生物醫(yī)藥與海洋開發(fā)

1、生物醫(yī)藥與海洋開發(fā)1、福建地道藥材澤瀉種質(zhì)復(fù)壯與種苗繁育技術(shù)The Technology of Seed Quality Rejuvenation and Seedling Breeding of Fujian Genuine Medicine Material Alisma orientali種子質(zhì)量是發(fā)展?jié)蔀a的瓶頸, 澤瀉種子壽命短, 常溫下 1年幾乎 喪失發(fā)芽能力, 且種質(zhì)退化嚴(yán)重, 植株生長與藥材質(zhì)量參差不齊產(chǎn)量 低下。經(jīng)種質(zhì)復(fù)壯種子發(fā)芽率不低于 78%、矮縮株不低于 30%、千 粒重不低于 0.22g ; 繁育種苗 38-45天苗高 8-18cm 、 無病斑、 無蟲蛀、 心芽完整、展

2、開真葉保持有 5片以上為合格種苗,實(shí)現(xiàn)穩(wěn)產(chǎn)豐產(chǎn),藥 材質(zhì)量達(dá)到國家藥典標(biāo)準(zhǔn)。The quality of Alisma orientali seed is the key restrictive factor. The seed has a short life-span, almost loses the germinating ability in room temperature in one year. Germplasm degenerates seriously, the plant growes irregularly, and the yield and quality of

3、Alisma orientali is low. With seed quality rejuvenation, the germination percentage is not less than 78%, the dwarfs percentage are not less than 30%,the thousand grain weight is not less than 0.22g. With 38-45 days of breeding, the qualified seedling is with the height of 8-18cm,integrated bud, and

4、 more than 5 true leafs ,without disease and pest speckle. Thus, the yield of Alisma orientali is high and steady, and the quality of Alisma orientali medicinal materials accords with the standard of nation pharmacopoeia.聯(lián)系單位:福建省農(nóng)科院農(nóng)業(yè)生物資源研究所聯(lián)系人:陳菁瑛電話真:0591-875739072、魚腥草病蟲害生態(tài)防治及其標(biāo)準(zhǔn)技術(shù)操作

5、規(guī)程The Ecological Control Measure and SOP of Chinese Herbal Houttuyniae cordata魚腥草是一種具有多種藥用功能的中藥材,以生產(chǎn)注射劑為主, 根莖葉還可作為蔬菜食用, 應(yīng)用廣泛, 但在種植過程容易遭受多種病 蟲為害,造成不同程度損失。生態(tài)防治建立嚴(yán)格防病的種莖基地、杜 絕初侵染源,采用微生物制劑、捕食螨等生態(tài)防治技術(shù)既避免農(nóng)藥、 重金屬污染又可達(dá)到凈化環(huán)境目的,滿足生產(chǎn) GAP 藥材的要求。 The chinese herbal Houttuyniae cordata has many medicinal applicat

6、ions, the main is injection medicine, and it also is used as vegetable. under the condition of man_made protective culture, the yield and quality of Houttuyniae cordata will be lost because of the various pests and diseases. The rhizomatous seed bases of Houttuyniae cordata , which established by Ec

7、ological control measure, will stop the primary insection sources of diseases and pests. Ecological control measure such as microbial preparation and predatory mites will aviod the pesticide and heavy metal pollution, also clean up environment, which satisfies therequirement of medicinal materials G

8、AP.聯(lián)系單位:福建省農(nóng)科院農(nóng)業(yè)生物資源研究所聯(lián)系人:陳菁瑛電話真:0591-875739073、 ISCOMs 技術(shù)在海水魚病害免疫防治中應(yīng)用Using ISCOMs technic to control disease of oceanic fish.獲國家發(fā)明專利的 ISCOMs 制備技術(shù)已用于水產(chǎn)病原菌疫苗和 抗病原的功能性卵黃蛋白制備。若用于海水魚的防治 ,將減少發(fā)病 率 30%以上。The ISCOMs technology has been applied in manufacture of vaccine and functional yelk p

