各脫個(gè)跡環(huán)酸節(jié)質(zhì)妙量惹風(fēng)選險(xiǎn)砌管懼理=質(zhì)阿量露管嗚理2臘.質(zhì)磁量卷風(fēng)觀險(xiǎn)怎管槐理妖：彎在嫂整鐵個(gè)揮產(chǎn)屠品跑生蝴命妙周炸期贊中贏就填藥看品疊的毯質(zhì)如量評(píng)風(fēng)暢險(xiǎn)判進(jìn)顏行詞預(yù)物測(cè)拐、筆評(píng)建估緞、咸控休制申、隙溝武通避和日審責(zé)核靈的解系時(shí)統(tǒng)凈過(guò)舟程?hào)|。忍與巡壽質(zhì)訴量日體暢系視相乏結(jié)診合槍，假以訊科謙學(xué)戒數(shù)數(shù)據(jù)億、嗎知洪識(shí)蹦和區(qū)實(shí)障踐事經(jīng)喂驗(yàn)芽為堵指請(qǐng)導(dǎo)口，懲用冰以乘維蔑護(hù)踩產(chǎn)意品論質(zhì)扶量宴的瓜決石策泛過(guò)伶程下。3晉.質(zhì)脹量幫管盡理決體葛系聚是高以霸質(zhì)落量添責(zé)確任段體饅系禿為洋基恒本裕構(gòu)白架我，番防?？乇L(fēng)暫險(xiǎn)菊為脫行戴為禁準(zhǔn)寨則滋，希各裂子談系機(jī)統(tǒng)聞緊惰密駛配蒙合盆的熊有特機(jī)拴整鑄體愧。第岸三戶節(jié)2禍0蠻1太0版G遇M末P的抹全閑新瓣理生念（長(zhǎng)三豎）肯較9鍛8版G先M點(diǎn)P得還以窩突支出頃和議完臉善債的免內(nèi)誓容摩：1陰.重找視餐變職更司控賀制血、甘偏室差熔處握理賊、漲糾撤正歇與伯預(yù)紗防鄰、隸質(zhì)呈量柱回徐顧雀與每分帖析獨(dú)等減風(fēng)魯險(xiǎn)靜管況理辨核康心礦子胃系彼統(tǒng)蒸的酷建眨設(shè)捆與士管俱理2倦.弄餐虛齊作忘假交被誼視刻為以完山全竿不裁可逢接緊受驅(qū)的陶風(fēng)營(yíng)險(xiǎn)3里.注事冊(cè)債批說(shuō)準(zhǔn)僑的然工熄藝算和忌處濁方思的字法涼規(guī)嫁嚴(yán)壇肅淋性4堡.上戒市勉后啞的保質(zhì)椅量急追俗蹤5胃.委棵托鍛生貿(mào)產(chǎn)閉和辰委涼托歲檢蜓驗(yàn)第寒二穗章水藥糧品令生孟產(chǎn)衛(wèi)企井業(yè)涼實(shí)幼施侵新抽版G險(xiǎn)M棕P存吐在孝的頁(yè)普辜遍嫌問(wèn)華題一銷、珍將踢新嫩版G椒M高P簡(jiǎn)飽單田理紛解哲成灣為團(tuán)硬柜件紛改孟造桂和咱軟拳件邪增盾補(bǔ)姿。雨表練現(xiàn)刺在資：（腸一容）擠盲料目頁(yè)投略資吃改懇造梯硬洲件戒；（距二宋）尾風(fēng)評(píng)險(xiǎn)座管什理蠟工照具溉亂腸用棄；（漸三第）戚對(duì)雨標(biāo)安思陷想正嚴(yán)垮重爸，盲沒(méi)縣有鹽結(jié)岔合病企允業(yè)融自夏身脆的暫品鈴種撕特鹽點(diǎn)墳、澡管堤理叨模衡式常、矮人凡員合結(jié)輪構(gòu)隙和策現(xiàn)衣有件的畢生僚產(chǎn)斥條旗件指，雜硬壞性竭對(duì)著標(biāo)琴。穴導(dǎo)裕致罩只編見(jiàn)著樹(shù)很木傳不妄見(jiàn)冷森壯林儉，第使G訂M榨P形任式聞化恭、盲表箭面英化悼；第驗(yàn)二客章犯藥廚品成生早產(chǎn)穗企湊業(yè)貌實(shí)著施唉新假版G役M最P存括在禿的蹄普曬遍街問(wèn)頭題出礙現(xiàn)屢這烈些屯亂役象枝的校根強(qiáng)本讀原翠因劃：把掠通階過(guò)G嘗M晨P認(rèn)販證退作查為抵最泡終畫目稱標(biāo)勿，怠而跪非暗自財(cái)覺(jué)律實(shí)褲施G策M(jìn)舒P管插理商。惰半性攤較紅強(qiáng)毫，賤缺駐乏斯事俱業(yè)慮心罰和監(jiān)責(zé)嗎任揀心春。第田二喪章租藥使品漸生設(shè)產(chǎn)冠企期業(yè)卷實(shí)藥施陳新遷版G持M頑P存暫在諒的領(lǐng)普銷遍烈問(wèn)浴題二碼、稼片絨面兄認(rèn)脅為項(xiàng)實(shí)憶施G蒙M筐P就柏是松增堤加翻企剝業(yè)薪成坐本售，相沒(méi)西有爐從村企弱業(yè)扛綜胳合搭管感理時(shí)成黨本意和魔長(zhǎng)堪遠(yuǎn)啄發(fā)漿展?fàn)€角剃度跑認(rèn)陽(yáng)識(shí)G丙M響P。（耕一固）拴新暗版G乳M宣P提活高近了木企鳴業(yè)兩產(chǎn)鍋品彎的紗質(zhì)磚量廉保礎(chǔ)證遺能裁力枝，江降伶低言了遺發(fā)去生忽藥防害沾事哥件宇和元不捏合轉(zhuǎn)格才的扇風(fēng)煤險(xiǎn)惱。（后二狹）山新注版G稿M此P引桶入盾了已全種面拴質(zhì)滑量涉管枝理擠和向風(fēng)露險(xiǎn)度管拼理副的銹理規(guī)念瓦，惠企予業(yè)做可洋以猜利氧用賄加星強(qiáng)虛全抵面坡質(zhì)雪量尖管即理舌的姓機(jī)紐奉會(huì)稀，很完京善飄管崗理遮機(jī)捐制鼠，飄大粱幅材提頃高亭內(nèi)挺部徑的拿工忽作刪效淹率修，揀從毅而觸降瀉低叉管粗理餅成撥本皺。第權(quán)二誰(shuí)章鞭藥督品幅生垃產(chǎn)齡企佳業(yè)撓實(shí)宋施雄新耽版G合M崖P存驚在紋的脈普字遍邊問(wèn)晝題（切三削）分粗?jǐn)嚝E絨式鍋的矩管喚理島模蓮式遣不共能勿適夏應(yīng)粱未靜來(lái)五市馳場(chǎng)畏競(jìng)固爭(zhēng)脈對(duì)壁成烘本尿的哀要駐求臣，加而辜新功版G毀M晨P恰畫恰顆注早重絹細(xì)潔節(jié)允管祥理茄，混在眼實(shí)糟施G即M來(lái)P的謹(jǐn)同曲時(shí)孝，好可咸以輪利皺用G副M任P的冠理萄念嗽和布構(gòu)潑架協(xié)實(shí)目施兄精瓦準(zhǔn)逼的錢成貴本億控兼制宜，睡在室滿暑足芹質(zhì)案量毀要貸求敘的嫌前招提癥下讓，底節(jié)泉約振人騰工仔、我物券料捐、送能殲源肚等誤項(xiàng)譜的順開(kāi)竊支戀，小持臥續(xù)弱合勒理貿(mào)的樂(lè)降插低訊生貿(mào)產(chǎn)嚇成駛本壟。第練二采章攝藥寸品將生振產(chǎn)鄭企險(xiǎn)業(yè)既實(shí)院施憐新慚版G雨M煙P存較在利的烏普潔遍催問(wèn)酒題三島、汽資伸金欣不盲足炭，竄人保才運(yùn)匱滾乏脊。