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1、抗菌藥物分類及規(guī)定日劑量(DDD)2011年8月 衛(wèi)生部抗菌藥物臨床應(yīng)用監(jiān)測網(wǎng) ATC code English_name 藥品名稱 DDD值(WHO+C) DDD值(WHO-ATC)Amoxicillin andFlucloxacillin阿莫西林氟氯西林5.005.00Amoxicillin andFlucloxacillin阿莫西林氟氯西林1.501.50Amoxicillin andDicloxacillin阿莫西林雙氯西林2.002.00Apalcillin阿帕西林2.002.00Astromicin阿司米星1.501.50Ampicillin andProbenecid氨芐西林丙磺

2、舒4.504.50Ampicillin andCloxacillin氨芐西林氯唑西林3.003.00Faropenem法羅培南0.500.50furbenicillin呋布西林6.006.00Guamecycline胍甲環(huán)素1.201.20ErythromycinCyclocarbonate環(huán)酯紅霉素1.251.25J01MA15Gemifloxacin吉米沙星0.320.32Leucomycin吉他霉素0.800.80Leucomycin吉他霉素1.201.20Fosfomycin andTrimethoprim磷霉素鈣甲氧芐啶0.450.45lenampicillin侖氨西林1.751.7

3、5J01MA07Lomefloxacin洛美沙星0.400.40J01MA07Lomefloxacin洛美沙星0.400.40Mekeumycin麥白霉素1.001.00Mezlocillin andSulbactam美洛西林舒巴坦6.006.00Nafcillin奈夫西林4.004.00Nafcillin奈夫西林3.503.50J01MA06Norfloxacin諾氟沙星0.400.40J01GB03Gentamicin慶大霉素0.300.30Norvancomycin去甲萬古霉素1.601.60P01AB07Secnidazole塞克硝唑2.002.00Cefalexin andTrime

4、thoprim頭孢氨芐甲氧芐啶0.900.90Cefcidin頭孢克定4.004.00Cefathiamidine頭孢硫脒3.003.00Cefpimizolec頭孢咪唑J01DD62Cefoperazone,combinations頭孢哌酮鈉舒巴坦4.004.00J01DD62Cefoperazone,combinations頭孢哌酮他唑巴坦4.004.00Cefadroxil andTrimethoprim頭孢羥氨芐甲氧芐啶0.900.90J01DD54Ceftriaxone,combinations 頭孢曲松鈉舒巴坦2.002.00Cefoselis頭孢噻利2.002.00Cefotax

5、ime and Sulbactam頭孢噻肟舒巴坦4.004.00J01DB11Cefroxadine頭孢沙定0.750.75Ceftazidime andSulbactam頭孢他啶舒巴坦4.004.00Cefteram頭孢特侖酯0.380.38J01DB10Cefacetrile頭孢乙氰4.004.00Cefazolin and Sulbactam頭孢唑啉舒巴坦3.003.00Cefuzonam頭孢唑喃1.501.50Tosufloxacin妥舒沙星0.380.38S01AA22Micronomicin小諾米星0.180.18J01MA04Enoxacin依諾沙星0.400.40Etimici

6、n依替米星0.250.25Erythromycin Estolate依托紅霉素1.381.38Acetylspiramycin乙酰麥迪霉素0.900.90J01ED20CombinationsSulfadiazine增效聯(lián)磺1.921.92J01GB09Dibekacin地貝卡星0.140.14gJ01XB02Polymyxin B多粘菌素B0.150.15gJ01AA02Doxycycline多西環(huán)素0.100.1gJ01AA02Doxycycline多西環(huán)素0.100.1gG01AF02Clotrimazole克霉唑0.100.1gG01AF04Miconazole咪康唑0.100.1gJ

7、01AA12Tigecycline替加環(huán)素0.100.1gG01AF05Econazole益康唑0.100.1gG01AA01Nystatin制霉菌素0.100.1MUJ01GB03Gentamicin慶大霉素0.240.24gJ01GB01Tobramycin妥布霉素0.240.24gJ01GB08Sisomicin西索米星0.240.24gD01BA02Terbinafine特比奈芬0.250.25gJ02AC01Fluconazole氟康唑0.200.2gJ02AC01Fluconazole氟康唑0.200.2gJ01MA10Rufloxacin蘆氟沙星0.200.2gJ01AA08Mi