9、rotein. This technology may reduce 30% incidence of seafish disease.聯(lián)系單位:福建省農(nóng)業(yè)科學(xué)院生物技術(shù)研究所聯(lián)系人:龔暉電話真:0591-878454464、復(fù)合酶與膜技術(shù)在木立蘆薈全葉液汁生產(chǎn)中的應(yīng)用示范he Application on The Technology of Complex Enzyme Treatment and Membrane in Production of Aloe Juice本研究率先采用復(fù)合酶處理和膜過濾等技術(shù) , 有效解決木立蘆薈 液汁易沉淀、易褐變的技術(shù)難題,開

10、發(fā)出高穩(wěn)定性、高純度、高有效 成分的木立蘆薈全葉液汁。主要技術(shù)指標(biāo):提取率 >60%;蘆薈甙 (mg/100ml >5; 產(chǎn)品澄清透明, 保質(zhì)期 >12個月; 蛋白質(zhì) (mg/100g : 30-50;可溶性固體物質(zhì)(% :1-3。各項(xiàng)產(chǎn)品指標(biāo)均符合國家相關(guān)標(biāo) 準(zhǔn),實(shí)現(xiàn)年產(chǎn)木立蘆薈全葉液汁 300噸。The study applied the technology of complex enzyme treatment and membrane filtering to solved aloe juice precipitate and browning. Whats mor

11、e, the study exploitated the aole juice of high stability purity and effective component. The main specifications of production is that extraction rate>60%; aloin (mg/100ml >5; the juice transparent , EXP>12 months protein(mg/100g :30-50; soluble solid(% :1-3. All specifications consist wit

12、h related standards of nation. Aloe jiuce produced 300 ton every year.聯(lián)系單位:福建師范大學(xué)生命科學(xué)學(xué)院聯(lián)系人:何文錦傳真:0591-228682105、珍稀貝類西施舌異地育苗產(chǎn)業(yè)化The Nursery Industrialization of Rare Shellfish Xishi Tongue at Lianjiang福建師范大學(xué)擁有 西施舌規(guī)?；斯び缂夹g(shù)科研成果,省 科技廳鑒定達(dá)到國際領(lǐng)先水平。 擬在連江縣異地人工育苗產(chǎn)業(yè)化, 年 增殖種苗 300萬粒,放流海域 200畝,放流增殖將產(chǎn)西施舌商品蚌 1000kg

13、, 年增加產(chǎn)值 800萬元 , 恢復(fù)連江海域西施舌自然資源。Fujian Normal University with the research achievement named"the scale artificial breeding technology of Xishi tongue Coelomactra antiquata " ,will make the technology transfer to put the industrialization of nursery and breeding at Lianjiang. The project aims

14、 to promote the proliferation of 3 million seedlings yearly, discharge waters 200 acres. The proliferation discharge will be 1000 kg of goods and 8 million yuan in output value will be increased. Lianjiang will restore natural resources of the clam.聯(lián)系單位:福建師范大學(xué)聯(lián)系人:高如承電話真:0591-834716706

15、、激光動力鼻咽癌內(nèi)鏡定位儀The diagnosis and localization of NPC with The laser induced fluorescence世界上 80%鼻咽癌發(fā)生在我國南方各省, 鼻咽癌的早期診斷與治 療是提高鼻咽癌患者生存率的關(guān)鍵。 本儀器采用現(xiàn)代光電技術(shù)和高靈敏度探測器件,包括雙波長氬離子激光器、像增強(qiáng)器、高速計(jì)算機(jī)圖 像采集與處理系統(tǒng)、 光纖導(dǎo)光器件與技術(shù)。 通過對腫瘤藥物熒光成像 實(shí)現(xiàn)對早期鼻咽癌的高靈敏度診斷與精確定位。 本項(xiàng)成果可拓展于其 它腫瘤的早期診斷與定位。Nasopharyngeal carcinoma (NPC is a unique m

16、alignant cancer with distinct geographic features from other head and neck epithelial malignancies. There are geographic regions in the world where NPC is endemic, such as in Southeast Asia, or northern Africa, where the annual incidence can be up to 1/4000. A novel optical biopsy system based on th

17、e laser induced fluorescence for the diagnosis and localization of early NPC has been successful developed, which coupled the excitation light into the original white-light transmission system of commercial nasal endoscope and characterized by coaxial imaging for both the fluorescence image and twil