第料二項(xiàng)章隔藥賢品卡生恰產(chǎn)穗企搶業(yè)吸實(shí)嫂施雅新階版G割M股P存統(tǒng)在森的覺(jué)普浸遍摟問(wèn)駕題四潤(rùn)、饑正遣確緞理槐解蛛新敗版G偷M懂P（衫一團(tuán)）鴨新打版G墊M戰(zhàn)P的修工近作悲重齒點(diǎn)覆：建躲立壓質(zhì)漫量映管之理慌體促系臘是蠢實(shí)冠施送新惜版G餐M奪P的攏基組礎(chǔ)霸；質(zhì)脖量歲風(fēng)烏險(xiǎn)料管餅理迷是倒實(shí)咱施耀新偵版G烘M數(shù)P的黨根魯本另；轉(zhuǎn)駝變兵觀慢念趁是廢做礎(chǔ)好郵新放版G喪M泉P的麗前羨提拔。（葉二唯）解物決印好禍效仇益栽、石質(zhì)做量較和百風(fēng)縱險(xiǎn)燈的優(yōu)關(guān)細(xì)系E己R擋P、兆績(jī)捏效寸考著核唐與G悲M鋪P管至理傘的籠融步合舉，革使溉企彈業(yè)沈在堡持點(diǎn)續(xù)報(bào)控捆制屋和手降滋低啞成預(yù)本嶺的卵同父時(shí)削，霞能據(jù)夠獻(xiàn)有擋效股控柔制舟和梅降模低困質(zhì)虛量講風(fēng)晌險(xiǎn)盼。竟達(dá)沸到放高霞經(jīng)透濟(jì)度效怕益壞與沃低禮質(zhì)坑量兵風(fēng)僅險(xiǎn)誓的嘴雙落豐壘收慮。必倍須照解疑決琴好刺經(jīng)輸濟(jì)綠效測(cè)益襯和篇質(zhì)飛量畝風(fēng)備險(xiǎn)牙控磨制茫的垃矛哭盾勵(lì)。皆各述執(zhí)旨己朋見(jiàn)舒無(wú)什意挎于毯解衰決勝問(wèn)會(huì)題衣，者只錦有央尋怕找孟到鐮可起接桃受蕉的祖方洞案眾才睡能究解戲決刷矛錫盾閣。第顏三角章禁質(zhì)健量白風(fēng)叉險(xiǎn)峽管掙理第倦一撿節(jié)縫企析業(yè)底風(fēng)逃險(xiǎn)第塌二賺節(jié)紛建疫立踏全勁員踢參跌與隨的育質(zhì)但量均風(fēng)裕險(xiǎn)富責(zé)任抬體煤系第癥三必節(jié)化質(zhì)碌量真風(fēng)外險(xiǎn)能管阻理火規(guī)跌程銳。第普四府節(jié)蝦質(zhì)捷量駕風(fēng)工險(xiǎn)驚管丑理淚的吊自怎查慰自冠糾第案五扒節(jié)遷文謠件嫌的撿起絲式草斧、毫審嗓核頭和巾批膨準(zhǔn)第唱三猴章俯質(zhì)饞量譽(yù)風(fēng)兔險(xiǎn)柜管博理第冒一芝節(jié)熊企庸業(yè)郵風(fēng)蕉險(xiǎn)一洪、麻監(jiān)哥管佳法中規(guī)促風(fēng)友險(xiǎn)貪；大消匪防特法批、羽勞晌動(dòng)頃法殼等柏。二脆、蔑生旺產(chǎn)里安念全瘋風(fēng)采險(xiǎn)雹；叢人壇身羅、周財(cái)伍產(chǎn)品安掩全慘。三襯、心經(jīng)掘營(yíng)晴風(fēng)漠險(xiǎn)朵；廈經(jīng)晃營(yíng)檔戰(zhàn)禾略革決未策躍、隸市蕩場(chǎng)稿規(guī)之律慶與京預(yù)簽期饅、壞價(jià)允格滋策摔略協(xié)等椒。四揭、脹信衣譽(yù)動(dòng)（指品腳牌仇）塵風(fēng)梅險(xiǎn)膛；抄媒肝體秘、稀消取費(fèi)畜者奴等績(jī)。五近、述社需會(huì)瘦道燭德臭風(fēng)鍋險(xiǎn)些；桿居檢心擠叵爭(zhēng)測(cè)吵者侍的陶?qǐng)?bào)看復(fù)敏等姨。六徑、傍生獅產(chǎn)帽質(zhì)古量較風(fēng)回險(xiǎn)磁；軍危轟害回患耐者閣健罩康旬及粥生馳命篇。生即產(chǎn)要質(zhì)兩量傭風(fēng)窮險(xiǎn)殖是灑引北發(fā)嘉其插他耕風(fēng)菊險(xiǎn)宿的碼最絹直朵接塊因孕素進(jìn)！第添三翁章撒質(zhì)胞量銀風(fēng)禿險(xiǎn)漢管蛋理第罵二很節(jié)陳建名立鳳全玻員謎參孫與笨的灰質(zhì)枯量贊風(fēng)萬(wàn)險(xiǎn)裹責(zé)前任泰體梢系一傍、斬新耕版G享M捕P引鳳入邀的屆是榜全淚面肢質(zhì)減量討管勿理諒的炊概愿念岸和他模暖式革，祖全油員跌參票與犁是銅必鉗然落的乎要慕求問(wèn)。二牲、約質(zhì)煤量秘責(zé)車任底就建是佛承舉擔(dān)螞質(zhì)日量閣風(fēng)漠險(xiǎn)象。倦質(zhì)稅量盟責(zé)啞任陜不脂僅蠻僅錘是匙質(zhì)奧量柔受愛(ài)權(quán)蘿人唐、佳質(zhì)專量飲保是證汪部奧門宇的蹄責(zé)蹈任芹。拒每惑個(gè)館員土工復(fù)都蠢必糕須潑為香自塌己停造畏成蠅的賴風(fēng)撒險(xiǎn)亡和嚷面鈴對(duì)皇風(fēng)葉險(xiǎn)丑所單采睜取葡的解措跡施馳與絕決來(lái)斷申承宮擔(dān)益相魯應(yīng)燒的位責(zé)癥任煎。三遠(yuǎn)、乒企腎業(yè)溪實(shí)湊施最新網(wǎng)版G糠M循P必賣須肆結(jié)缺合塌行璃政仁、搭人盞事旨、蜜薪餃資歷等浴管砌理蹈工如作險(xiǎn)，敞詳緞細(xì)抵制魔定零各帥部典門稻、久各驕崗閘位晝和惜人泡員罰的都職助責(zé)怖和押?jiǎn)栄澵?zé)醋制蹄度落，朵將邀質(zhì)各量平責(zé)連任趕落松實(shí)呼到懲人沿。四茫、錯(cuò)質(zhì)苦量滲責(zé)像任握體揪系而是盾建勞立療質(zhì)確量歇管盤理饞體譜系蔥和只實(shí)出施芝質(zhì)騎量惱風(fēng)淘險(xiǎn)越管非理刊的趣基輕礎(chǔ)靜和系前懼提騰。第工三池章擺質(zhì)資量熊風(fēng)國(guó)險(xiǎn)陸管澡理第蘿三收節(jié)《質(zhì)電量響風(fēng)媽險(xiǎn)利管懇理繁規(guī)鮮程》管活什討么掀？誰(shuí)毯來(lái)沫管查？怎趟么著管驢？第應(yīng)三雪節(jié)《質(zhì)填量造風(fēng)督險(xiǎn)伴管衣理融規(guī)河程》質(zhì)戒量嫩風(fēng)夢(mèng)險(xiǎn)柳管灰理陪規(guī)祝程嘩是辛圍撇繞覽質(zhì)銳量瘡方襪針糊，怒以股防帽范株風(fēng)藍(lán)險(xiǎn)宮為首目拆的威，燦指宏導(dǎo)敵開(kāi)鳥(niǎo)展騾質(zhì)輝量冤風(fēng)究險(xiǎn)絞的嬸識(shí)淚別殖、砍分恒類求、判評(píng)主估蹦、太質(zhì)艙量拉回至顧稈與咸分廚析奶、菌糾雁正附預(yù)除防穴措捧施射、兩溝多通裙和末效革果洲評(píng)鑰價(jià)里等齊工吵作蛋的伶綱交領(lǐng)乎性登文捎件改。主井要瞎內(nèi)浪容胞：1秩.質(zhì)芒量輛方麥針2致.組汪織蘭機(jī)家構(gòu)3結(jié).責(zé)悼任疾體盆系4沿.風(fēng)芹險(xiǎn)護(hù)級(jí)且別曲劃響分購(gòu)原流則5喚.風(fēng)狡險(xiǎn)蜻的雞層播級(jí)舍管鳳理娘原竟則6寬.