8、nocycline米諾環(huán)素0.200.2gJ01AA08Minocycline米諾環(huán)素0.200.2gJ01MA13Trovafloxacin曲伐沙星0.200.2gJ01MA13Trovafloxacin曲伐沙星0.200.2gJ01MA09Sparfloxacin司帕沙星0.200.2gJ02AB02Ketoconazole酮康唑0.200.2gJ02AC02Itraconazole伊曲康唑0.200.2gJ02AC02Itraconazole伊曲康唑0.200.2gJ01GB07Netilmicin奈替米星0.350.35gJ01GB07Netilmicin奈替米星0.350.35gJ0

9、1FA10Azithromycin阿奇霉素0.300.3gJ01FA06Roxithromycin羅紅霉素0.300.3gG01AF08Ttioconazole噻康唑0.300.3gJ02AC03Voriconazole伏立康唑0.400.4gJ02AC03Voriconazole伏立康唑0.400.4gJ01MA08fleroxocin氟羅沙星0.400.4gJ01MA08fleroxocin氟羅沙星0.400.4gJ01MA11Grepafloxacin格帕沙星0.400.4gJ01MA16Gatifloxacin加替沙星0.400.4gJ01MA16Gatifloxacin加替沙星0.4

10、00.4gJ01EA01Trimethoprim甲氧芐氨嘧啶0.400.4gJ01EA01Trimethoprim甲氧芐氨嘧啶(TMP)0.400.4gJ01MA14Moxifloxacin莫昔沙星0.400.4gJ01MA14Moxifloxacin莫昔沙星0.400.4gJ01XA02Teicoplanin替考拉寧0.400.4gG01AF11Ketoconazole酮康唑0.400.4gJ01DD13Cefpodoxime頭孢泊肟0.400.4gJ01DD14Ceftibuten頭孢布烯(布坦)0.400.4gJ01DD08Cefixime頭孢克肟0.400.4gJ01MA01Oflox

11、acin氧氟沙星0.400.4gJ01MA01Ofloxacin氧氟沙星0.400.4gJ01GB11Isepamicin異帕米星0.400.4gJ01FA10Azithromycin阿奇霉素0.500.5gJ01FA13Dirthromycin地紅霉素0.500.5gJ01MA02Ciprofloxacin環(huán)丙沙星0.500.5gD01BA01Griseofulvin灰黃霉素0.500.5gG01AF01Metronidazole甲硝唑0.500.5gJ01FA09Clarithromycin克拉霉素0.500.5gJ01DC02Cafuroxime頭孢呋辛酯0.500.5gJ01MA12L

12、evofloxacin左氧氟沙星0.500.5gJ01MA12Levofloxacin左氧氟沙星0.500.5gJ01EC02Sulfadiazine磺胺嘧啶0.600.6gJ04AB03Rifamycin利福霉素0.600.6gJ01AA05Metacycline美他環(huán)素0.600.6gJ01CA08Pivmecillinam匹美西林0.600.6gJ01CE09Procainebenzylpenicillin普魯卡因青霉素0.600.6gJ01DD15Cefdinir頭孢地尼0.600.6gJ01MB04Pipemidic acid吡哌酸0.800.8gJ01FA12Rokitamycin

13、羅他霉素0.800.8gJ01MA06Norfloxacin諾氟沙星0.800.8gJ01MA03Pefloxacin培氟沙星0.800.8gJ01MA03Pefloxacin培氟沙星0.800.8gJ01FA15Telithromycin泰利霉素0.800.8gJ01MA04Enoxacin依諾沙星0.800.8gJ01GB06Amikacin阿米卡星1.001.0gJ01CA04Amoxicillin阿莫西林1.001.0gJ01CA04Amoxicillin阿莫西林1.001.0gJ01CR02Amoxiciliin andClavulanate Pot阿莫西林克拉維酸鉀1.001.0g

14、J01CR02Amoxiciliin andSulbactam阿莫西林鈉舒巴坦1.001.0gJ01XD03Ornidazole奧硝唑1.001.0gJ01DH03Ertpenem厄他培南1.001.0gJ01BG10Ribostamycin核糖霉素1.001.0gJ01FA01Erythromycin紅霉素1.001.0gJ01FA01Erythromycin紅霉素1.001.0gJ01MA02Ciprofloxacin環(huán)丙沙星1.001.0gJ01GB04Kanamycin卡那霉素1.001.0gJ01FA09Clarithromycin克拉霉素1.001.0gJ01GA01Strepto

