脊髓血管母細(xì)胞瘤的外科治療課件

TreatmentofSpinalHemangioblastomaCushing'snotes869-1939PathologyTUMOURSOFTHEMENINGESTumoursofmeningothelialcells鐘密分H分Mesenchymaltum。urs血管母細(xì)胞瘤1993,2000PrimarymelanocyticlesionsOtherneoplasmsrelatedtothemeninges91612007WHOllⅢⅣMeningealtumoursClassificationMeningiomaAtypicalmeningiomaAnaplastic/malignantmeningiomaAnaplastichaemangiopericytomaHemangioblastoma感Left:Thevascularlyrichareashowstypicalhemangioblastomacomposedofdelicatevascularchannelswithinterstitialstromalcells(HEX400)Right:AdditionalimmunohistochemicaldeterminationusingS100proteinrevealingamarkedpositivestaininthenerverootandinafewpartsofthetumorscellularcomponents(HEX400Epidemiology成人脊髓腫瘤發(fā)生率髓外腫瘤髓內(nèi)腫瘤(2/3的病例)%(1/3的病例)神經(jīng)鞘瘤40室管膜瘤脊膜瘤40星形細(xì)胞瘤40終絲室管膜瘤15血管母細(xì)胞瘤5其他其他10摘自YoumansNeurologicalSurgery(第5版)GeneticsSporadicalcomponentofvonHippel-Lindaudisease(20%to30%)【常顯,3p25-26】m1)交清楊俊,王貴懷脊血管母細(xì)胞稻的顯微手術(shù)治療[1甲國微侵襲神經(jīng)外科2010,15(3):115-1172]楊樹源,楊新宇,洪國良,外科手術(shù)治療174例脊髓髓內(nèi)腫瘤[.內(nèi)蒙古民族大學(xué)學(xué)報,2009155):104-1093]單永治,凌鋒,李萌,等.脊髓血管母細(xì)胞瘤的診斷與治療].中國臨床神經(jīng)外科雜志,20049(1):19-21丁興華,車曉明,徐啟武.166例脊髓髓內(nèi)腫瘤的臨床資料分析中國微侵襲神經(jīng)外科雜志20049(9)388-3905]薛懷安,張遠(yuǎn)征,程東源,等.600例脊髓內(nèi)腫瘤顯微手術(shù)治療[解放軍醫(yī)學(xué)雜志,200328(2):1896]YangYM,WangDM,JiangHZ,TreatmentofspinalcordHemangioblastomabymicrooperationscombinedwithembolization[J].ZhonghuaYiXueZazhi,2008,88(19):1309-1312[7]崔大明,車曉明,徐啟武,等.脊髓血管母細(xì)胞瘤的診斷和治療[]中華醫(yī)學(xué)雜志2007,87(5)308-310多中心回顧性分析LocationCervcal13對描述發(fā)生部位的361個血管母細(xì)胞瘤進行統(tǒng)計T-L1600150200250Lumbar63.9%Vs36.1%年齡8-72y,平均347yRelationship