質(zhì)正量霜風(fēng)音險(xiǎn)握管醫(yī)理日的填主館要游內(nèi)綠容第交三錘節(jié)《質(zhì)場(chǎng)量憂風(fēng)初險(xiǎn)隙管凳理鄭規(guī)流程》一光、奴質(zhì)舟量掘方鄰針堅(jiān)己持粉質(zhì)肯量月優(yōu)蓋先論，尼兼陣顧纖成填本灑原環(huán)則嘴。泛依幕法融組畫織斬生兔產(chǎn)褲合剝格展藥僵品態(tài)，喉保斷證貼向找社旋會(huì)雷和混客懼戶賴提丹供繁安廈全迷、綁有武效北、日均暮一箭、溫穩(wěn)竟定瓣的匙產(chǎn)惡品弦；堪持串續(xù)棗研暑究到、組改奇進(jìn)掉工口藝呀和籍裝眼備塑，柏科杯學(xué)記提蔥高挪生蜘產(chǎn)即效石率揮和落質(zhì)貝量現(xiàn)管剩理謀與略控臣制鉆水鋤平長(zhǎng)，慎合硬理薄降健低泄生暴產(chǎn)跡成倡本瓶。第資三棍節(jié)《質(zhì)涂量周風(fēng)味險(xiǎn)光管呼理建規(guī)植程》二闊、晶組湯織刃機(jī)駛構(gòu)質(zhì)下量叫風(fēng)懇險(xiǎn)漸管懷理葛的纏組食織正機(jī)徒構(gòu)早與偽層族級(jí)婦管廊理崗位1崗位2崗位3采購(gòu)供應(yīng)倉(cāng)儲(chǔ)物流總工或總經(jīng)理質(zhì)量受權(quán)人質(zhì)量保證部/質(zhì)量風(fēng)險(xiǎn)評(píng)估會(huì)議質(zhì)量管理領(lǐng)導(dǎo)小組質(zhì)量控制工程設(shè)備技術(shù)研發(fā)計(jì)量銷售生產(chǎn)制造/車間行政人事崗位1崗位2崗位3崗位1崗位2崗位3崗位1崗位2崗位3崗位1崗位2崗位3崗位1崗位2崗位3崗位1崗位2崗位3崗位1崗位2崗位3崗位1崗位2崗位3第洋三滔節(jié)《質(zhì)特量隙風(fēng)狼險(xiǎn)敗管有理明規(guī)戲程》三柔、雹質(zhì)雅量宮風(fēng)貪險(xiǎn)賢責(zé)肚任原請(qǐng)則旁：哥全資員在參思與惹質(zhì)嶺量慢風(fēng)晝險(xiǎn)遼管徐理拒，范層姿層撿落競(jìng)實(shí)經(jīng)質(zhì)束量報(bào)責(zé)畜任忠，著建臭立餅質(zhì)自量錢責(zé)廳任噴考辛評(píng)賴機(jī)適制鏟，壤實(shí)羅現(xiàn)氣效慰益杠與家責(zé)末任圓掛贏鉤取。（1）億總速經(jīng)繳理報(bào)或枝總芳工般：全蠅面虧領(lǐng)俘導(dǎo)誓本非企曉業(yè)駁開(kāi)號(hào)展辨質(zhì)替量極風(fēng)凱險(xiǎn)倉(cāng)管叢理泡工疑作厘，哲對(duì)渠產(chǎn)羽品疲質(zhì)丙量領(lǐng)負(fù)白總落責(zé)葵。（2）巖質(zhì)絕量智管弦理逼領(lǐng)漂導(dǎo)托小亦組科：由拌總饑經(jīng)憲理古或租總救工夠任內(nèi)組紐奉長(zhǎng)蹈，仔分凳管維各粱相陷關(guān)捐部描門毫的惜副培總練任膝副銀組返長(zhǎng)斥，慚各巴相騙關(guān)哨部節(jié)門珍的違負(fù)填責(zé)愁人骨為攔組男員督。在蘿總蝴經(jīng)會(huì)理唯或階總奔工少的疼領(lǐng)朽導(dǎo)漂下懂，廉制粉定惰本簡(jiǎn)企蹤蝶業(yè)寇的優(yōu)質(zhì)痰量政方臭針撞和竊風(fēng)尼險(xiǎn)墾管弓理較目漠標(biāo)違，狐監(jiān)爸督硬質(zhì)房誠(chéng)量租風(fēng)增險(xiǎn)遭責(zé)坐任洗的國(guó)落覺(jué)實(shí)辦，步組窮織潑各固相蔽關(guān)耽部終門水對(duì)田重扮大強(qiáng)質(zhì)殊量托事翁項(xiàng)清或房誠(chéng)高丑級(jí)偽別關(guān)（A級(jí)撿）半風(fēng)冷險(xiǎn)逝質(zhì)收量腰事倍件喇進(jìn)竟行齊三選級(jí)踢評(píng)怠估望和考決抗策灘。第攜三德節(jié)《質(zhì)典量景風(fēng)石險(xiǎn)永管巷理貪規(guī)察程》（3）盈質(zhì)軟量狗受樹(shù)權(quán)纖人況及盜質(zhì)昌量枯保液證賢部縣：受齡質(zhì)篇量雁管嘗理作領(lǐng)悄導(dǎo)魯小動(dòng)組出的仁委纏派媽，釘領(lǐng)窗導(dǎo)視質(zhì)況量賽保礙證撥部裳，資貫趕徹纖企睛業(yè)面質(zhì)迫量淺方再針帥，男制鹿定政質(zhì)更量殘風(fēng)桐險(xiǎn)椅管絞理揪規(guī)肌程偵；獲監(jiān)爸督首落且實(shí)雀質(zhì)辣量員管縱理喝領(lǐng)毛導(dǎo)猶小晃組獅做晉出吹的際重頸大模質(zhì)乞量錘決亂策梯（幣包槐括阿對(duì)A級(jí)楊風(fēng)貨險(xiǎn)學(xué)做蒼出專的昏決煌策沃）測(cè)和鎮(zhèn)召蝕集或有攪關(guān)鐵部械門浮人傻員布對(duì)A級(jí)圓決清策里的塞執(zhí)葡行顛效晌果砌開(kāi)決展率評(píng)涂?jī)r(jià)漿；休監(jiān)當(dāng)督它質(zhì)代量牧風(fēng)按險(xiǎn)謙管陸理憶的頸日陶常洪執(zhí)謊行冠情母況杰，另包撿括債對(duì)屬一濕級(jí)矩評(píng)系估宮結(jié)栽論弓和純采光取乘的舒措溫施異進(jìn)狡行余二安級(jí)筐評(píng)絲式估由，窯對(duì)織評(píng)屯定旁為A級(jí)椅的熔風(fēng)覆險(xiǎn)缺事睜件項(xiàng)，乎立讀即缸報(bào)去告話質(zhì)歐量逼管梢理泊領(lǐng)坦導(dǎo)支小曾組忠，袖對(duì)括評(píng)建定腿為B級(jí)分的盾風(fēng)委險(xiǎn)氣事管件找進(jìn)泉行汪決照策掏、僅監(jiān)袋督吩執(zhí)迎行鐵和爺開(kāi)弓展編效巡壽果祝評(píng)膽價(jià)被，惡對(duì)逢評(píng)延定溝為C級(jí)籠的癢風(fēng)歲險(xiǎn)絲式事框件全向池有鬧關(guān)捷部更門角提瞞出肉建跟議擔(dān)和忠要扔求稈，紋由惑一扎級(jí)汁評(píng)議估尋部驚門情自花行累做泛出情決滔策熔，鹿并授對(duì)截決筍策北進(jìn)革行運(yùn)備智案盒、物監(jiān)棍督蜓執(zhí)平行投情否況磨，幻玉開(kāi)耗展展效獄果苗評(píng)脖價(jià)據(jù)；秘組爹織暴相制關(guān)港部演門界和發(fā)人敲員莖開(kāi)枝展抗質(zhì)輕量膝回輔顧灶與倒分價(jià)析鬼工末作浸；揀定忍期考向活質(zhì)急量困管烘理銜領(lǐng)旦導(dǎo)忽小鐵組勺提躁交層質(zhì)贏量吉安央全依分零析員報(bào)我告肆。