孟魯司特對(duì)哮喘患兒血漿炎癥因子和臨床療效作用

1、孟魯司特對(duì)哮喘患兒血漿炎癥因子和臨床療效作用【中圖分類號(hào)】r256. 1【文獻(xiàn)標(biāo)識(shí)碼】b【文章編 號(hào)】1672-3783 (2013) 11-0593-01【摘要】目的對(duì)應(yīng)用孟魯司特對(duì)患有哮喘的患兒實(shí)施 治療的臨床效果進(jìn)行研究。方法抽取92例患有哮喘的患兒, 隨機(jī)分為對(duì)照組和治療組，平均每組46例。采用常規(guī)哮喘 治療方案對(duì)對(duì)照組患兒實(shí)施治療；在常規(guī)哮喘治療方案基礎(chǔ) 上加用孟魯司特鈉對(duì)治療組患兒實(shí)施治療。結(jié)果治療組患 兒的哮喘病情治療效果明顯優(yōu)于對(duì)照組；哮喘癥狀消失時(shí)間 和住院治療總時(shí)間明顯短于對(duì)照組；治療前后血漿炎癥因子 水平和fev1水平的改善幅度明顯大于對(duì)照組；藥物不良反 應(yīng)率明顯低于對(duì)照

2、組；治療后病情再次復(fù)發(fā)人數(shù)明顯少于對(duì) 照組。結(jié)論應(yīng)用孟魯司特對(duì)患有哮喘的患兒實(shí)施治療的臨 床效果非常明顯?！娟P(guān)鍵詞】孟魯司特鈉 哮喘治療血漿炎癥因子meng lusi , plasma inflammatory factors and clinical curative effect of children with asthmaabstract objective to apply meng lusi especially for the children with asthma to study the clinical effec t of t rea. tnient. met hods

3、 92 cases of children withasthma, were randomly divided into control group and treatment group, an average of 46 cases in each group. the conventional treatment of asthma treatment for children with the control group ； on the basis of conventional treatment of asthma and with meng lusi sodium in the

4、 treatment group with treatment resuits treatment group of children with asthma disease treatment effect is better than the control group； asthma symptoms disappear time and total time hospitalization obviously shorter than the control group ； before and after treatment plasma level of inflammatory

5、factor levels and fev1 has improved significantly greater than the control group； adverse drug reaction rate significantly lower than the control group ； iliness relapse again after treatment was significantly less than the control group. conclusionapplication of mengwith asthma therapy【key words 】l

6、usi especially for the children clinical effect is very obvious.meng lusi sodium asthma treatment plasma inflammatory factors兒童哮喘是由多種炎癥細(xì)胞和炎癥因子共同參與的一種以氣道高反應(yīng)性為主要特征表現(xiàn)的慢性氣道炎癥疾病 lo本次研究對(duì)患有哮喘的患兒在治療過(guò)程中應(yīng)用孟魯司 特鈉的臨床效果進(jìn)行研究?，F(xiàn)匯報(bào)研究過(guò)程如下。1資料和方法1.1 一般資料在2010年11月-2012年11月抽取92例患有哮喘的患 兒，隨機(jī)分為對(duì)照組和治療組。對(duì)照組患兒中男25例，女 21例；患兒年齡6-14歲，平均年齡(10.4±1.7)歲；患病 時(shí)間6個(gè)月-7年，平均患病時(shí)間(2.8±1.5)年；治療組患 兒中男27例，女19例；患兒年齡5-13歲，平均年齡 (10.2±1.8)歲；患病時(shí)間4個(gè)月-8年，平均患病時(shí)間 (2.9±1.3)年。本次研究對(duì)象在年齡、性別、患病時(shí)間等 自然指標(biāo)方面進(jìn)行組間比較p