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1、分子生物學(xué)數(shù)據(jù)庫(kù)大全一、核酸及其相關(guān)數(shù)據(jù)庫(kù)1.核酸序列數(shù)據(jù)庫(kù) BIOSINO 我國(guó)的核酸序列公共數(shù)據(jù)庫(kù) 1.核酸序列數(shù)據(jù)庫(kù) BIOSINO 我國(guó)的核酸序列公共數(shù)據(jù)庫(kù) EMBL - EMBL Nucleotide sequence database (EBI) * GenBank - GenBank Nucleotide Sequence database (NCBI) * DDBJ - DNA Data Bank of Japan * dbEST - Database of Expressed Sequence Tags (NCBI) dbSTS - Database of Seq
2、uence Tagged Sites (NCBI) 2.基因組及相關(guān)數(shù)據(jù)庫(kù) Genomic Databases GenomeWeb(HGMP) - A catalogue of useful Web sites for Genomics with a set of collections of genome databases GSDB - Genome Sequence database (NCGR) GOLD - Genomes On-line db 一些數(shù)據(jù)庫(kù)的直接鏈接 DOGS - Database of Genome Sizes Genomics web si
3、te (John Wiley & Sons Ltd) (The Genomics website at Wiley is a new and DYNAMIC resource for the genomics community, offering FREE special feature articles and new information EACH MONTH.) HUGO - HUman Genome Organization3.核酸三維結(jié)構(gòu)數(shù)據(jù)庫(kù) NDB - Nucleic Acid Databank (3D structures) BNASDB - Nucleic aci
4、d structure db from University of Pune 4 轉(zhuǎn)基因數(shù)據(jù)庫(kù)(Transgenics) Cre Transgenic Database - Cre transgenic mouse lines Transgenic/Targeted Mutation Database - Information on transgenic animals and targeted mutations5.其他 AsDb - Aberrant Splicing db ACUTS - Ancient conserved untranslated DNA sequences db C
5、odon Usage Db - The frequency of codon use in each organism is made searchable through this World Wide Web site. EPD - Eukaryotic Promoter db HOVERGEN - Homologous Vertebrate Genes db IMGT - ImMunoGeneTics db Mirror at EBI ISIS - Intron Sequence and Information System RDP - Ribosomal db Projec
6、t gRNAs db - Guide RNA db PLACE - Plant cis-acting regulatory DNA elements db PlantCARE - Plant cis-acting regulatory DNA elements db sRNA db - Small RNA db ssu rRNA - Small ribosomal subunit db lsu rRNA - Large ribosomal subunit db 5S rRNA - 5S ribosomal RNA db tmRNA Website tmRDB - tmRNA dB tRNA -
7、 tRNA compilation from the University of Bayreuth uRNADB - uRNA db RNA editing - RNA editing site RNAmod db - RNA modification db TelDB - Multimedia Telomere Resource TRADAT - TRAnscription Databases and Analysis Tools Subviral RNA db - Small circular RNAs db (viroid and viroid-like) MPDB - Molecula
8、r probe db OPD - Oligonucleotide probe db VectorDB - Vector sequence db二、基因表達(dá)數(shù)據(jù)庫(kù) ASDB - Protein products and expression patterns of alternatively-spliced genes Axeldb - Gene expression in Xenopus BodyMap - Human and mouse gene expression data EpoDB - Genes expressed in vertebrate RBC FlyView - Droso
9、phila development and genetics Gene Expression Database (GXD) - Mouse gene expression and genomics Kidney Development Database - Kidney development and gene expression MAGEST - Ascidian (Halocynthia roretzi) gene expression patterns Mouse Atlas and Gene Expression Database - Spatially-mapped gene ex
10、pression data PEDB - Normal and aberrant prostate gene expression Tooth Development Database - Gene expression in dental tissue TRIPLES - TRansposon-Insertion Phenotypes, Localization and Expression in Saccharomyces三、蛋白質(zhì)及其相關(guān)數(shù)據(jù)庫(kù)1.蛋白質(zhì)序列和相關(guān)數(shù)據(jù)庫(kù) SWISS-PROT - SWISS-PROT annotated protein sequence db PIR-i
11、nternational -The Protein Information Resource (protein sequence) MIPS - Martinsried institute for protein sequence and homology data and yeast genome information PROSITE - PROSITE dictionary of protein sites and patterns InterPro - Integrated Resources of Proteins Domains and Functional Sites BLOCK
12、S - BLOCKS db DOMO - Protein domain db (Automatically generated) Pfam - Protein families db (HMM derived) Mirror at Sanger PRINTS - Protein Motif fingerprint db ProDom - Protein domain db (Automatically generated) PROTOMAP - An automatic hierarchical classification of SWISS-PROT proteins SBASE - SBA
13、SE domain db (Protein domain sequence library) SMART - Protein signalling and extracellular domain patterns (Simple Modular Architecture Research Tool) ProClass - Protein sequence alignments and curation of protein families Kabat - Kabat db of protein of immunological interest PMD - Protein Mutant d
14、b2.蛋白質(zhì)三維結(jié)構(gòu)和相關(guān)數(shù)據(jù)庫(kù) PDB - Protein Data Bank Mirrors in EBI BioMagResBank - Repository for data on proteins, peptides, and nucleic acids from NMR spectroscopy SWISS-MODEL Repository - Automatically generated protein models db ModBase - Db of comparative protein structure models CATH - UCL BSM structural