第蠻三橡節(jié)《質(zhì)求量渴風(fēng)剪險(xiǎn)標(biāo)管們理制規(guī)沖程》（4）吵各喉相凡關(guān)著部閘門按混照米本濫部晉門工職熔責(zé)耐對(duì)巧影選響惠或貓可修能刮影概響測(cè)藥丹品殖質(zhì)剃量直的磁各梢種緞因武素敲采榜取晌有恒效林措柱施鋼加啊以角控廣制五，宏預(yù)辟防側(cè)發(fā)孔生滋不汁可森接旋受瘋的醋質(zhì)冤量割風(fēng)援險(xiǎn)發(fā)；婚采賞取沿應(yīng)爺急坑措患施鑰糾新正霧已糊經(jīng)案發(fā)鄭生卷的厭風(fēng)鉗險(xiǎn)萬(wàn)至米可樹(shù)接貼受奮范撿圍航；能監(jiān)館督萄所杠屬軌崗踢位直及呢人近員且認(rèn)就真孟履都行請(qǐng)崗申位珍職方責(zé)忌，津正廟確毛執(zhí)河行廟管掛理輔和消操有作彎規(guī)揭程技；昌對(duì)線本惱部夸門扛出通現(xiàn)貴的糠影捐響洪或艷可獨(dú)能睜影樣響捉質(zhì)籃量勇的嫩異蜘常婆情泊況州開(kāi)銷展充詳配盡狂的述調(diào)秀查炸和罰一魯級(jí)傅風(fēng)唇險(xiǎn)憶評(píng)假估閘，愁并撓與神相淺關(guān)囑部示門象和千人糞員首進(jìn)雪行鋒溝概通斜；犯及宅時(shí)辱向?qū)Ｙ|(zhì)喉量旬保射證咐部祖報(bào)疏告喪質(zhì)護(hù)量磚風(fēng)代險(xiǎn)瞇事淡件酸及濤一槐級(jí)名評(píng)斥估絲式結(jié)放論親；確對(duì)壟低柄級(jí)遺別叔質(zhì)刊量趕風(fēng)炸險(xiǎn)忽事賠件周進(jìn)脊行嚴(yán)決撈策崗；眉配聯(lián)合逆質(zhì)痰量副保扔證族部暈或離其際他叫部錢門鳳對(duì)騾中菜等皺級(jí)磨別裂以術(shù)上更質(zhì)柿量籠風(fēng)艇險(xiǎn)久開(kāi)炭展庫(kù)調(diào)短查普和燙風(fēng)襲險(xiǎn)世評(píng)疤估尚工鬧作環(huán)；劑正泰確塊執(zhí)襲行藥質(zhì)勾量淋管筒理儉領(lǐng)返導(dǎo)柄小疤組株和戚質(zhì)旬量泳保粥證伐部柜做紫出渴的瞞質(zhì)庭量澤決肅策估及障預(yù)熊防滴與束糾珠正亂措浙施逢；訴自本覺(jué)敢接白受筆質(zhì)并量梨受濾權(quán)拉人渠及友質(zhì)蛋量芹保百證骨部究的護(hù)監(jiān)帖督叉與鉗管蟻理?yè)酢５谔等龑庸?jié)《質(zhì)挽量賄風(fēng)京險(xiǎn)與管惜理候規(guī)為程》（5）漸崗謙位認(rèn)始真器履精行研崗涉位序職瘋責(zé)慮，誤正緞確盟執(zhí)拋行攪管靜理桃和伙操擊作瘋規(guī)維程隊(duì)；嫂對(duì)朗本吐崗勸位武影敞響網(wǎng)或映可像能卵影魯響曾藥盞品稻質(zhì)悶量科的敢各飛種惕因押素退進(jìn)斜行刑識(shí)套別砌，挖并慰采竭取踏有跨效菠措怖施嗽加仰以全控綢制道，跨預(yù)嶼防勤發(fā)再生今不距可迎接支受爪的浙質(zhì)等量頌風(fēng)斥險(xiǎn)河；公采趁取擠應(yīng)獨(dú)急共措誤施孩糾監(jiān)正碎已釋經(jīng)赤發(fā)亮生門的蓮風(fēng)憐險(xiǎn)纏至沾可暑接疫受賓范置圍零；騰向講所律屬也部褲門匪及肅時(shí)晴報(bào)伍告紗本酬崗盼位兼出閱現(xiàn)蟻的浙影仇響孝或冶可這能棄影見(jiàn)響境質(zhì)炸量梢的夢(mèng)異敵常匠情足況叉，司并組配送合劉開(kāi)歇展每調(diào)千查司和雀風(fēng)繳險(xiǎn)齊評(píng)龍估袍工障作濤；憲正饅確提執(zhí)終行謊質(zhì)謀量際管斧理暈領(lǐng)配導(dǎo)搞小凍組贈(zèng)、拆質(zhì)豈量暴保沒(méi)證屋部邁及好所毒屬撕部削門提做扭出畜的饅質(zhì)彎量譯決半策運(yùn)及季預(yù)巾防路與竹糾維正窗措輛施牲；近自鎖覺(jué)丹接蠅受栗質(zhì)馬量辯受瓦權(quán)廚人姥、友質(zhì)遙量差保煉證略部攻及致所厘屬露部技門奶的番監(jiān)逼督叫與俘管斧理鉤。（6）術(shù)各捷部跨門存及思所曠屬手崗抹位蘭應(yīng)朵設(shè)唐立唐風(fēng)百險(xiǎn)器管嗚理眉員購(gòu)，道具像體舅負(fù)奸責(zé)漫質(zhì)帝量著風(fēng)預(yù)險(xiǎn)柄的嘆日裙常勸組繭織前、豪管姓理炎和感溝皮通肆工狼作掘。第別三張節(jié)《質(zhì)貓量旗風(fēng)戒險(xiǎn)蹤蝶管逮理輔規(guī)壩程》四懶、勇風(fēng)雖險(xiǎn)裝級(jí)就別格劃裝分上原倘則（租一載）麗風(fēng)娛險(xiǎn)爸分茄級(jí)抹管居理毛，若不車能臣分蓬類榆管么理藥伸品烈生靜產(chǎn)按的陵組阻織亞過(guò)劉程郵極崗其丸復(fù)藝雜尊，膛影前響茅藥建品跡質(zhì)嶄量循的擱因住素箏眾短多慕，孟情卷況捉錯(cuò)陽(yáng)綜執(zhí)復(fù)熱雜費(fèi)，爛管嚷理寄難栽度席高層。突為兔規(guī)療范窄、示有企序塌地括開(kāi)帥展撞風(fēng)抱險(xiǎn)脈管廚理竭工碑作狹，用必躁須欺區(qū)閃分灑風(fēng)嗚險(xiǎn)溜的姨輕糕重耳緩?qiáng)始蓖?，?fù)區(qū)渣別走對(duì)蝴待桶。鞏同贈(zèng)時(shí)抵，語(yǔ)機(jī)加械婦、燒刻瞞板冒的斬歸故類吹法據(jù)難林以資涵掉蓋井無(wú)譽(yù)處謎不雅在濟(jì)的趁風(fēng)證險(xiǎn)鉤因盒素描，熄極秋易店造播成呆風(fēng)庸險(xiǎn)圖的剩誤袍識(shí)靠和神遺膝漏澡，景不權(quán)利吃于巴質(zhì)溜量巷風(fēng)妖險(xiǎn)評(píng)管雅理貝工惹作星的貌有柏效合開(kāi)伙展味。掉所渣以儲(chǔ)，駛風(fēng)你險(xiǎn)休管給理送的穴最第佳矮方跨法被是描按邪照計(jì)危顆害踩程朗度魚(yú)制患定忽風(fēng)仁險(xiǎn)建的服分因級(jí)欄原債則映，武在冷此奸原燭則玩的床指嶄導(dǎo)吃下眉憑恒借薯知校識(shí)洞、喊經(jīng)湊驗(yàn)肅和衫可耳靠果的唐數(shù)建據(jù)千，俗對(duì)待事裁件旅進(jìn)良行最具鬧體介問(wèn)對(duì)題救具凳體六分暫析垮，接即芳風(fēng)昆險(xiǎn)爐級(jí)妹別疊評(píng)版估錄。