【神外2】南方醫(yī)院膠質(zhì)瘤治療理念與手術(shù)中文版

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1、南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Treatment concept and surgical resection in glioma Nanfang Hospital Nanfang Glioma Center Guangzhou China Songtao Qi 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Nanfang Glioma Center Patients with glioma undergoing surger

2、y: 180-200 Patients with recurrent glioma: 40-50 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Age standardized prevalence of primary brain tumor is 22.52 per million for all populations and gliomas account for 31.1% in those aged 2059 years. Based on the Chinese Glioma Geno

3、me Atlas (CGGA) statistics, malignant gliomas have an unfavorable prognosis with median overall survival times (OS) of 78.1 months for low-grade gliomas (WHO Grade II), 37.6 months for anaplastic gliomas and 14.4 months for GBMs. Epidemiology and survival 1 T. Jiang, G.F. Tang, Y. Lin, X.X. Peng, X.

4、 Zhang, X.W. Zhai, et al., Prevalence estimates for primary brain tumors in China: a multi-center cross-sectional study, Chin. Med. J. 124 (17) (2011) 25782583 2 P. Yang, Y. Wang, X. Peng, G. You, W. Zhang, W. Yan, et al., Management and survival rates in patients with glioma in China (20042010): a

5、retrospective study from a single-institution, J. Neurooncol. 113 (2) (2013) 259266, doi:10.1007/s11060-013- 1103-9. 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Treatment Concept Chemotherapy （Targeted therapy） Radiotherapy Surgery Surgery: The first step in glioma treatme

6、nt; also the key step in the treatment! 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Surgical Resection Super-radical resection; Protection of neurologcial function and quality of life. 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Surgical Resectio

7、n Extent of tumor resection histology performance status molecular markers (1p19q co-deletion, IDH status, MGMT , ATRX mutation) Prediction of patient outcome Improve OS and PFS, symptom management, and time to malignant transformation in low- and high-grade gliomas 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfa

8、ng Glioma CenterNanfang Glioma Center Surgical Resection 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Surgical Resection 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Surgical Resection we performed a review of the literature of the last seven years

9、, finding a total of 28 studies and 2279 patients who underwent second surgery; Extent of resection at reoperation improves overall survival, even in patients with subtotal resection at initial operation. 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center The concept of surgery S

10、uper-radical resection? 20-years experience of Nanfang Hospital Aggressive surgery Lobe resection Frontal lobe Temporal lobe Occipital lobe Cerebellum Brain stem Thalamus Sellar region Functional area Pineal region Carve the tumor T1 C+、T2、FLAIR T1 C+ 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma Cente

11、rNanfang Glioma Center Cases reports 1 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 1 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 病理取材七分法病理取材七分法 Cases reports 1 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center A

12、 B C Cases reports 1 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 1 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 1 4 weeks after concurrent chemoradiotherapy 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Gliom

13、a Center Cases reports 1 4 weeks after concurrent chemoradiotherapy 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 1 GBM，2013-3-22，Preoperative GBM，2015-12-08，33 months postoperatively 2015-12-08 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Ce

14、nter Cases reports 2 Preoperative Postperative 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 2 Postperative 3 years postperatively Anaplastic astrocytomas 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 3 Preoperative Postop

15、erative 2013-2-6 surgery GBM 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 3 4 months postperatively 1.5 years postperatively 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 2 years postperatively 2.5 years postperatively 20

16、09 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports Preoperative: Bedridden state（臥床狀態(tài)）（臥床狀態(tài)） 3 years Postoperatively 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 4 Preoperative Postperative 2013-12 GBM 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中

17、心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 4 Preoperative Postoperative 2 years postoperatively GBM 2 years after surgery 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 5 1 day postoperativelyPreoperative Preoperative Preoperative 1 day postopera

18、tively GBM 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 5 Recurrence？ Pseudo- progression？ PET: no hypermetabolism Good mental state CCRT 1 months postoperatively 1 months postoperatively 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center C

19、ases reports 5 3 months Po1.5 years Po 3 months Po 9 months Po 9 months Po 1.5 years Po 2 years Po 2 years Po 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 5 3 years Po 1 years Po 3 years Po5 years Po 7 years Po 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma Center

20、Nanfang Glioma Center Cases reports 6 Preoperative Postoperative GBM OS= 2.5 years 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Confusion? PFS 7 years OS= 2.5 years 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 7 2014-4 GBM Preoperativ

21、e Postoperative 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 8 Postoperative Preoperative 2014-5 GBM 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 9 (Recurrent) 2011-1 anaplastic oligodendrogliomas WHO III Preoperative 0.

