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NeuralInterventionCompetitors—CoilsContentMedtronic-AXIUM?FamilyStryker-TargetFamilyMicroVention(TERUMO)Wallaby-Phenox(Avenir?)Medtronic-AXIUM?FAMILYCoilsAXIUMDETACHABLECOILSAXIUM

PRIME-FRAMEAXIUM

PRIME-SOFTAXIUM

PRIME-EXTRASOFTAXIUM

PRIME-MICROFXAXIUM?FAMILY

DELIVERYSYSTEMDETACHMENTMETHODAninstantmechanicaldetachmentwith99.7%provenreliability.FLEXIBLEVS.FIXEDJUNCTIONSBall&Socketdesign

allowsthecoilimplanttomoveindependentlyofthepusherresultinginlessenergybuildupandmicrocatheterkickout.FLEXIBLEVS.FIXEDJUNCTIONS

Axium?DetachmentSystemElectrolyticDetachmentSystemBallandsocketdesign

allowsthecoilimplanttomoveindependentlyofthepusherina

360°axialrotation

resultinginlessenergybuildupandmicrocatheterkickoutforsmoothcoildelivery.COMPAREAXIUM?PRODUCTSBYSOFTNESS,STABILITY,ANDOUTERDIAMETERSIZE.AXIUM?PRIMEFRAMEDETACHABLECOIL

AXIUM?

PRIMEFRAME:EXPERIENCEFLEXIBILITYANDSTABILITY.1.COMPLETEPROXIMALANDDISTALANCHORLOOPS

Closedloopsaredesignedtoreduceimplantherniation.2.OPENLOOPCONFIGURATION

Openloopsenhanceconfirmabilitytoaneurysmirregularities.3.UNIFORMLOOPDISTRIBUTIONANDDENSENECKCOVERAGE

Successiveloopschangedirectionevenlydistributingloopswithintheaneurysmandacrosstheneck.PROGRESSIVELYLARGEROUTERDIAMETERSAprogressiveouterdiametermatchedtotheimplantsizeoptimizesstabilityandvolumethroughouttheentirecoilline.CHARACTERISTICS

3DDiameter(mm)3–25Length(cm)6–50CoilO.D.(in)0.0115–0.0145Vol.(mm3)4.02–53.27AXIUM?PRIMESOFTANDEXTRASOFTDETACHABLECOILAXIUMPRIME?SOFTSOFTIMPLANTThinner.0015”primarywireandpreciselymatched.0115”O(jiān).D.tofillmorespace.RANDOMBREAKCOILDuetoitswindingpattern,whenthecoilencountersresistance,itcanmoreeasilydeflectandseekoutopenspaces.

AXIUMPRIME?EXTRASOFTGREATERPACKINGVOLUMELarger.0108”O(jiān).D.providesmorevolumeinafinishingcoil.EXTRASOFTIMPLANT0.0013“thinnerprimarywireleadstoasoftercoilpairedwithaprecisely-matchedO.D.tofillandfinishmorespace.RANDOMBREAKCOILDuetoitswindingpattern,whenthecoilencountersresistanceitcanmoreeasilydeflectandseekoutopenspaces.AXIUM?

PRIMESOFT

ENGINEEREDTOFILLAXIUM?

PRIMEEXTRASOFT

ENGINEEREDTOFINISHCHARACTERISTICS

ES-3DES-HelixSS-3DSS-HelixDiameter(mm)1–3.51–34–64–6Length(cm)2–101–106–206–20CoilO.D.(in)0.01080.01080.01150.0115Vol.(mm3)1.18–5.90.59–5.94.02–13.44.02–13.4EXPERIENCEPROVENSOFTNESSWhencomparedtotheTarget?360Nano?coil,theAxium?Prime(ExtraSoft)coilwas47%softer.TheAxium?Primecoilbrokeatlessforce,resultinginlessforce(g)