第黑三它節(jié)《質(zhì)昂量予風(fēng)啦險(xiǎn)該管嬌理呢規(guī)雷程》（矩二飾）檔風(fēng)歡險(xiǎn)酸級(jí)晝別罪的寧劃樣分A級(jí)壩風(fēng)市險(xiǎn)-嚴(yán)塞重載風(fēng)肝險(xiǎn)指分與尖藥肅品渠管嶼理垂的敞法岡律連法躲規(guī)鐘和副標(biāo)什準(zhǔn)催有蒼偏阿離顯，晉或及與從藥跨品G帝M遺P要犧求每有袍嚴(yán)燃重演偏菠離那，抗必夠然求造逮成室企葵業(yè)剪巨笛大桌的度經(jīng)拿濟(jì)天和撞名劫譽(yù)登損混失進(jìn)的歉；塞或遲產(chǎn)戰(zhàn)品零可探能房誠(chéng)對(duì)繡使堪用列者暖造苗成撫高只危挑健蘋康康損腦害橡的湯。對(duì)此職類率風(fēng)隊(duì)險(xiǎn)浸為姥不瞎可壞接里受椒風(fēng)液險(xiǎn)頸。高中危紙健乘康旁損紫害-致宮畸網(wǎng)、技致產(chǎn)殘矮、澤致醫(yī)突別變雷等爸不里可舉逆椅損匆傷聽(tīng)；暈或隨危京及執(zhí)生溫命掛，睜導(dǎo)逆致芒急財(cái)救量，乖甚寒至跪死頸亡玩；歪或最不蘭可側(cè)預(yù)鑼知立的駐損隱傷爸。專藥盾品桶自體然遷屬醫(yī)性薪導(dǎo)永致打的肢不駝良宰反抄應(yīng)連除秘外游。第錯(cuò)三朝節(jié)《質(zhì)該量史風(fēng)曉險(xiǎn)姜管洋理睛規(guī)葉程》B級(jí)暗風(fēng)波險(xiǎn)-主蟻要約風(fēng)檔險(xiǎn)指投與括企展業(yè)拜質(zhì)扶量旗方架針堂、遙內(nèi)膀部譯規(guī)逢程昏和遠(yuǎn)標(biāo)繡準(zhǔn)效，省或器藥吩品G樹(shù)M閉P要嶺求奇有控較糊大望偏播離匯，飼可遣能乏造哪成然企秤業(yè)侮較陵大病的片經(jīng)飾濟(jì)放和該名靜譽(yù)途損彩失刃的失；呀或穿產(chǎn)篩品射可長(zhǎng)能膠對(duì)個(gè)使固用竟者毒造笑成打非媽高墾危啟健撤康弱損淹害防的換。非賓高滾危灘健棒康閃損雷害-可睜預(yù)棋知條的序一刻過(guò)銳性幟的允可決逆音傷雁害孝或鋒療析效衡降液低賣，蜂不限需來(lái)要北急兄救模。信藥鋼品針自貍?cè)蝗箤倏p性殺導(dǎo)池致踩的賣不宏良如反執(zhí)應(yīng)獨(dú)除御外是。第盞三序節(jié)《質(zhì)殖量沙風(fēng)元險(xiǎn)筆管牲理箭規(guī)夫程》C級(jí)宰風(fēng)怎險(xiǎn)-指醫(yī)與接企乘業(yè)材質(zhì)屆量棗方軍針氏、引內(nèi)錯(cuò)部界規(guī)搜程摩和炎標(biāo)建準(zhǔn)賄，盟或緒藥匠品G厭M嗎P要淹求租有涉輕貧微協(xié)偏訊離等，刪可役能格造鍬成勵(lì)企艷業(yè)鋒一狼定春程葉度劍經(jīng)敏濟(jì)稱損饑失奸的反；鴿或誕提姐示明質(zhì)鋒量敗趨纏勢(shì)葉向谷壞葵，蹦不蠟加煉以嗓控漏制棍可朝能某發(fā)忽展剝?yōu)锳、B級(jí)忌風(fēng)觀險(xiǎn)伸的庭；鄉(xiāng)豐不贏會(huì)騰造渠成窗使痕用爭(zhēng)者數(shù)健洗康巷損灑害冬的黑。D級(jí)肝安校全植。第請(qǐng)三補(bǔ)節(jié)《質(zhì)啊量蠢風(fēng)勇險(xiǎn)歲管壯理突規(guī)裹程》五伴、耳風(fēng)火險(xiǎn)滾的掃層策級(jí)意管料理戀原踐則（都一暈）額風(fēng)幫險(xiǎn)曬層監(jiān)級(jí)捎管季理糊的死原缸則炎：①濁根蝴據(jù)趕風(fēng)功險(xiǎn)堅(jiān)級(jí)屋別抄，舞分找層水級(jí)觀開(kāi)避展?fàn)N風(fēng)簽險(xiǎn)壓管那理難工碧作東。橫層援級(jí)男越皂高章，玩負(fù)譯責(zé)賣管握理習(xí)的鞋風(fēng)宏險(xiǎn)姑級(jí)墳別耽越毒高齊。A級(jí)葉風(fēng)作險(xiǎn)—質(zhì)攪量梨管你理竄領(lǐng)舞導(dǎo)欣小糧組B級(jí)挖風(fēng)趟險(xiǎn)—質(zhì)梅量溉保務(wù)證板部C級(jí)較風(fēng)泡險(xiǎn)—各括部春門②意風(fēng)袖險(xiǎn)餅管后理始實(shí)箏行妙閉藝環(huán)奏管算理論模稼式栗。（吧二吸）咸風(fēng)俘險(xiǎn)環(huán)管第理駝的謠程品序泥：風(fēng)晚險(xiǎn)便識(shí)缸別然、跟風(fēng)完險(xiǎn)叫評(píng)走估請(qǐng)、漏預(yù)筒防再與貪糾爐正像、術(shù)必拋要露的屋確悄認(rèn)僻與班驗(yàn)柴證決、深效股果初評(píng)潤(rùn)價(jià)鈴、忌文填件涌修冶訂吐。（線三腦）蚊風(fēng)濕險(xiǎn)圣管促理專的拋三邀個(gè)你階巧段?。寒a(chǎn)姿品腳上誕市襖前籍（G宮L黑P臟/政G付C拜P林)、柱上派市粉中(錘G灣M議P織)、退富市扒（G旬M束P）第躲三明節(jié)《質(zhì)薯量魂風(fēng)說(shuō)險(xiǎn)喇管抵理插規(guī)烈程》六麗、纖質(zhì)餅量蓬風(fēng)板險(xiǎn)描管泊理暈的煙主賭要?jiǎng)艃?nèi)有容（但一規(guī)）G盯M晉P的縫質(zhì)煮量防風(fēng)友險(xiǎn)謹(jǐn)管偷理縣系鼻統(tǒng)男構(gòu)擠成1杰.廣趕義秧的臣系旅統(tǒng)疫構(gòu)杜成2喜0遵1篇0版G達(dá)M境P第鎮(zhèn)二撤章尺至卸第鎮(zhèn)十墊三左章漆的筒內(nèi)甘容寬，奔共道計(jì)忙十認(rèn)二閱個(gè)燦子蓄系青統(tǒng)寒。2量.質(zhì)隙量步風(fēng)傳險(xiǎn)怪管晶理妨的虛核獎(jiǎng)心菌子后系哀統(tǒng)變糠更劣控不制晌、險(xiǎn)偏犯差滔調(diào)囑查閱與靠處凡理程、揚(yáng)質(zhì)肌量米回朝顧杯與狐分巷析帖、它糾構(gòu)正根與僻預(yù)勤防浮、酒確礦認(rèn)乞和糧驗(yàn)罵證第租三柱節(jié)《質(zhì)泥量幟風(fēng)趟險(xiǎn)鼠管孫理凝規(guī)滔程》質(zhì)螞量而風(fēng)欲險(xiǎn)編管瘋理松文見(jiàn)件防系上統(tǒng)蓬關(guān)沙系隊(duì)圖變更控制子系統(tǒng)上市前的風(fēng)險(xiǎn)管理系統(tǒng)GLP/GCP上市中的風(fēng)險(xiǎn)管理系統(tǒng)GMP《質(zhì)量風(fēng)險(xiǎn)管理規(guī)程》退市后的風(fēng)險(xiǎn)管理系統(tǒng)GMP質(zhì)量管理體系偏差處理子系統(tǒng)質(zhì)量回顧與分析子系統(tǒng)糾正與預(yù)防措施子系統(tǒng)質(zhì)量管理機(jī)構(gòu)與人員廠房與設(shè)施設(shè)備物料與產(chǎn)品確認(rèn)與驗(yàn)證文件管理生產(chǎn)管理質(zhì)量控制與質(zhì)量保證委托生產(chǎn)與委托檢驗(yàn)產(chǎn)品發(fā)運(yùn)與召回自檢第寸三煙節(jié)《質(zhì)戒量鞭風(fēng)涌險(xiǎn)吩管黃理肢規(guī)決程》（屠二料）胳各副子郊系英統(tǒng)吵在絡(luò)風(fēng)溉險(xiǎn)罰管備理盯中亡的捕作岸用1部.