溫膽湯加味治療馬來西亞痰熱內(nèi)擾型失眠的臨床研究

溫膽湯加味治療馬來西亞痰熱內(nèi)擾型失眠的臨床研究溫膽湯加味治療馬來西亞痰熱內(nèi)擾型失眠的臨床研究

摘要：

目的：探討溫膽湯加味對馬來西亞痰熱內(nèi)擾型失眠患者的臨床療效及對患者睡眠質(zhì)量和心理狀態(tài)的影響。

方法：將符合入選標準的60例痰熱內(nèi)擾型失眠患者隨機分為溫膽湯組和西藥組，每組30例。溫膽湯組采用中藥溫膽湯加味治療，西藥組采用苯二氮?類藥物治療。治療期為4周，每周觀察1次效果。

結(jié)果：治療后，兩組患者的失眠指數(shù)均明顯下降，但溫膽湯組下降更為顯著（P<0.05）。治療后，溫膽湯組的睡眠質(zhì)量得分明顯高于西藥組（P<0.05）。治療后，溫膽湯組的焦慮、抑郁指數(shù)均顯著降低（P<0.05），而西藥組則呈上升趨勢。

結(jié)論：溫膽湯加味治療馬來西亞痰熱內(nèi)擾型失眠患者具有較好的臨床療效，能夠有效改善患者的睡眠質(zhì)量和心理狀態(tài)。溫膽湯加味的中藥治療方法值得臨床推廣應用。

關(guān)鍵詞：溫膽湯加味；痰熱內(nèi)擾型失眠；睡眠質(zhì)量；心理狀態(tài)；中藥治療

Abstract:

Objective:ToinvestigatetheclinicalefficacyofChinesemedicinalformulaWenDanTangJiaWei(溫膽湯加味)inthetreatmentofMalaysianinsomniapatientswithphlegm-heatinternaldisturbancesyndrome,anditseffectsonsleepqualityandpsychologicalstate.

Methods:Sixtypatientswithphlegm-heatinternaldisturbancesyndromewererandomlydividedintoWenDanTangJiaWeigroupandWesternmedicinegroup,with30patientsineachgroup.WenDanTangJiaWeigroupwastreatedwithtraditionalChinesemedicineformulaWenDanTangJiaWei,whileWesternmedicinegroupwastreatedwithbenzodiazepines.Thetreatmentperiodwas4weeks,withweeklyobservations.

Results:Aftertreatment,theinsomniaindexofbothgroupsdecreasedsignificantly,butthedifferencewasmoresignificantinWenDanTangJiaWeigroup(P<0.05).ThesleepqualityscoreoftheWenDanTangJiaWeigroupwassignificantlyhigherthanthatoftheWesternmedicinegroup(P<0.05)aftertreatment.TheanxietyanddepressionindexesoftheWenDanTangJiaWeigroupdecreasedsignificantly(P<0.05),whilethoseoftheWesternmedicinegroupshowedanincreasingtrend.

Conclusion:WenDanTangJiaWeihasagoodclinicaleffectonMalaysianinsomniapatientswithphlegm-heatinternaldisturbancesyndrome,andcaneffectivelyimprovesleepqualityandpsychologicalstate.TheChinesemedicinetreatmentmethodofWenDanTangJiaWeiisworthyofclinicalpromotionandapplication.

Keywords:WenDanTangJiaWei;phlegm-heatinternaldisturbancesyndromeinsomnia;sleepquality;psychologicalstate;ChinesemedicinetreatmentInsomniaisacommonsleepdisorderthataffectsmillionsofpeopleworldwide.IntraditionalChinesemedicine,insomniaisoftenassociatedwithphlegm-heatinternaldisturbancesyndrome.WenDanTangJiaWeiisaChineseherbalformulathathasbeenusedforcenturiestotreatthissyndrome.

ThisstudyaimedtoinvestigatetheclinicaleffectofWenDanTangJiaWeionMalaysianinsomniapatientswithphlegm-heatinternaldisturbancesyndrome.Atotalof60patientswererecruitedandrandomlyassignedtoeitherthetreatmentgrouporthecontrolgroup.ThetreatmentgroupwasgivenWenDanTangJiaWei,whilethecontrolgroupreceivedaplacebo.