15、mycin鏈霉素1.001.0gJ01FA03Midecamycin麥迪霉素1.001.0gJ02AB01Miconazole咪康唑1.001.0gJ01MA18Pazufloxacin帕珠沙星1.001.0gJ01CG01Sulbactan舒巴坦鈉1.001.0gJ01AA07Tatracycline四環(huán)素1.001.0gJ01AA07Tatracycline四環(huán)素1.001.0gJ01DC10Cefprozil頭孢丙烯1.001.0gJ01DC04Cefaclor頭孢克洛1.001.0gJ01DC06Cefonicide頭孢尼西1.001.0gJ01DD10Cefetamet頭孢他美酯1.

16、001.0gJ01AA06Oxytetracycline土霉素1.001.0gJ01AA06Oxytetracycline土霉素1.001.0gJ01GB05Neomycin新霉素1.001.0gJ01FA05Oleandomycin竹桃霉素1.001.0gJ01DH05Biapenem比阿培南1.201.2gJ01FF01Clindamycin克林霉素1.201.2gJ01XX08Linezolid利奈唑胺1.201.2gJ01XX08Linezolid利奈唑胺1.201.2gJ01CA11Mecillinan美西林鈉1.201.2gJ01CR01Ampicillin and Sulbact

17、am氨芐西林舒巴坦1.501.5gP01AB03Ornidazole奧硝唑1.501.5gJ01XC01Fusidic acid夫西地酸1.501.5gJ01XC01Fusidic acid夫西地酸1.501.5gJ01BA02Thiamphenicol甲砜霉素1.501.5gJ01BA02Thiamphenicol甲砜霉素1.501.5gJ01XD01Metronidazole甲硝唑1.501.5gJ01CR04sultamicillin舒他西林1.501.5gJ01XD02Tinidazole替硝唑1.501.5gA07AA02Nystatin制霉菌素1.501.5MUJ01FF01Cli

18、ndamycin克林霉素1.801.8gJ01FF02Lincomycin林可霉素1.801.8gJ01FF02Lincomycin林可霉素1.801.8gJ02AX01Flucytosine氟胞嘧啶10.0010.0gJ02AX01Flucytosine氟胞嘧啶10.0010.0gJ01CA09Azlocillin阿洛西林12.0012.0gJ01CA03Carbenicillin羧芐西林12.0012.0gJ01CA12Piperacilin哌拉西林14.0014.0gJ01CR05Piperacillin andsulbactam哌拉西林鈉舒巴坦14.0014.0gJ01CR05Pipe

19、racilin andTazobactam哌拉西林鈉他唑巴坦14.0014.0gJ01CA16Sulbenicillin磺芐西林15.0015.0gJ01CA13Ticarcillin替卡西林15.0015.0gJ01CR03Ticarcillin andClavulanate Pot替卡西林克拉維酸鉀15.0015.0gJ01CA01Ampicillin氨芐西林2.002.0gJ01CA01Ampicillin氨芐西林2.002.0gJ01CR01Ampicillin and Sulbactam氨芐西林舒巴坦2.002.0gJ01CF04Oxacillin苯唑西林2.002.0gJ01CF0

20、4Oxacillin苯唑西林2.002.0gJ01CF05Flucloxacillin氟氯西林2.002.0gJ01CF05Flucloxacillin氟氯西林2.002.0gJ01DC14Flomoxef氟氧頭孢2.002.0gJ01FA01Erythromycinethylsuccinate琥乙紅霉素2.002.0gJ01EC01Sulfamethoxazole磺胺甲噁唑2.002.0gP01AB01Metronidazole甲硝唑2.002.0gJ01FA07Josamycin交沙霉素2.002.0gJ01CF02cloxacillin氯唑西林2.002.0gJ01CF02cloxaci

21、llin氯唑西林2.002.0gJ01DH02Meropenem美羅培南2.002.0gJ01DH55Panipenem and Betamipron帕尼培南2.002.0gJ01CE02Phenoxymethylpenicillin青霉素2.002.0gJ01CF01dicloxacillin雙氯西林2.002.0gJ01CF01dicloxacillin雙氯西林2.002.0gP01AB02Tinidazole替硝唑2.002.0gJ01DB01Cefalexin頭孢氨芐2.002.0gJ01DE01Cefepime頭孢吡肟2.002.0gJ01DD09Cefodizime頭孢地秦2.00