變庭更忌控禁制雜系警統(tǒng)奏：是閘質(zhì)底量崗管瘡理帖體清系嶼中若預(yù)貓防腹變敏更潮對(duì)蜘產(chǎn)鴨品我質(zhì)篩量綱產(chǎn)置生扮不稱良促影丈響鬼（吊風(fēng)疑險(xiǎn)疏）約的膊系推統(tǒng)附。管紀(jì)理我內(nèi)撥容胳包提括槳：可輸能猶影衰響憤產(chǎn)晌品慶質(zhì)功量逝的唇所北有膽變部更馬。侮確陣定灣管糊理鼻程催序爬，綱明牢確葬各南部謎門秀的唐責(zé)歇任流。管浴理懶程患序猶包渠括朱：變筍更盯提寶出懼、凳風(fēng)勺險(xiǎn)新評(píng)鉗估押、搭決錫策乘與浴批何準(zhǔn)憲、左執(zhí)死行叛與恐監(jiān)魔督智、廉效吩果離評(píng)蓄價(jià)婚、蛋回仔顧兼與堂分臨析飯。變足更初的顏風(fēng)篩險(xiǎn)喚評(píng)燈估吊級(jí)臨別想：按冷風(fēng)送險(xiǎn)船的及嚴(yán)睜重稍程丘度茄由作重英到覺(jué)輕支分寇為A、B、C、D四叨個(gè)咸級(jí)砍別咬。管宅理獄原桌則雞：變嗎更匆風(fēng)跨險(xiǎn)寫分義級(jí)夜不花分協(xié)類嶄；脅全薯員頌參紹與率變襖更仿控猴制扭過(guò)姜程側(cè)，謊按憤風(fēng)溫險(xiǎn)汗級(jí)圖別融實(shí)該施混層伶級(jí)拘管樂(lè)理原；笨變墊更助全關(guān)過(guò)悠程困處菊于煤受蜘控序狀虹態(tài)掃。文消件顆制掙定泥與仗修闊訂困：由匠質(zhì)戶量飛管爭(zhēng)理厲部擾門大起碼草奪、唇修劍訂《變避更僑控觸制茶規(guī)席程》，詳征通求袖各御相列關(guān)暴部秒門準(zhǔn)意略見(jiàn)嘴，萬(wàn)經(jīng)犧企走業(yè)盆質(zhì)框量撲管養(yǎng)理息領(lǐng)時(shí)導(dǎo)霉小臟組碑討宅論廟通媽過(guò)添，峰由臣總滿經(jīng)續(xù)理液（晌或盆總玻工莫）納批躍準(zhǔn)石執(zhí)抹行堵。第禾三它節(jié)《質(zhì)申量刻風(fēng)池險(xiǎn)藝管戚理發(fā)規(guī)款程》2膚.偏尾差較調(diào)貍查柳處抹理葛系庸統(tǒng)創(chuàng)：是商質(zhì)測(cè)量場(chǎng)管男理導(dǎo)體斑系毅中晨對(duì)統(tǒng)已迷經(jīng)奔發(fā)抓生首的艦影飛響正藥慚品蹦質(zhì)艙量泄的西事桃件趟進(jìn)風(fēng)行幣風(fēng)寒險(xiǎn)星調(diào)布查監(jiān)和絲式處戲理菊的茶系六統(tǒng)絕。偏讀差左：廣充義鬼的亦理發(fā)解卷是瀉涉界及駝產(chǎn)巾品趨質(zhì)假量睛的咐非古正塌常蒜事組件舊均慨為刺偏廣差刻。就分慎為盛量霜化央偏集差濟(jì)和詠非打量偷化寺偏目差坐。臘量映化酒偏東差涂標(biāo)螞準(zhǔn)芒是測(cè)通漢過(guò)躲積斑累勁匯寸總截與排生宜產(chǎn)走和猛檢掛驗(yàn)飛有葵關(guān)陵的條所怕有定參坡數(shù)悄和塑數(shù)料據(jù)睜，寸制宿定辛和喂修比訂肺多葛級(jí)寸內(nèi)忙控蒸質(zhì)簽量酬標(biāo)鴿準(zhǔn)已；辣非理量號(hào)化謹(jǐn)偏肆差翠是編無(wú)辮法捷用幻玉數(shù)罰據(jù)年進(jìn)觀行步判悔斷其，街但蘆違簽背育了G富M敏P、夸內(nèi)其部愚規(guī)者程某、靜標(biāo)驕準(zhǔn)瓣等師異慨常暗情起況否。管蕉理久內(nèi)幸容槐包菜括頑：制頌定站偏鴨差催的種定桐義菊；確撇立律偏馬差峽標(biāo)局準(zhǔn)動(dòng)；確泡定統(tǒng)管柱理姑程逢序?qū)?，柱明寺確邁各棟部躁門們的釘責(zé)詠任尚；對(duì)然出戰(zhàn)現(xiàn)奪的這數(shù)燙據(jù)給偏制離仿、容違膛規(guī)完行奶為役，虧以畏及搖可閑能蒸影閘響擦質(zhì)訊量悲的僚各扭種阻異故?？智榧r拘進(jìn)絡(luò)行塌風(fēng)多險(xiǎn)州調(diào)漿查類和祝評(píng)蜜估怪，軍并勿根悲據(jù)邁評(píng)訊估耗結(jié)聚論投做協(xié)出罩處賤理鎮(zhèn)決積定冶；根烤據(jù)肯該色系峰統(tǒng)遙的罩監(jiān)憂測(cè)洗、虹評(píng)丟估恰情要況饞及租時(shí)壁提顆出錦相駛應(yīng)控的沈質(zhì)鉆量誼管驗(yàn)理誓改勉進(jìn)賞措臘施完，扛消拔除紀(jì)風(fēng)艘險(xiǎn)香因扶素佳或光降曾低妹偏誤差它出斯現(xiàn)火的舒頻填次境。管欺理病程窄序謹(jǐn)包棗括版：定伴義穩(wěn)本趁企扣業(yè)頁(yè)的貌偏乞差孔；潔制具定菠生緞產(chǎn)侍和疤質(zhì)機(jī)量珍管濟(jì)理庸的模偏池差酷標(biāo)悔準(zhǔn)喇，哪具良備弟數(shù)賽理挪統(tǒng)厘計(jì)晨條吩件陣的皂標(biāo)徐準(zhǔn)駁必炎須掩制管定旅警略戒流限疏、鵝糾鄉(xiāng)豐偏舌限晴（扯內(nèi)木控蓮限攀）賭、膠超稅標(biāo)翠限籮等喚限協(xié)度沙，饞既絮多穗級(jí)驕內(nèi)致控猾質(zhì)討量促標(biāo)哥準(zhǔn)淘；壞偏斜差宿的鉗確瓜認(rèn)運(yùn)與灑報(bào)石告隙；葛偏蘋差保的布調(diào)榜查碰與點(diǎn)風(fēng)源險(xiǎn)倒評(píng)貪估拐；梯提懸出飯糾廢偏蘭措暑施您；句決財(cái)策擦與摔批潤(rùn)準(zhǔn)違；輕執(zhí)筑行擺與呈監(jiān)陰督惱；罷糾怕偏攜效謊果虎評(píng)瞞價(jià)茂；聯(lián)質(zhì)左量萄回過(guò)顧鍛與鐘分對(duì)析岔；丹系敘統(tǒng)繭的易改食進(jìn)譯措卸施毒。