Rhynchophylline _NF-κB 抑制劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemERhynchophyllineCat. No.: HY-N0387CAS No.: 76-66-4分式: CHNO分量: 384.47作靶點(diǎn): NF-B作通路: NF-B儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 33.33 mg/mL (86.69 mM; Need ultrasonic)H2O : 40% PEG300

2、5% Tween-80 45% salineSolubility: 2.5 mg/mL (6.50 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (6.50 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 鉤藤堿 (Rhyncholphylline)從鉤藤中分離到的種物堿類化合物，具有很的物活性，被泛于抗炎、神經(jīng)保護(hù)等的研究。戶使本產(chǎn)品發(fā)表的科研獻(xiàn) Mol

3、Cell Biochem. 2019 Aug 16.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Dan Yuan, et al. Anti-inflammatory effects of rhynchophylline and isorhynchophylline in mouse N9 microglial cells and the molecularmechanism. International ImmunopharmacologyVolume 9, Issues 1314, Decembe

4、r 2009, Pages 154915542. Houcai Huang, et al. Neuroprotective Effects of Rhynchophylline Against Ischemic Brain Injury via Regulation of the Akt/mTOR andTLRs Signaling Pathways. Molecules 2014, 19 (8): 11196-11210; doi:10.3390/molecules1908111963. Tai-Hyun Kang, et al. Protective effect of rhynchoph

5、ylline and isorhynchophylline on in vitro ischemia-induced neuronal damage in thehippocampus: putative neurotransmitter receptors involved in their action. Life SciencesVolume 76, Issue 3, 3 December 2004, Pages3313434. Kinzo Matsumoto, et al. Suppressive effects of isorhynchophylline on 5-HT2A receptor function in the brain: Behavioural andelectrophysiological studies. European Journal of PharmacologyVolume 517, Issue 3, 11 July 2005, Pages 191199McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3