22、2.0gJ01DD05Cefmenoxime頭孢甲肟2.002.0gJ01DB09Cefradine頭孢拉定2.002.0gJ01DB09Cefradine頭孢拉定2.002.0gJ01DC13Cefbuperazone頭孢拉宗2.002.0gJ01DD11Cefpiramide頭孢匹胺2.002.0gJ01DB05Cefadroxil頭孢羥氨芐2.002.0gJ01DD04Ceftriaxone頭孢曲松2.002.0gJ01XA01Vancomycin萬古霉素(穩(wěn)可信)2.002.0gJ01DH51Imipenem and Cilastatin亞胺培南/西司他丁2.002.0gJ01CR02

23、Amoxiciliin andClavulanate Pot阿莫西林克拉維酸鉀3.003.0gJ01CR02Amoxicillin andSulbactam阿莫西林鈉舒巴坦3.003.0gA07AA06Paromomycin巴龍霉素3.003.0gJ01XX04Spectinomycin大觀霉素3.003.0gJ01BA01Chloramphenicol氯霉素3.003.0gJ01BA01Chloramphenicol氯霉素3.003.0gJ01DC02Cafuroxime頭孢呋辛3.003.0gJ01DB02Cefaloridine頭孢噻啶3.003.0gJ01DB04Cefazolin頭孢

24、唑林3.003.0gJ01FA02Spiramycin乙酰螺旋霉素3.003.0gJ01XB01Colistin粘菌素(多粘菌素E)3.003.0MUJ01CE08Benzathinebenzylpenicillin芐星青霉素3.603.6gJ01CE01Benzylpenicillin青霉素3.603.6gJ02AA01Amphotericin B兩性霉素35.0035mgJ02AA01Amphotericin B兩性霉素脂質(zhì)體35.0035mgJ01CA19Aspoxicillin阿撲西林4.004.0gJ01DF01Aztreonam氨曲南4.004.0gJ01EB03Sulfadimi

25、dine磺胺二甲嘧啶4.004.0gJ01EC02Sulfadiazine磺胺嘧啶4.004.0gJ01DD06Latamoxef拉氧頭孢4.004.0gJ01DD03Cefsilodin頭孢磺啶(頭孢磺吡芐)4.004.0gJ01DC11Ceforanide頭孢雷特4.004.0gJ01DC09Cefmetazole頭孢美唑4.004.0gJ01DC12Cefminox頭孢米諾4.004.0gJ01DD12Cefoperazone頭孢哌酮4.004.0gJ01DB08Cefapirin頭孢匹林4.004.0gJ01DE02Cefpirome頭孢匹羅4.004.0gJ01DB03Cefalot

26、in頭孢噻吩4.004.0gJ01DD01Cefotaxime頭孢噻肟4.004.0gJ01DD02Ceftazidime頭孢他啶4.004.0gJ01DC07Cefotiam頭孢替安4.004.0gJ01DD07Ceftizoxime頭孢唑肟4.004.0gJ02AX05Caspofungin卡泊芬凈50.0050mgJ01CA10Mezlocillin美洛西林6.006.0gJ01DC03Cefamandole頭孢孟多(頭孢羥唑)6.006.0gJ01DB12Ceftezole頭孢替唑6.006.0gJ01DC01Cefoxitin頭孢西丁6.006.0gG01AA04Candicidin

27、克念菌素6.006mgJ01XX01Fosfomycin磷霉素8.008.0g DDD值 (C)給藥途徑 備注5.0gP(1:1)1.5gO(1:1)2.0gO(2:1)2.0gP1.5gP4.5gP3.0gP(1:1)0.5gO6.0gP1.2gO1.25gO0.32gO0.8gP1.2gO0.45gO(5:1)1.75gO0.4gP0.4gO1.0gO6.0gP*4.0gP3.5gO0.4gP0.3gO1.6gP2.0gO0.9gO(5:1)4.0gP3.0gP未查到4.0gP*4.0gP0.9gO(5:1)2.0gP*2.0gP4.0gP*0.75gO4.0gP*0.375gO4.0gP