exertedagainstthe

aneurysmwall.國(guó)產(chǎn)彈簧圈型號(hào)直徑/mm長(zhǎng)度/cm圈直徑/in2D1.520.0110~0.01202D21/2/3/4/6/80.0110~0.01202D34/6/8/10/120.0110~0.01202D44/6/8/100.0125~0.0133型號(hào)直徑/mm長(zhǎng)度/cm圈直徑/in3D5/610/15/200.0125~0.01333D7/815/20/300.0125~0.01333D9/1020/300.0125~0.01333D11-20300.0129~0.01373D23/4/6/80.0110~0.01203D34/6/8/10/120.0110~0.01203D46/8/100.0125~0.01333D5/610/15/200.0125~0.01333D7/815/20/300.0125~0.01333D9/1020/300.0125~0.01333D11-20300.0129~0.0137AXIUM?MICROFX?DETACHABLECOILAXIUM?MICROFX?:EXPERIENCERAPIDFLOWREDUCTIONKEYBENEFITSOFAXIUM?MICROFX?COILSINTERLOCKEDSURFACEAREAPolymerfibers:

Axium?MicroFX?coilscontainPGLAornylonmicrofilamentsdesignedtoimpactflowreductionandacceleratethrombosis.LatticeFX?Technology:

LatticeFX?technologyprovidesaninterlockedsurfaceareaorscaffoldwhichorientscelladhesionandextracellulardeposition.ACCELERATEDTHROMBUSFORMATION

Enhancedthrombingenerationwithfilamentedcoilswhencomparedtobareplatinumcoilsandhigherthrombogenicitymaybebeneficial

insituationswhererapidocclusion

isneeded.VESSELORFISTULA

TAKEDOWN

Analternativetobareplatinumcoilsforarteriovenousfistulaeandotherneurovascularabnormalities.CHARACTERISTICS

3DHelixDiameter(mm)2–182–10Length(cm)2–401–30CoilO.D.(in)0.0115–0.01450.0115–0.0135Vol.(mm3)1.34–42.620.67–27.7

Stryker-TargetFamilyCoilsStryker-TargetEmbolizationCoils

Target3DTarget360TargetNanoTargetXLTarget3DStableframing.Target3DCoilsboastanaccuratedeploymentwithgeometricshapeforastableframe.Target360Conformabilityfromtheframetofinish.Target360Coilsfeatureanopenloopconfigurationdesignedforuniformdistribution,concentricfillingandneckcoverage.TargetNanoSmallandsoft.TargetNanoCoilsarepreciselyengineeredandextremelysoft.Our1mmand1.5mm360andhelicalcoilsprovideanewtreatmentperspective.TargetXLLargerandlonger.TargetXLCoilsfeature2xmorevolumepercoilthanTarget-10sizecoilsandupto50cminlength.AllareconsistentlydeliverablethroughanExcelsiorSL-10andExcelsiorXT-17Microcatheter.Target3DDETACHABLECOILSConsistentframingFeaturesandbenefitsTheTarget3Dcoilconfigurationisdesignedtoprovideaconsistentfoundationforsphericalspacesandwide-neckedaneurysms.ConsistentgeometricshapeForreliable,accuratedeploymentSecure,stablefoundationForastrongframeProvenperformanceSmoothandstabledeliveryfromtheProvenTargetCoilsplatformTarget360DETACHABLECOILSConformabilityfromframetofinishThe360shapeprovidesuniformdistribution,concentricfilling,andneckcoverage.Withconsistentlysmoothdeploymentandexceptionalmicrocatheterstability,thiscomplexcoilshapetechnologyisthegoldstandardforcoilingprocedures.OpenloopconfigurationFeaturesandbenefitsOpenloopsareengineeredforconformancetomultipleaneurysmshapeswhileminimizingcompartmentalizationOpencenterThe360shapeisdesignedtoseektheouterwallandleaveanopencenter,makingitidealforconcentricfilling2DdistalloopThefirst1.5loopsare25%smallerthanthestatedsecondarycoildiameter,designedtoreducecoilherniationTargetNanoDETACHABLECOILSBeyondsoftTargetNanoDetachableCoilsarethesoftestcoiltechnologyavailable.CombinedwithTargetCoil’sconsistentlysmoothdeploymentandexceptionalmicrocatheterstabilityresultsinanexperiencethatisBeyondSoft.Designedtotreatsmallspaces,TargetNanoCoil’sincrediblesoftnessdeliversincreasedconformabilityandshapeadjustment.SmallestSize:1mm×1cm(Loopdiameter×Length)FeaturesandbenefitsSoftnessStabilityConformability2xsofterthanTargetUltraCoilsAdvancedmicrocatheterstabilitySoftesttechnologyforsmallspacesTargetXLDETACHABLECOILSLargerandlongerTargetXLDetachableCoilsareavailableinawiderangeoflargerandlongersizes,toprovideadditionalvolumeandgreateraneurysmneckcoverage.LargestSize:24mm×50cm(Loopdiameter×Length)FeaturesandbenefitsLargercoilAverageof2Xgreatervolumepercoil,andupto66%longerlengthsSinglemicrocatheterWiderangeofsizes,allcompatiblewithExcelsior?SL-10?MicrocathetersProvenperformanceSmoothandstabledeliveryontheTargetCoilPlatformTarget360TargetHelicalTarget360Standard、Target360Soft、Target360Ultra、Target360NanoTarget

