靶向分子適配文獻總結(jié)報告課件

1、Aptamer 應(yīng)用文獻總結(jié)靶向藥物傳遞 Aptamer-functionalized PEGPLGA nanoparticles for enhanced antiglioma drug delivery (2011,Biomaterials)AS1411 DNA aptamer 5-TTGGTGGTGGTGGTTGTGGTGGTGGTGG-3膠質(zhì)瘤細胞（C6 glioma cell ）1、 PEGylated Anti-MUC1 Aptamer-Doxorubicin Complex or Targeted Drug Delivery to MCF7 Breast Cancer Cells

2、（2011，Macrolecular Bioscience）MUC1 DNA aptamer乳腺癌細胞（MCF7）2、 Tumor targeted quantum dot-mucin 1 aptamer-doxorubicin conjugate for imaging and treatment of cancer（2011, Journal of Controlled Release）MUC1 DNA aptamer 5-GCA-GTT-GATCCT-TTG-GAT-ACC-CTG-G-3卵巢癌細胞（ovarian ） 3、 Novel Aptamer-Nanoparticle Bioc

3、onjugates Enhances Delivery of Anticancer Drug to MUC1-Positive Cancer Cells In Vitro（2011，PolS ONE） A modified aptamer S2.2-spacer : 5-GCA GTT GAT CCT TTG GAT ACC CTG GTT CCC TTC CTT CTC TCT TCC TCT CTC CTT CTC TCT TCC TCT CTC CTT C-3 乳腺癌細胞（MCF-7） 4、 Aptamer-Conjugated DNAIcosahedral Nanoparticles

4、As a Carrier of Doxorubicin for Cancer Therapy（2011，ACS NANO）MUC1 aptamerMCF-75、 A liposome-based nanostructure for aptamer directed delivery（2010, Chem. Commun） Sgc8 T淋巴細胞急性白血病細胞（CEM)7、8、 Nanoparticle-Aptamer Bioconjugates: A New Approach for Targeting Prostate Cancer Cells （2010, Chem. Commun） A10

5、 PMSM 前列腺癌細胞（PC3） Quantum Dot-Aptamer Conjugates forSynchronous Cancer Imaging, Therapy, and Sensing of Drug Delivery Based on Bi-Fluorescence Resonance Energy Transfer（2007，NANO LETTERS）A10 PMSM前列腺癌細胞（LNCaP cell）9、10、 Aptamer Biosensor Based on Fluorescence Resonance Energy Transfer from Upconverti

6、ng Phosphors to Carbon Nanoparticles for Thrombin Detection in Human Plasma（2011,Analytical Chemistry） thrombin aptamer (5-NH2- GGTTGGTGTGGTTGG-3) 凝血酶量子點、上轉(zhuǎn)換熒光檢測靶向光熱治療、光動力治療 Gold Nano-Popcorn Attached SWCNT Hybrid Nanomaterial for Targeted Diagnosis and Photothermal Therapy of Human Breast Cancer Ce

7、lls（2011，ACS APPLIED MATERIALS &INTERFACES） S6 aptamer乳腺癌細胞（SK-BR-3） 12、 Regulation of Singlet Oxygen Generation Using Single-Walled Carbon Nanotubes（2008，JACS） B細胞淋巴瘤細胞Romas cell 13、14、 Aptamer-Based Tumor-Targeted Drug Delivery for Photodynamic Therapy（ACS NANO） AS1411 : 5GGTGGTGGTGGTTGTGG TGGTGG

8、TGG-3MCF-7 靶向基因治療 Molecular imaging of a cancer-targeting theragnostics probe using a nucleolin aptamer- and microRNA-221 molecular beacon-conjugated nanoparticle（2012，Biomaterials） AS1411 5-GGTGGTGGTGGTTGTGGTGGTGG TGG3 膠質(zhì)瘤細胞（C6 cell）15、Stimuli-responsive releasing of goldnanoparticles and liposomes from aptamerfunctionalized hydrogel（2011，Nanotechnology） 腺苷17、 A hybrid particlehydrogel composite for oligonucleotide-mediated pulsatile protein release（2010，Soft Matter） anti