18、ight image from the same targets. The fluorescence and reflection white light from the target tissue surface are alternately imaged by a nasal endoscope, which can be switched in real time for clinical examination of diagnosis and localization of early NPC.聯(lián)系單位:福建師范大學(xué)聯(lián)系人:林宏心電話真:0591-8

19、34653737、結(jié)核病早期特異診斷試劑盒Early specific diagnosis kit for mycobacterium tuberculosis結(jié)核是我國危害最大的傳染病之一, 結(jié)核患者及時(shí)準(zhǔn)確的早期診 斷是結(jié)核規(guī)范性治療的起點(diǎn)。 本項(xiàng)目利用基因工程技術(shù)和細(xì)胞免疫學(xué) 技術(shù)研制出結(jié)核特異性 T 細(xì)胞免疫體外檢測方法 T 細(xì)胞 IFN-體 外釋放試驗(yàn) (IGRA , 對活動性結(jié)核的檢測靈敏度和特異性均在 90%以上。Tuberculosis (TB is one of the most harmful infectious disease in China. The early p

20、athogenic specific diagnosis the precondition for TB control. In this project, a TB specific IFN- release assay was developed. The sensitivity and specificity of the assay for active TB diagnosis were higher than 90%.單位單位:廈門大學(xué)國家傳染病診斷試劑與疫苗工程技術(shù)研究中心 聯(lián)系人:張軍電話真中醫(yī)舌診輔助中成藥使用系統(tǒng)he

21、 Assistant System on the Use of Chinese Patent Drugs by Tongue-inspection of Traditional Chinese Medicine中醫(yī)舌診輔助中成藥使用系統(tǒng)是一套基于中醫(yī)專家經(jīng)驗(yàn)和現(xiàn)代 計(jì)算機(jī)技術(shù)的軟硬件系統(tǒng)。 它能指導(dǎo)中成藥的正確使用, 可廣泛用于藥店、診所、保健中心。The Assistant System on the Use of Chinese Patent Drugs by Tongue-inspection of Traditional Chinese Medicine is a set of sof

22、tware and hardware system based on the experience of traditional Chinese medicine specialist and modern computer technology. It can guide the correct use of Chinese patent drugs, and be applied in the drugstores, clinics and health care centres.單位單位:廈門大學(xué)聯(lián)系人:王彥暉傳真:059221830699、新型生物殺線蟲藥 PL 菌劑的中試與推廣Exp

23、erimentation and Application of biological nematicide " Paecilomyces lilacinu".創(chuàng)制了高殺線蟲活性的 PL 菌劑,每克粉劑活孢子 5×108以上, 每克原粉 1010以上,比國外高 5倍;線蟲減少 80%以上,促生增產(chǎn) 15%以上; 解決了貨架壽命難題; 原料低廉, 取得 2 項(xiàng)發(fā)明專利授權(quán); 已應(yīng)用在大豆、番茄等,同時(shí)可抑制柑橘黃化,示范 2萬棵。無三廢 排放無毒無害無污染; 成為禁用化學(xué)殺線蟲藥的替代產(chǎn)品, 已列入國 家星火計(jì)劃項(xiàng)目。PL preparation had excell

24、ent nematocidal effect was be created. Its content higher 5 times than overseas, preponderated over 5×108live spores/gram powder preparation, and >1010live spores/gram original powder. Nematodes decreased >80%, yield increase >15%, and shelf life difficut problem has been resolved. Raw

25、 material price is cheap and 2 invention patent warrant had been obtained.It has been applied for great area in citrus, tomato and soybean, andhas being demonstrated for 20 thousands of citrus trees. It have not any toxi, harm and pollute. Therefore become substitute of forbited chemical nematocides

26、 , and ranked on National Star and Torch Program of China. 單位單位:廈門大學(xué)聯(lián)系人:潘滄桑電話真:0592-218062410、海洋生物毒素標(biāo)樣研制及其檢測新技術(shù)Mass production of paralytic shellfish toxins and novel detection methods本項(xiàng)目將分離純化中國沿海典型麻痹性貝毒 C1/C2, GTX1/4, GTX2/3和 GTX5,運(yùn)用液相色譜 -質(zhì)譜聯(lián)用技術(shù)和核磁共振等方法定 量毒素純度和含量, 制備高純度毒素標(biāo)樣, 建立麻痹性貝毒的大