15、 classification of proteins SCOP - Structural classification of proteins Mirror at USA | Israel | Singapore | Australia Mol_R_Us - Molecules R Us, browser for PDB BMM Domain Server - Biomolecular Modelling Laboratory (ICRF) protein domain server PRESAGE - Collaborative resource for structural genomi
16、cs ReLiBase - Receptor/ligand complexes db Mirror in USA TOPS - Protein topology atlas CCDC - Cambridge Crystallographic Data Center (Cambridge Stuctural Db (CSD) HSSP - Homology-derived secondary structure of proteins db SWISS-3DIMAGE - 3D images of proteins and other biological macromolecules BioI
17、mage - Biological image db (contains imaging data on macromolecules) 3.蛋白質(zhì)二維凝膠電泳數(shù)據(jù)庫(kù) WORLD-2DPAGE - A complete index of 2D-PAGE db and servers Phoretix links - Phoretix page of links to 2D gel db 4.信號(hào)傳導(dǎo)及蛋白質(zhì)-蛋白質(zhì)相互作用相關(guān)數(shù)據(jù)庫(kù) DIP - Db of Interacting Proteins INTERACT - Protein-Protein interaction db ProNet
18、 - Protein-Protein interaction db CANSITE - Signal Transduction's Web SPAD - Signaling pathway db CSNDB - Cell Signaling Networks db 5.DNA和蛋白質(zhì)相互作用數(shù)據(jù)庫(kù) DPInteract - DNA-Proteins interactions db五、糖類(lèi)相關(guān)數(shù)據(jù)庫(kù) CarbBank - Complex Carbohydrate Structure Database GlycoSuiteDB - Db of glycan structures TGN -
19、 The Glycoscience Network FCCA - Forum Carbohydrates Coming of Age CARBHYD - Carbohydrate information WWW sites Monosacharide browser - Space filling Fischer projection for monosaccharides六 、蛋白質(zhì)翻譯后修飾相關(guān)數(shù)據(jù)庫(kù) O-GlycBase - O-glycosylated proteins db PhosphoBase - Phosphorylation sites db RESID - Db of Am
20、ino Acid Modifications七、人類(lèi)基因突變及疾病相關(guān)數(shù)據(jù)庫(kù) HMGD - Human Gene Mutation db SVD - Sequence variation db HGBASE - Human Genic Bi-Allelic Sequences db The SNP consortium dbSNP - Human single nucleotide polymorphism (SNP) db List of mutation databases from OMIM List of mutation databases from IMT (Finland) AD
21、B - Albinism db (Mutations in human genes causing albinism) Alpha-glucosidase - Information about human acid alpha-glucosidase (GSD-II) AR mutations - Human androgen receptor mutation db Antithrombin mutation db Asthma and Allergy gene db BIOMDB - Db of mutations causing tetrahydrobiopterin deficien
22、cies BLMbase - Human BLM mutation db (Bloom snydrom) BTKbase - Human BTK mutation db (X-linked agammaglobulinemia) CD40Lbase - Human CD40 ligand mutation db COL1/3 mutation - Human Type I and III collagen mutation db CFTR mutation - Human cystic fibrosis mutation db (CFTR) EMD db - Human Emerin (EMD
23、) mutation db (Emery-Dreifuss muscular dystrophy) KMeyeDB - Eye disease genes db FVII mutation - Human Factor VII mutation db HAMSTeRS - Human Factor VIII mutation db (Haemophilia A) HAeMB - Human Factor IX mutation db (Haemophilia B) FBN1 mutation - Human fibrillin 1 mutation db (Marfan syndrome) G
24、6PD - Human G6PD deficiency resource Galt mutation - Human galactose-1-phosphate uridylyltransferase mutation db (Galactosemia) HEXAdb - Human Hexosaminidase A mutation db (Tay-sachs disease) IL2RGbase - Human IL2RG (Interleukin-2 receptor gamma) mutation db (X-SCID) L1CAM mutation - Human L1CAM mut
25、ation db LDLR mutation - Human LDLR mutation db (Familial hypercholesterolemia) LQTSdb - Long QT syndrome db NCF1base - Human NCF1 mutation db NCF2base - Human NCF2 mutation db Neuromuscular diseases web site NCL - Neuronal Ceroid Lipofuscinoses mutation db OTCase - Human ornithine transcarbamylase
26、(OTCase) website Cytochrome P450 alleles nomenclature p53 mutation db - University of Tokyo p53 mutation db Germline p53 mutation db - University of Prague db of germline p53 mutations PAHdb - Human phenylalanine hydroxylase (PAH) mutation db PAX6 mutation - Human PAX6 mutation db Prion - Prion and
27、prion disease web site RAG1base - Human RAG1 mutation db RAG2base - Human RAG2 mutation db RB1base - Human retinoblastoma-associated protein (RB) mutation db RetNet - Retinal Information Network Retina International Scientific Newsletter - Information on Retinal genes, proteins and diseases TSC - TSC (TSC1/TSC2) variation db TSC2 - Cardiff-Rotterdam Tuberous Sclerosis (TS) db (Tuberin; TSC2) TGDB - Tumor gene db V
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