HelicalUltra、Target

HelicalNanoTargetXL360Standard、TargetXL360SoftTarget

XLHelicalMicroVention(TERUMO)CoilsMicroVention(TERUMO)CosmosComplex

CoilsProductBenefitsVersatileframingcoildesignedtoformastablebasketacrossvariousaneurysmmorphologiesVariableloopdesignallowsthecoiltobraceagainstaneurysmwallsandprovidestableframingacrosstheaneurysmneckAvailableinlongerlengthtoincreasenumberofloopsduringframingandprovidemorevolumetricfillingpercoilPariedwithV-TrakdeliverysystemwithexcellentperformancefromcoilintroductiontocoildeliveryanddetachmentStableEfficientControlledDeliveryandReliableDetachmentProductCompatibilityHeadwayDuo156Microcatheter,Headway17Microcatheter,Headway21MicrocatheterHyperSoft?

3D

&

HyperSoft?

Helical

Platinum

CoilsProductBenefitsExtrasoftfillingandfinishingcoilsavailableincomplex3DandhelicalconfigurationsExtraSoftCoildesignallowsforeasydeliveryandefficientfillingandfinishingwithoutdisruptingexistingcoilmassBroadOfferingControlledDeliveryandReliableDetachmentPariedwithV-TrakdeliverysystemwithexcellentperformancefromcoilintroductiontocoildeliveryanddetachmentAvailableinawiderangeof3DandhelicalsizesdesignedforprecisecoilplacementVFCSpecialty

CoilsProductBenefitsLoopandWaveDesignAninnovativecoildesignedtoseekoutandfillavailablespaceThisuniquedesignallowstheVFCembolizationcoiltoefficientlyseekoutandfillwithincomplexanatomiesVersatileRangeLongLengthsDuetotheloopandwavedesign,asingleVFC

embolizationcoilcancoverawiderangeofsizes;allowingasingleVFCembolizationcoiltoreplacemultipleconventionalcoilsontheshelf

IdealforquickandefficientfillingforocclusioninfistulasandvesselsacrificesHydroFillSpecialty

FillingCoilsProductBenefitsHelicalcoilwithexpansivehydrogeltechnologyEfficientFillingProvenHydrogelPerformanceSafeandEffectiveHydrogelexpansionprovidesupto50%increaseincoilvolume,maximizingocclusionforaneurysms,fistulae,andvesselsHydrogelcoreexpandstoprovideauniformscaffoldforneointimalgrowthandadditionalvolumetricfillingoftheaneurysmHydrogelcoilshaveshownsimilarsafetyprofilesasbareplatinumcoils,whiledemonstratinglowerratesofaneurysmrecurrenceandretreatmentaidedbytheprogressiveocclusionofaneurysmsovertimeHydroFrameHydrogel

EmbolicCoilsSafeandEffectiveEasytouseUniqueHydrogelTechnologyProductBenefitsFamilyofcomplexcoilswiththefamiliarityofbareplatinumandtheprovenbenefitsofhydrogeltechnology.Thecoilsareavailableinawiderangeofsizesforboththe10and18systems,providingversatilityforframingandfi

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