27、規(guī)模 生物生產(chǎn)技術(shù); 合成篩選適宜的毒素化學(xué)傳感器 冠狀醚, 優(yōu)化毒素 和冠狀醚的反應(yīng)體系, 結(jié)合多重時(shí)間分辨熒光技術(shù), 建立麻痹性貝毒 多重時(shí)間分辨熒光檢測技術(shù),并用于水產(chǎn)品中麻痹性貝毒的檢測。 This project will mass produce high purity paralytic shellfish toxins (PSTs using a combination of photobioreactor, HPLC-MS and NMR approaches, and develop novel PSTs detection method based on fluoresc

28、ent characteristics of crown ethers, and finally apply this product and method for PSTs monitoring in seafoods.單位單位:廈門大學(xué)聯(lián)系人:王大志電話真:0592-218065511、富集硒酵母生產(chǎn)Production of Concentrating Selenium Ions of Yeast缺硒容易產(chǎn)生機(jī)體抗病能力下降、肝炎、糖尿病、癌癥等多種疾 病。 北京大學(xué)的科研人員修飾了微生物的基因獲得優(yōu)勢菌株, 在微生 物發(fā)育中將硒元素與其蛋白質(zhì)結(jié)合, 形成與人

29、體自身結(jié)構(gòu)類似的生物 態(tài)硒產(chǎn)品,具有毒性低,吸收快等優(yōu)點(diǎn),達(dá)到國際先進(jìn)水平,可取代 無機(jī)硒及人工合成的有機(jī)化合物等低端產(chǎn)品。Creatures are easy to get sickness if they lack selenium.Researchers obtained advantage strains by modified microbial genes . By used the strains, selenium element can combined with proteins to get the selenium-enriched biological product

30、. It has low toxicity and is easy to absorption by creatures. It may replace these low quality Se produces, for example inorganic selenium or synthetic organic selenium compounde. This technology is appraised to have reached international advanced level.單位單位:北京大學(xué)聯(lián)系人:羅大珍電話真/p>

31、12、用于慢?；蛟\斷的納米基因傳感器的研制Development of nano-genic biosensors of Chronic Myelocytic Leukemia DNA本項(xiàng)目相關(guān)研究是在國家 863計(jì)劃, 國家自然科學(xué)基金, 福建省 重大項(xiàng)目及福建省產(chǎn)業(yè)技術(shù)開發(fā)項(xiàng)目的資助下進(jìn)行的。 本項(xiàng)目將具有 靈敏、簡便、準(zhǔn)確、經(jīng)濟(jì)等優(yōu)點(diǎn) DNA 電化學(xué)生物傳感器用于慢粒白 血病(CML 的早期診斷。結(jié)合分子雜交技術(shù)、納米技術(shù)、電化學(xué) 檢測技術(shù),通過 CML 相關(guān)基因的分子自組裝等固定化技術(shù)研究、高 靈敏度雜交指示劑的篩選及其與 DNA 的作用機(jī)理等研究,建立高靈 敏度、 高特異性、 簡便

32、經(jīng)濟(jì)的 CML 基因檢測新方法, 成功研制了 CML 的早期診斷的電化學(xué)傳感器樣機(jī), 有望推廣應(yīng)用于其他類型白血病及 腫瘤的早期診斷和篩選抗腫瘤新藥等生命科學(xué)領(lǐng)域, 將對腫瘤等疾病 診斷領(lǐng)域產(chǎn)生巨大的經(jīng)濟(jì)社會效益。Fujian Medical University was founded in 1937. Through the development of the past 70 years, the school has established talents training system to cultivante bachelors, masters and doctors and

33、formed the fine school spirit which was “ diligence, preciseness, practicality, innovation ” to become an integrated provincial Medical University which straddles several disciplines: teaching, scientific research, medical treatment, prevention and social services. In 2003, the school was graded as

34、one of key building universities by the Fujian Provincial People'sGovernment.單位單位:福建醫(yī)科大學(xué)聯(lián)系人:張艷玲電話真:0591-2286205413、型中藥脫毛、脫皮暨除塵裝置a new type equipment for depilating and sheding of some Chinese herbs, and also companing with ash handling因部分中藥材如澤瀉、 莪術(shù)等球莖表面帶有粗皮或粗毛, 無法直 接使用,需經(jīng)多道煩瑣、耗能、耗

