Sinapine-thiocyanate-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemESinapine(thiocyanate)(Standard)Cat.No.:HY-N0450RCASNo.:7431-77-8分子式:C??H??N?O?S分子量:368.45作用靶點(diǎn):P-glycoprotein;Cholinesterase(ChE)作用通路:MembraneTransporter/IonChannel;NeuronalSignaling儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Sinapine(thiocyanate)(Standard)是Sinapine(thiocyanate)的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Sinapinethiocyanate是一種從十字花科物種的種子中分離出來(lái)的生物堿。Sinapinethiocyanate具有抗炎，抗氧化，抗腫瘤，抗血管生成和放射防護(hù)作用。Sinapinethiocyanate還是一種乙酰膽堿酯酶(AChE)抑制劑，可用于研究阿爾茨海默癥，共濟(jì)失調(diào)，重癥肌無(wú)力和帕金森氏病。IC50&Target AChE[4],P-gp[1]REFERENCESGuoY,etal.SinapineasanactivecompoundforinhibitingtheproliferationofCaco-2cellsviadownregulationofP-glycoprotein.FoodChemToxicol.2014May;67:187-92.BoulghobraD,et,al.Sinapine,butnotsinapicacid,counteractsmitochondrialoxidativestressincardiomyocytes.RedoxBiol.2020Jul;34:101554.LiY,et,al.Sinapinereducesnon-alcoholicfattyliverdiseaseinmicebymodulatingthecompositionofthegutmicrobiota.FoodFunct.2019Jun19;10(6):3637-3649.YatesK,et,al.Determinationofsinapineinrapeseedpomaceextract:Itsantioxidantandacetylcholinesteraseinhibitionproperties.FoodChem.2019Mar15;276:768-775.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:02