MTT-Thiazolyl-Blue-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEMTTCat. No.: HY-15924CAS No.: 298-93-1Synonyms: Thiazolyl Blue; Thiazolyl Blue Tetrazolium Bromide;Methylthiazolyldiphenyl-tetrazolium bromide分式: CHBrNS分量: 414.32作靶點: Others作通路: Others儲存式: 4C, protect from light* In solvent : -8

2、0C, 6 months; -20C, 1 month (protect fromlight)溶解性數(shù)據(jù)體外實驗 DMSO : 32 mg/mL (77.23 mM)H2O : 0.88 mg/mL (2.12 mM; Need ultrasonic and warming)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.4136 mL 12.0680 mL 24.1359 mL5 mM 0.4827 mL 2.4136 mL 4.8272 mL10 mM

3、0.2414 mL 1.2068 mL 2.4136 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 MTT種泛于測量細胞增殖的劑。 MTT在活細胞中從 還原為紫甲。體外研究MTT is used in conjunction with rhodamine B to measure mitochondrial membrane potential. MTT-formazanis generated in mitochondria acts as a fluorescence quencher for rh

4、odamine that distributes across1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEmembranes of viable cells according to membrane potential. In the absence of mPMS, cellular reduction ofMTT is strong. MTT is membrane-impermeable when incorporated into large unilamellar liposomes, andtherefore it is ta

5、ken up by cells via endocytosis 1.戶使本產(chǎn)品發(fā)表的科研獻 J Med Chem. 2018 Dec 13;61(23):10814-10833. J Mol Cell Cardiol. 2015 May 28;85:168-177. Eur J Med Chem. 2018 Aug 5;156:21-42. Sci Rep. 2017 Sep 20;7(1):11935. J Immunol Res. 2018 Aug 2;2018:7498514.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Berridge MV, et al. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev.2005;11:127-52.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3