35、時(shí)的加工。本成果采用變速電機(jī)帶 動內(nèi)面粗糙的圓形滾筒對此類藥材進(jìn)行加工, 達(dá)到脫毛、 脫皮的目的; 同時(shí),附屬的除塵機(jī)構(gòu)可以有效地實(shí)施除塵,防止污染環(huán)境。是一種 高效、環(huán)保、節(jié)能新裝置。Some Chinese herbal medicines have rough surface with coarse wool such as Zexie, Ezhu bulbs, which could not be directly used for medicine. They need several processing steps with cumbersome, energy, time-co

36、nsuming. This achievement introduce the variable speed motor-driven to carry the circular drum with rough internal surface to reach sheding, peeling purpose; At the same time, the subsidiary dust removal attachment can be effectively implemented to prevent pollution of the environment. This achievem

37、ent is a highly efficient, environmentalfriendly, energy-saving new device.聯(lián)系單位:福建中醫(yī)學(xué)院聯(lián)系人:吳水生傳真:0591-2286113514、硫酸阿貝卡星注射液Injection of Arbecacine Sulfate產(chǎn)品的主要用途:應(yīng)用于因敏感菌所致的支氣管炎、肺炎、腎盂 腎炎、腹膜炎、膀胱炎、中耳炎、敗血癥等疾病人群。本產(chǎn)品對革蘭陽性和陰性桿菌,如沙雷桿菌、大腸桿菌、變形桿菌、 枸櫞酸桿菌、腸桿菌屬、克雷白桿菌等良好的抗菌活性;對氨基糖苷 類滅活霉有高度拮抗力,對金黃色葡萄球菌(包括耐甲氧西林菌株 有良好

38、的抗菌作用, MIC50或 MIC80為 0.78-1.56ug/耐,在氨基糖苷 類抗生素中最強(qiáng)。Arbecacine sulfate is a semisynthetic antibiotic having a high antibacterial activity against drugresistant bacteria and hence it is widely used in clinical applications.聯(lián)系單位:福州博立醫(yī)藥科技有限公司聯(lián)系人:張國慶傳真:0591-8807380715、應(yīng)用多酶體技術(shù)提高蜂花粉中活性蛋白提取率的中試研究 The pilot pl

39、ant research for increasing the refining rate of active albumen in honeybee pollen by adopting enzyme technology該項(xiàng)目是應(yīng)用酶工程原理,采用以纖維素酶為主體的多酶體系, 根據(jù)蜂花粉細(xì)胞特征, 設(shè)定細(xì)胞壁酶解催化過程, 使細(xì)胞壁溶解破裂, 整個酶解條件溫和,可最大程度釋放花粉中活性蛋白和其它營養(yǎng)成 分。該項(xiàng)目工藝簡單、節(jié)能環(huán)保,已進(jìn)行了中試研究,總結(jié)出了規(guī)范 的工藝規(guī)程,可投入工業(yè)化生產(chǎn)。This project ,applying enzyme engineering princip

40、le and adopting the cellulose-centered multienzyme system ,according to bee pollen cell characteristic , set a course for cellular wall enzyme to decompose and make cellular wall dissolved. The whole dissolution is gentle.It also can release the active albumen and nutrition ingredient in pollen in t

41、he maximum extent. The technics of this project is simple,Energy-saving and environmental protection,and accomplishing the pilot plant research;We have summarized a normative technic regulation for it plunging into industrial producing.聯(lián)系單位:福州恒豐量子生物科技有限公司聯(lián)系人:羅小梅電話真:0591-8399769116、白血病

42、殘留病灶 ALLGLO 探針熒光定量 PCR 診斷試劑盒研發(fā) 與生產(chǎn)To Explore and Produce AllGlo Real-time Quantitative PCR for Diagnosing Minmal Residual Disease in Patients with Leukemia 此成果是一種具有中國人自主知識產(chǎn)權(quán)的生物高科技產(chǎn)品, 具有 高敏感性、高特異性和高檢出率,達(dá)到國際先進(jìn)水平?？捎行У赜糜?白血病微小殘留病基因的檢測, 協(xié)助判斷白血病的臨床診治效果和預(yù) 后判斷。 該檢測試劑盒的產(chǎn)業(yè)化具有廣闊的市場前景, 能提高福建基 因診斷試劑企業(yè)在全國的影響,促進(jìn)我國

