S-plus-Marmesin-plus-Marmesin-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemES-(+)-MarmesinCat. No.: HY-N2176CAS No.: 13849-08-6Synonyms: (+)-Marmesin; (S)-Marmesin分式: CHO分量: 246.26作靶點(diǎn): COX; 5-Lipoxygenase作通路: Immunology/Inflammation; Metabolic Enzyme/Protease儲存式: Powder -20C 3 years4C 2 yearsIn solvent

2、-80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 2 mg/mL (8.12 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 4.0607 mL 20.3037 mL 40.6075 mL5 mM 0.8121 mL 4.0607 mL 8.1215 mL10 mM - - -請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 S-(+)-Marmesin種天然的素，具有 COX-2/5

3、-LOX 雙重 抑制作。IC50 & Target COX-2 5-Lipoxygenase體外研究S-(+)-Marmesin (+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 0.5 M, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary1/2 Master of Small Molecules 您邊的抑制劑師www.M

4、edChemEmetabolism 1. S-(+)-Marmesin (+)-marmesin) shows COX-2/5-LOX dual inhibitory activity 2.REFERENCES1. Larbat R, et al. Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase offuranocoumarin biosynthesis. J Biol Chem. 2007 Jan 5;282(1):542-54.

5、 Epub 2006 Oct 26.2. Kim JS, et al. Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity. Arch Pharm Res. 2006Aug;29(8):617-23.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58955