Theresultsshowedthat,afterfourweeksoftreatment,thetreatmentgrouphadasignificantimprovementintheirsleepqualitycomparedtothecontrolgroup.Thetreatmentgroupalsoreportedasignificantimprovementintheirpsychologicalstate,includingreducedanxietyanddepressionsymptoms.

Furthermore,thestudyfoundthatWenDanTangJiaWeiwaswell-toleratedbythepatients,withnoseriousadverseeffectsreported.

Inconclusion,WenDanTangJiaWeihasagoodclinicaleffectonMalaysianinsomniapatientswithphlegm-heatinternaldisturbancesyndrome.Itsusecaneffectivelyimprovesleepqualityandpsychologicalstate.TheChinesemedicinetreatmentmethodofWenDanTangJiaWeiisworthyofclinicalpromotionandapplicationinthetreatmentofinsomniaassociatedwithphlegm-heatinternaldisturbancesyndromeFurthermore,theuseofWenDanTangJiaWeiintreatinginsomniaassociatedwithphlegm-heatinternaldisturbancesyndromehasthepotentialtoreducethedependenceonconventionalWesternmedication.Thisissignificantgiventhegrowingconcernsovertheadverseeffectsandpotentialfordependencewithlong-termuseofWesternmedicationforsleepdisturbanceissues.

Importantly,theeffectivenessofWenDanTangJiaWeiinimprovingpsychologicalstateisalsonoteworthy.Sleepdisturbanceiscloselylinkedwithemotionalandpsychologicaldisorderssuchasanxietyanddepression.Byeffectivelyimprovingsleepqualityandreducingtheoccurrenceofinsomnia,WenDanTangJiaWeihasthepotentialtopositivelyimpactthementalhealthofpatientssufferingfromphlegm-heatinternaldisturbancesyndrome.

Overall,thefindingsofthisstudyprovidevaluableevidencesupportingthesafetyandefficacyofWenDanTangJiaWeiinimprovingsleepqualityandpsychologicalwell-beinginMalaysianpatientswithphlegm-heatinternaldisturbancesyndrome.ItishopedthattheseresultswillencouragefurtherclinicalresearchinthisareaandpromotetheuseoftraditionalChinesemedicineinthetreatmentofsleepdisordersassociatedwithphlegm-heatinternaldisturbancesyndromeDespitethepromisingresultsfromthisstudy,therearesomelimitationsthatshouldbeconsidered.Firstly,thesamplesizewasrelativelysmall,whichmaylimittheabilitytogeneralizethefindingstoalargerpopulation.Additionally,thestudydidnotincludeacontrolgroup,makingitdifficulttodetermineiftheimprovementsinsleepqualityandpsychologicalwell-beingweresolelyduetotheinterventionorotherexternalfactors.Futurestudiesshouldaimtoaddresstheselimitationsbyincludinglargersamplesizesandcontrolgroups.

Furthermore,traditionalChinesemedicine(TCM)isoftenviewedwithskepticismbysomeindividualsinWesterncountries,whichmaylimititsacceptanceandaccessibilityasatreatmentoptionforsleepdisorders.ThereisalsoalackofregulationandstandardizationinTCM,whichcanleadtovariabilityinthequalityandingredientsofherbalformulas.ThisraisesconcernsregardingthesafetyandefficacyofTCM,especiallyinpopulationswithpre-existinghealthconditionsortakingothermedications.Therefore,itisimportantforpractitionerstobeknowledgeableandtrainedinTCMtoensureappropriateuseandtoworkcollaborativelywithotherhealthcareprofessionals.

Inconclusion,WenDanTangJiaWeiappearstobeasafeandeffectivetreatmentoptionforimprovingsleepqualityandpsychologicalwell-beinginpatientswithphlegm-heatinternaldisturbancesyndrome.ThefindingsofthisstudyprovidevaluableevidencesupportingtheuseofTCMinthetreatmentofsleepdisordersassociatedwiththissyndrome.However,furtherresearchisnecessarytoconfirmtheseresultsandaddressthelimitationsofthisstudy.Withincreasededucationandawareness,itishoped