43、今基因診斷市場的快速發(fā) 展。This achievement is a kind of high-tech biological products , which has independent intellectual property rights . It also has more higher sensitivity 、 specificity and detection rate than others , and reaches advanced international standards. It can effectively be used to diagnose min

44、imal residual diseases of leukemia genes, and to determine the effectiveness of clinical diagnosis and treatment and the prognosis of leukemia patients. Its industrialization has a vast market prospect, and it can improve the influence of genetic diagnostic reagent of Fujian enterprises in our count

45、ry and rapidly promote the development of gene diagnosis.聯(lián)系單位:福建醫(yī)科大學(xué)聯(lián)系人:沈建箴傳真:0591-2805370017、 “ 海保明 ” 明目功能性食品The Functional Food for Improving Eyesight本項(xiàng)目從石決明中提取有效成分 , 配合中醫(yī)傳統(tǒng)驗(yàn)方 , 研制成有明 目等功能的海洋功能性食品, 對改善用眼過度的現(xiàn)代人的視力狀況大 有裨益。 本項(xiàng)目采用了多項(xiàng)先進(jìn)技術(shù)以確保其工藝的先進(jìn)性及制成品 的質(zhì)量。 其中石決明水解利用技術(shù)已獲得國家知識產(chǎn)權(quán)局的發(fā)明專利 申請?zhí)枴?產(chǎn)品適合各種年齡人群的視力

46、保健, 可發(fā)揮石決明清肝明目 的作用,改善眼部炎癥、弱視、白內(nèi)障和近視等眼病的治療效果。 This program is contributed to improving the over-exhausted eyesight of modern people by extracting ingredients from the abalone shells to develop a functional ocean food in accordance with the recipes of traditional Chinese medicine proved effective. Som

47、e Advanced techniques had been adopted to ensure quality of the product. A patent in hydrolysis technology of the abalone shells has been awarded by the state Intellectual Property Office. The product functions well, to people at various ages, as being used to protect liver, to improve eyesight and

48、to alleviate such eye diseases as inflammation, inferior eyesight, cataract and shortsightedness.聯(lián)系單位:廈門集美大學(xué)聯(lián) 系 人:邱澄宇電話真:0592-618126318、大腸菌群和大腸桿菌檢測新產(chǎn)品開發(fā)Development of new productions to detect coliform and Escherichia coli大腸菌群和大腸桿菌是食品、 藥品、 環(huán)境檢測的重要衛(wèi)生學(xué)指標(biāo)。 本項(xiàng)目于 2002年獲得國家 863計(jì)劃立項(xiàng),經(jīng)過 2年研究,開

49、發(fā)出能 準(zhǔn)確檢測大腸桿菌和大腸菌群的培養(yǎng)基, 快速、 定量檢測技術(shù)以及簡 便、 實(shí)用的檢測試紙產(chǎn)品。 已經(jīng)申請兩項(xiàng)國家發(fā)明專利, 一篇研究論 文獲中國海洋學(xué)會 2003年學(xué)術(shù)年會優(yōu)秀論文獎。這些成果適用于食 品、 藥品、 餐具以及環(huán)境樣品中的大腸桿菌和大腸菌群檢測, 經(jīng)過定 型、轉(zhuǎn)化后能夠形成具有市場競爭優(yōu)勢的產(chǎn)品。The hygienic indexes of Coliform and Escherichia coli are indispensable in the routine detection of food, drug and environmental samples. Thi

50、s program was supported by Chinas Hi-tech Research and Development Program(863 program in 2002. After a two-year research, productions (including differential culture media for coliform and Escherichia coli, rapid and quantitative detection technology, convenient and practicality detection test pape

51、r had been acquired. Two patents hasbeen applied and a research paper was awarded excellence paper at the annual academic meeting of China Oceanography Academy in 2003. These productions are applicable to detect coliform and Escherichia coli in food、 drug 、 dishware and environmental samples. And it