22、5 years Po 1 years Po 1.5 years Po 2 years Po 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 2.5 years Po3 years Po 3.5years Po4 years Po GBM Cases reports 9 (Recurrent) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 10 (Residual tumor) R

23、esidual tumor? 2016-5-1 2016-5-1 2016-5-21 2016-5-21 2016-5-4 2016-5-4 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 10 (Residual tumor) 我院術(shù)前我院術(shù)前 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 10 (Residual tumor) 2 days Po

24、2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 10 (Residual tumor) 2016-5-25 2016-5-25 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Male, 22 years old, headache with nausea and vomiting. MRI: lesions in the left thalamus . 2016-4-6 surg

25、ery at the local hospital. Cases reports 11 (Residual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 2016-4-8 2016-4-13 2016-4-15 Cases reports 11 (Residual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center MRI 2016-4-8 Cases reports 11 (Res

26、idual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Awake postoperatively， Aphasia ，Right limb: 0, left limb: normal 4-12 Pathology： Anaplastic astrocytoma （WHOIII） GFAP(+)，Olig2(+)，Ki67(40%)，P53(+)，MGMT(-)，IDH1(-)。 4-18 Loss of consciousness ， Deep coma ， bilateral m

27、ydriasis , Cyanosis, blood oxygen satura low，CPR。 4-24 Nanfang Hospital Cases reports 11 (Residual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 2016-4-25 Preoperative MRI Cases reports 11 (Residual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Gliom

28、a Center 2016-4-27 POPPEN approach plus occipital ostomy Cases reports 11 (Residual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 11 (Residual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center MRI 1 day postoperatively Cases r

29、eports 11 (Residual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 11 (Residual tumor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 1 day postoperatively 1 week postoperatively 2 week postoperatively Cases reports 11 (Residual tu

30、mor) 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 12 Preoperative Postperative Anaplastic astrocytomas 1 year Po 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 13 MCA and its branches preserved after tumor removal. 2009 南方

31、醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 13 Anaplastic astrocytomas 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 14 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 14 Tumor CNII Car.A CN

32、II Car.A 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 14 To isolate the tumor in the internal carotid artery upper space Tumor was totally removed after isolation 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 14 Tumor was

33、 removed Pituitary stalk was preserved 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 14 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 15 Cases reports 15 腫瘤呈彌漫性生長(zhǎng)，右側(cè)視神經(jīng)完全被侵犯 T T CN IICN II 顯露第三腦室腔 ACoAACoA T T A2A2 A1A1 3

34、3rd rd ventricle ventricle 顯露垂體柄 Pituitary Pituitary stalkstalk DiencephalicDiencephalic membrane of membrane of Liliequist Liliequist Dorsum Dorsum sellaesellae Car.ACar.A Pilocytic astrocytoma 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 15 Preoperative Post

35、operative 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 2014-9-22 POPPEN approach Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 16

36、2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Occip.Lobe Tent Falx Galen .V AEPG Tumor Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 手術(shù)視頻1 Cases

37、reports 16 手術(shù)視頻2 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 16 GBM 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版

38、權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 0.5 year Po1 year Po1.5 years Po 2 years Po 0.5 year Po1 year Po1.5 years Po 2 years Po Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center PFS 2 years Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Gli

39、oma CenterNanfang Glioma Center Cases reports 16 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 17 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 17 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Case

40、s reports 17 Video 1 Video 2 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 17 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 17 Astrocytoma WHO II 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases

41、 reports 17 1 day postoperatively1 week postoperatively 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 18 Stiffness 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Exposing tumorPOPPEN approach 分離腫瘤分離腫瘤 Cases reports 18 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有

42、南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 18 9 days after surgery 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 18 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 18 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfan

43、g Glioma CenterNanfang Glioma Center Cases reports 18 1.5 months Po 4 months Po6 months Po10 months Po15 months Po 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 2013-4-92014-3-2 47歲男性，歷時(shí)歲男性，歷時(shí)1年，全國(guó)多方求醫(yī)未果，腫瘤逐漸增大年，全國(guó)多方求醫(yī)未果，腫瘤逐漸增大 Cases reports 19 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Na

44、nfang Glioma CenterNanfang Glioma Center 吸引器吸引器顯微剪刀顯微剪刀激光刀激光刀顯微剝離子的使用顯微剝離子的使用 video 手術(shù)時(shí)間2014-3-7 Cases reports 19 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Tumor 3cm，anaplastic astrocytoma 1 day postoperatively Cases reports 19 PreoperativePostoperative 2009 南方醫(yī)院神經(jīng)外科

45、版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 延髓膠質(zhì)瘤術(shù)后延髓膠質(zhì)瘤術(shù)后1周周 video Cases reports 19 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 2014-9-15，術(shù)后半年，術(shù)后半年 2014-9-15，6 months postoperatively Cases reports 19 Recurrence or Pseudo- progression？ 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)

46、瘤中心 Nanfang Glioma CenterNanfang Glioma Center 2014-12-5，術(shù)后，術(shù)后9個(gè)月個(gè)月 Walking difficulty breathing difficulties Numbness of the body Cases reports 19 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center 2014-12-8，第二次手術(shù)，第二次手術(shù) video Cases reports 19 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang

47、Glioma CenterNanfang Glioma Center Heart almost stopped When operation Cases reports 19 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Preoperative MRI Before the second surgery Cases reports 19 Postoperative MRI after the second surgery 2009 南方醫(yī)院神經(jīng)外科版權(quán)所有南方腦膠質(zhì)瘤中心 Nanfang Glioma CenterNanfang Glioma Center Cases reports 19 Posto

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