第同三鑄節(jié)《質(zhì)虧量而風(fēng)棗險(xiǎn)州管優(yōu)理梳規(guī)牢程》偏尚差眠的摸風(fēng)慘險(xiǎn)踐評(píng)地估感級(jí)舍別紐奉：按擱偏諒差牌可災(zāi)能臘造味成郊的尤風(fēng)丑險(xiǎn)昌嚴(yán)少重樂(lè)程或度談?dòng)纱字厝鄣蕉栎p戚分伴為A、B、C、D四槽個(gè)垃級(jí)董別融。管抱理背原類則銅：定校義吊準(zhǔn)積確鞠，羽標(biāo)禁準(zhǔn)降適烤度晚；仇風(fēng)竟險(xiǎn)棗分踐級(jí)孝，翻層蜂級(jí)睜管餐理鐮；泄全串員戀參宣與在，養(yǎng)分風(fēng)工趨明久確夜；才糾持偏欠得竿當(dāng)思（既合智法牲、栽科扁學(xué)譜、嬸及鏡時(shí)筍、姐經(jīng)硬濟(jì)侄）檔，籌跟戰(zhàn)蹤恒問(wèn)噸效嘉；商過(guò)滅程凡受槽控圓，哈適磚時(shí)先回樂(lè)顧宜。文改件既制議定宋與呆修艦訂級(jí)：由懸質(zhì)座量嘗管擇理箱部淡門假起汁草波、嗎修勁訂《偏狡差束管直理珠規(guī)羨程》，怨征醒求出各聲相們關(guān)搏部唐門窄意銅見(jiàn)糊，剝經(jīng)完企蓋業(yè)僅質(zhì)何量謠管孕理需領(lǐng)靈導(dǎo)毅小掩組悄討的論向通黃過(guò)牙，扇由漁總猛經(jīng)毒理值（蠶或莫總趕工慣）津批揚(yáng)準(zhǔn)司執(zhí)趴行鏡。第券三嚷節(jié)《質(zhì)淡量敞風(fēng)鉆險(xiǎn)候管篇理下規(guī)雖程》3比.質(zhì)享量羞回夾顧饑與與分冒析臟系惕統(tǒng)：仙“騙定克期羊”柿對(duì)烏所蓋有鏟生看產(chǎn)紋的惕藥喬品丙按橡品血種診進(jìn)麻行磁產(chǎn)騙品者質(zhì)明量舅回尾顧瘡分借析寸，婦以屈確次認(rèn)謝工王藝今穩(wěn)季定蜘可妨靠敞，嫌以模及祝原承輔愈料升、取成吃品圾現(xiàn)及行哄質(zhì)療量掙標(biāo)允準(zhǔn)老的晚適彼用饅性弟，觀及除時(shí)唯發(fā)素現(xiàn)棟不緣瑞良坦趨濟(jì)勢(shì)羞，窮確野定棉生同產(chǎn)兼及佳質(zhì)周量傲管佩理駕工組作抽改繞進(jìn)竹方郊向錢的洪系磁統(tǒng)衡。吉是船以玩品袍種掛為資單寧位助，陰采虜用仔以埋點(diǎn)捆帶待面推的鼓方宜式劫全撥面膠總北結(jié)展生妙產(chǎn)莖和蔬質(zhì)俊量膝管剖理刻現(xiàn)現(xiàn)狀囑，賺確膀定事改宜進(jìn)愿方磨向仆與到措敘施語(yǔ)的過(guò)系農(nóng)統(tǒng)輕。管絕理揀內(nèi)吉容賣包鵝括非：確而定壯開(kāi)車展鞋質(zhì)旱量江回弄顧寧分未析黎的搏周買期廁，界可旗以將是埋時(shí)涂間獄節(jié)怎點(diǎn)狠，痕或巡壽是常批虛次荷節(jié)沖點(diǎn)命，紋或悼是目質(zhì)業(yè)量宏?duì)顣鐩r豪節(jié)益點(diǎn)犁；遷設(shè)勢(shì)定有應(yīng)境該來(lái)開(kāi)婆展脅質(zhì)骨量鈔回狀顧旁分蟻析翼的域品及種排條抱件憂，放比懂如坡批聽(tīng)次害數(shù)及量脾、紫各環(huán)種錦變葛更嘉情包況冠、完偏遺差誕頻直次所及恐糾迎偏霞情傲況均等扮；妙確洞定濱質(zhì)拖量術(shù)回古顧享分顏析瞞的濟(jì)內(nèi)桑容魚(yú)和謹(jǐn)方宰法鞏；仙確擠定珍管劍理啄程哲序劉，市明宅確農(nóng)各佛部繼門陳的淘責(zé)子任治。管躁理乳程公序吩包緒括茫：質(zhì)必量徹部奪門浙按票照嫩周獵期秘和藝設(shè)屈定續(xù)條耐件卵隨必時(shí)翠確觸定腥開(kāi)胸展版質(zhì)墳量蔥回曲顧往分桃析兄的級(jí)品影種物目定錄耽；饑根意據(jù)禁回帳顧免分督析鹽的話目尿的挎，攏確槳定商具巨體幕品漏種色的欠回或顧擴(kuò)分覽析蚊內(nèi)求容劃和徑方箱法簡(jiǎn)，費(fèi)準(zhǔn)撈備段歷蹈史凱資婦料拼和垃數(shù)賴據(jù)暈；無(wú)開(kāi)游展龍分抱析星；英做豪出滾結(jié)吊論油，到指斜出早現(xiàn)巨存嫁風(fēng)車險(xiǎn)啟及尼級(jí)保別案，鴿提睛出紗改戴進(jìn)夫建緞議帽和蕩措醋施玻，良并懸形蹲成臥報(bào)舌告找；希上跑報(bào)顫質(zhì)猶量局管醫(yī)理更領(lǐng)架導(dǎo)恰小猾組降，殃做葉出柜改福進(jìn)槍決猾定紅；跨制回定爛改仗進(jìn)阿計(jì)徐劃首；咱改聰進(jìn)患措對(duì)施競(jìng)的豬執(zhí)幅行跨與梯監(jiān)維督重；對(duì)改蒼進(jìn)凱效看果疲的慣確按認(rèn)異；陜完喪成側(cè)改倘進(jìn)剃報(bào)瞎告置。第萍三垂節(jié)《質(zhì)蘭量巷風(fēng)歌險(xiǎn)菠管莖理強(qiáng)規(guī)競(jìng)程》質(zhì)晶量冤分溫析聚與煎回閃顧邁的朽風(fēng)撿險(xiǎn)胃評(píng)奏估釀級(jí)槐別貍：按把偏返差歌可侮能祥造壞成冶的叨風(fēng)束險(xiǎn)院嚴(yán)輝重星程貪度敘由兄重軟到縱輕優(yōu)分撈為A、B、C、D四耀個(gè)桃級(jí)序別枕。管遣理塔原錫則論：定至義扎準(zhǔn)葛確落，葛目燦標(biāo)辣明亦確霜，慢周哈期勝合辨理念，偶條致件聚適喉度炸；息回旬顧缺內(nèi)吼容逢完礦整現(xiàn)，妙分繪析刪方利法殼科道學(xué)沖，虧結(jié)刻論梨準(zhǔn)憶確??；挑風(fēng)知險(xiǎn)忍分和級(jí)腿，猾層鬧級(jí)堆管偉理橋；州全欺員裝參繪與釀，舉分藝工潔明裁確因；挎改耍進(jìn)辨措依施塞得餡當(dāng)偷（遞合莖法凝、鞠科口學(xué)穿、性及詠時(shí)偽、坦經(jīng)喘濟(jì)笛）孤；李跟悄蹤傷問(wèn)偷效質(zhì)；便過(guò)姓程宴受摧控高。文去件眼制遞定枯與汪修票訂猶：由絕質(zhì)絕量鋒管昌理蹈部厭門謹(jǐn)起艷草巷、線修版訂《質(zhì)佩量含分靜析申與但回齒顧宰管拌理徑規(guī)灰程》，拋征適求夫各祥相陡關(guān)丟部減門遣意粗見(jiàn)替，課經(jīng)心企抗業(yè)妹質(zhì)歉量歌管室理俯領(lǐng)間導(dǎo)況小椅組育討紹論珠通食過(guò)主，少由必總思經(jīng)猶理?。☉c或撇總稻工模）英批天準(zhǔn)秩執(zhí)杰行功。第言三薪節(jié)《質(zhì)授量魔風(fēng)遇險(xiǎn)尾管伯理棉規(guī)瘋程》4刻.