52、 is advisable to put them into manufacture for their advantages in market competition. 聯(lián)系單位:廈門集美大學(xué)聯(lián)系人:王志勇電 話:(0592 6180464傳 真:(0592 618126319、大黃魚全雌化育苗技術(shù)Breeding genetically improved all female fries of large yellow croaker 大黃魚雌魚生長速度遠(yuǎn)快于雄魚,本項(xiàng)目綜合應(yīng)用了選擇育種、 雜交育種、染色體組操作、 分子標(biāo)記輔助選擇以及人工轉(zhuǎn)性技術(shù),將 遺傳改良和性別控制有機(jī)地結(jié)合,培

53、育遺傳性雌化優(yōu)質(zhì)良種大黃魚 苗。由本技術(shù)培育的大黃魚苗雌性率達(dá) 96.7100%,養(yǎng)殖成活率顯 著提高,產(chǎn)量提高 30%以上。The growth speed of female large yellow croaker is much higher than that of the male ones. In our study, the techniques including selection breeding 、 cross breeding、 chromosomal manipulation、 molecular marker assisted selection and arti

54、ficial sex reversal, which integrates genetic improvement and sex determination, were used to breed geneticallyimproved female fries of large yellow croaker. The results showed that the female fries ratio is 96.7%100%and the survival ratio improved obviously and the production increased 30%.聯(lián)系單位:廈門集

55、美大學(xué)聯(lián)系人:王志勇電話真:0592-618147620、 谷氨酰胺轉(zhuǎn)胺酶的發(fā)酵生產(chǎn)及應(yīng)用如果建立一個擁有 3個 30噸級發(fā)酵罐的中型發(fā)酵工廠,采用本 項(xiàng)目技術(shù)進(jìn)行 TGase 的發(fā)酵法生產(chǎn), 其經(jīng)濟(jì)效益測算 (詳略 結(jié)果如 下:年產(chǎn)酶量(粗酶 1801116萬酶活單位;年產(chǎn)值 5400萬元;年 生產(chǎn)、 出廠銷售等總成本 874.4萬元; 年收益 4525.6萬元。 合作方式:尋求水產(chǎn)品或肉類食品添加劑生產(chǎn)或營銷企業(yè), 合作開發(fā), 進(jìn)一步提 高 TGase 的產(chǎn)量, 研制酶活穩(wěn)定性高、 適用于水產(chǎn)品和肉類加工生產(chǎn) 應(yīng)用的 TGase 商品劑型, 開拓 TGase 的

56、應(yīng)用與銷售市場, 促進(jìn) TGase 的產(chǎn)業(yè)化生產(chǎn)與廣泛應(yīng)用。Based on our market analysis, we estimate if a fermentation factory with three 30m3 vessels is built, 18 billion U crude TGase which worth $54million can be produced annually by this techniques. The cost for producing and selling it is only $1.05million and the annual p

57、rofit is as high as $5.45million.Format of cooperation :We are looking for companies that are producing or trading of aquatic and meat additives. With collaboration, our goal is to increase the production of TGase and to generate TGase with higher activity and thermal stability to meet the commercia

58、l requirement of TGase in aquatic and meat processing. Also with collaboration, we are able to promote and open up the market of application and trading of TGase.聯(lián)系單位:廈門集美大學(xué)聯(lián)系人:蔡慧農(nóng)電 話 真:0592-618126321、海蠣殼綜合利用技術(shù)Integrated Utilization of Oyster Shell福建省牡蠣殼擁有量全國第一, 而牡蠣殼的開發(fā)因高能耗、 高污 染 “ 瓶頸

59、” 難題而處于停滯狀態(tài)。本項(xiàng)目在研究牡蠣鈣的生物活性、毒 理試驗(yàn)基礎(chǔ)上, 研究牡蠣殼在較溫和條件下經(jīng)無害處理, 提制生物鈣 和無機(jī)鹽的資源化利用技術(shù)。該技術(shù)具有低能耗,污染小、產(chǎn)率高的 特點(diǎn)。The output of Oyster Shell in Fujian Province is highest in whole China, whereas the utilization of Oyster Shell stagnates because such “bottleneck” as high energy consumption and serious pollution. Based on the