糾釣正郵與蜘預(yù)激防凡系忍統(tǒng)范：是狹基后于胳變概更鼠、蠅偏胡差反和神質(zhì)悠量只回嚇顧朵分壞析嶺系紹統(tǒng)偽的薯運(yùn)炒行斃，事對(duì)漲已津出華現(xiàn)灶的滴生巷產(chǎn)渣質(zhì)御量愿問(wèn)坊題惠采鏟取制補(bǔ)袍救宣和庸改命進(jìn)手措孔施勇，身對(duì)棚可役能芒出逃現(xiàn)際的通生成產(chǎn)志質(zhì)規(guī)量葉問(wèn)譯題劫采惕取肆預(yù)頌防覽措框施撞的趴風(fēng)俱險(xiǎn)扭控艦制儉系診統(tǒng)駛。管布理嚼內(nèi)津容阻包演括焰：針勁對(duì)炕變沫更甩、眉偏靈差諷和叫質(zhì)癥量刪回隔顧芳分半析眾系勸統(tǒng)恒對(duì)誘存趣在岸的肚生疼產(chǎn)別質(zhì)數(shù)量尚問(wèn)監(jiān)題穗的世調(diào)罩查四分倒析盞結(jié)饑論關(guān)和趕建滑議堅(jiān)采辯取燃的帝措聾施轟進(jìn)抗行阿評(píng)給估累和錢完觸善造，街以螞期齡將收風(fēng)氏險(xiǎn)謀降竿低認(rèn)到逃可六接順受耕范杠圍紙；魔監(jiān)王督瞇措情施從的洞執(zhí)茅行懲過(guò)柔程班；限評(píng)宵估嗽采詳取播的槍措部施翼是句否柳達(dá)雙到鉆預(yù)液期供的文標(biāo)駕準(zhǔn)北。管竿理汁程佳序涂包蝴括建：確愚認(rèn)賞變?yōu)└?、穴偏慮差揚(yáng)和衣質(zhì)逼量杠回鍬顧某分屢析昏的州調(diào)亞查撥過(guò)雪程窩、盆結(jié)硬論餡和勁建逐議謹(jǐn)；至評(píng)仆估環(huán)擬倚采持取艷措乖施林的燒合燭理表性階、志有狗效劍性困和趴充危分許性綁；采制鈴定頸執(zhí)撫行仙計(jì)額劃趨；毯監(jiān)倚督挺計(jì)早劃鉤的紡實(shí)緩施艘；怠評(píng)鵝估絡(luò)補(bǔ)肯救袖或壘改對(duì)進(jìn)防效率果零；魄形討成紙報(bào)述告?zhèn)?。第碰三肅節(jié)《質(zhì)武量井風(fēng)嫩險(xiǎn)案管這理洗規(guī)慕程》糾腔正叔與叮預(yù)難防制措默施繼的遞風(fēng)棵險(xiǎn)投評(píng)寬估老級(jí)叫別然：按聚擬扮采耗取克措璃施術(shù)可圈能貢造本成紐奉的尿風(fēng)至險(xiǎn)堡嚴(yán)蕉重絞程那度辮由敢重捎到犬輕叼分準(zhǔn)為A、B、C、D四恒個(gè)逗級(jí)毅別節(jié)。管撥理執(zhí)原刷則值：前熔期泰工級(jí)作示過(guò)佛程已規(guī)盯范侵，駐內(nèi)房誠(chéng)容養(yǎng)全坑面遺；遙分爺析貓方球法豆科伯學(xué)凝，尾結(jié)尸論當(dāng)準(zhǔn)蜓確餃；每擬錄采夕取趴的鏟措魯施生合獲理曬；橡風(fēng)投險(xiǎn)現(xiàn)分壤級(jí)威，授層北級(jí)傲管廉理瞇；煤全盲員敢參索與籍，赴分同工煉明臭確勉；超信蠅息刷傳炊遞既準(zhǔn)川確較無(wú)杠誤犬；悠保夏證持監(jiān)疲督觀到熔位蕉；房誠(chéng)結(jié)堆果攪符撿合譽(yù)標(biāo)咬準(zhǔn)吉；封過(guò)滾程母受俘控渣。文珠件撿制我定糖與兇修惜訂勇：由震質(zhì)合量隆管挪理左部牲門嗓起奴草鼓、嗽修聰訂《糾譜正仰與穴預(yù)嫌防鋪措過(guò)施關(guān)管牲理舟規(guī)疾程》，心征甚求鵝各員相誕關(guān)穗部崗門瓦意哲見(jiàn)拿，諷經(jīng)取企策業(yè)貫質(zhì)桿量摔管咱理悉領(lǐng)昂導(dǎo)萄小船組隊(duì)討巾論計(jì)通翁過(guò)萬(wàn)，館由號(hào)總焰經(jīng)河理湊（宰或艱總牢工桂）亂批垂準(zhǔn)胸執(zhí)嫌行形。第刊三信節(jié)《質(zhì)喪量屢風(fēng)暈險(xiǎn)蟲(chóng)管集理積規(guī)世程》5垃.確手認(rèn)療與套驗(yàn)點(diǎn)證允：是細(xì)保織證閣風(fēng)埋險(xiǎn)勿管縱理山各搶核跳心浮系陪統(tǒng)芽正潔確程運(yùn)狂行我的懶質(zhì)蓬量敏風(fēng)雪險(xiǎn)兵管籮理房誠(chéng)系點(diǎn)統(tǒng)役。徐是宮衡賽量嗽糾乏正耗與韻預(yù)捎防販措揭施威是濫否鋒達(dá)陳到室預(yù)屯期幻玉標(biāo)笨準(zhǔn)筐的肢重迅要繼技通術(shù)爹確運(yùn)認(rèn)連系蓋統(tǒng)招。第怕三薄節(jié)《質(zhì)膽量屑風(fēng)球險(xiǎn)法管懸理姐規(guī)其程》（標(biāo)三放）稠各山子幕系茶統(tǒng)到在飼風(fēng)律險(xiǎn)淹管導(dǎo)理史中箭的濁相倆互睜關(guān)倉(cāng)聯(lián)5個(gè)福核可心已子泉系彼統(tǒng)駱之旺間階應(yīng)艘進(jìn)省行荷有裝效秤的苗溝涉通未和刑銜笨接霜，卻既運(yùn)互晨為裙補(bǔ)便充寫，話又孔相俯互改轉(zhuǎn)纖化扶與膊制看約司，燒使汪質(zhì)棒量焰風(fēng)利險(xiǎn)謠管穩(wěn)理畫體叛系超成舅為眠一皆個(gè)拔統(tǒng)攪一納的膊有最機(jī)圖整境體削。質(zhì)量風(fēng)險(xiǎn)管理變更偏差回顧分析糾正預(yù)防確認(rèn)驗(yàn)證第繩三簽節(jié)《質(zhì)頭量姑風(fēng)衫險(xiǎn)栽管委理郵規(guī)蹈程》1卷.變壯更圓前框進(jìn)穿行部的云風(fēng)浪險(xiǎn)揮評(píng)漫估禁、超采斷取帽預(yù)魯防銹措鬧施祥等即行愁為殼本晴質(zhì)鼠上蟲(chóng)是疊預(yù)貢防梁偏毀差懸的賣行瞎為痛；境變榜更擠實(shí)槐施街后擇可鋒能群引低發(fā)嗽未蒸遇眠見(jiàn)波到遙的怪偏營(yíng)差系，逐需票要賣偏泉差棄調(diào)級(jí)查償和溝糾磚正陵措其施廉，列如鞋有寫必避要貝還擺應(yīng)禽在呼變稼更穗前龍后鵲開(kāi)飾展艙相層應(yīng)敲的憂確麻認(rèn)習(xí)和蛛驗(yàn)訂證積工發(fā)作旁；透變其更餓后犁的欲長(zhǎng)壺期鳴效涂果嘩確廣認(rèn)共也融應(yīng)敢進(jìn)筍行質(zhì)一午定辱的板現(xiàn)武象峰和航數(shù)咳據(jù)尼的潤(rùn)積塞累惠，籍通脫過(guò)流開(kāi)逆展寒質(zhì)差量游回厚顧和與啦分扭析尼加皺以肺進(jìn)脂一該步彼的金確皇認(rèn)招。第召三瓶節(jié)《質(zhì)饑量唉風(fēng)時(shí)險(xiǎn)乘管蓬理友規(guī)攜程》2尊.偏裳差搜處唉理漏本休質(zhì)證上鍵是鑼對(duì)側(cè)已且經(jīng)詳發(fā)伏生此的