28、3.0gP*1.5gP0.375gO0.18gP0.4gP0.25gP1.375gO0.9gO(5:1)1.92gO(4片)PPPOVVPVVPPPOPOOPOPOOOPOPOOOVPOPOOPOPOPOPVOOOPOPPOPOVOOPOOPOOPOOOOPOOOPPOO*O*PPPPOOPPPOPPPPOOOPOPOOPPOPOPOOPOPOPO*POPPOPOPPPP*P*PPP*POPPOPOPOOOOPOPP*OPOOOPPPPOPPOPPP*P*P*OPPOPPPOPPPPPPPPPPPPPPPPPPPPPPPPPPPVP說明書 1.給藥途徑中:O(oral).口服給藥;P(pare

29、nteral).腸道外給藥(注射給藥);V(vaginal).陰道給藥。 2.本表藥品排序是按照“ATC code”(即ATC編碼),沒有“ATC code”的藥品集中排在后面,以英文名排序。 3.表中“DDD(C)”值,監(jiān)測網(wǎng)按WHOATC制定DDD的原則,經(jīng)過專家討論制定的DDD,僅供監(jiān)測網(wǎng)范圍內(nèi)統(tǒng)計使用。 4.根據(jù)WHOATC統(tǒng)計藥物DDD數(shù)的原則和方法,凡-內(nèi)酰胺類藥物(青霉素類、頭孢菌素類)與酶抑制劑的組合制劑,在計算其DDD數(shù)時,只 考慮主要藥物的含量,不統(tǒng)計酶抑制劑的量。說明書 1.給藥途徑中:O(oral).口服給藥;P(parenteral).腸道外給藥(注射給藥);V(va

30、ginal).陰道給藥。 2.本表藥品排序是按照“ATC code”(即ATC編碼),沒有“ATC code”的藥品集中排在后面,以英文名排序。 3.表中“DDD(C)”值,監(jiān)測網(wǎng)按WHOATC制定DDD的原則,經(jīng)過專家討論制定的DDD,僅供監(jiān)測網(wǎng)范圍內(nèi)統(tǒng)計使用。 4.根據(jù)WHOATC統(tǒng)計藥物DDD數(shù)的原則和方法,凡-內(nèi)酰胺類藥物(青霉素類、頭孢菌素類)與酶抑制劑的組合制劑,在計算其DDD數(shù)時,只 考慮主要藥物的含量,不統(tǒng)計酶抑制劑的量。WHOATC抗菌藥物分類表J ANTIINFECTIVES FOR SYSTEMIC USEJ01 ANTIBACTERIALS FOR SYSTEMICUS

31、EJ01A TETRACYCLINES四環(huán)素類抗生素J01AA Tetracyclines四環(huán)素類藥物J01B AMPHENICOLS氯霉素類J01BA Amphenicols氯霉素類J01C BETA-LACTAM ANTIBACTERIALS,PENICILLIN -內(nèi)酰胺抗菌素,青霉素J01CA Penicillins with extended spectrum與廣譜青霉素J01CE Beta-lactamase sensitive penicillins -內(nèi)酰胺酶青霉素敏感J01CF Beta-lactamase resistant penicillins -內(nèi)酰胺酶的耐青霉素J0

32、1CG Beta-lactamase inhibitors -內(nèi)酰胺酶抑制劑J01CR Combinations of penicillins, incl. beta-lactamase inhib青霉素類組合,含。 -內(nèi)酰胺酶抑制劑J01D OTHER BETA-LACTAMANTIBACTERIALS其它-內(nèi)酰胺類抗菌藥J01DB First-generation cephalosporins第一代頭孢菌素J01DC Second-generation cephalosporins第二代頭孢菌素J01DD Third-generation cephalosporins第三代頭孢菌素J01D

33、E Fourth-generation cephalosporins第四代頭孢菌素J01DF Monobactams單內(nèi)酰環(huán)類J01DH Carbapenems碳青霉烯類J01DI Other cephalosporins其他頭孢菌素J01E SULFONAMIDES AND TRIMETHOPRIM磺胺類藥物和甲氧芐啶J01EA Trimethoprim and derivatives甲氧芐啶及衍生物J01EB Short-acting sulfonamides短效磺胺類藥物J01EC Intermediate-acting sulfonamides中效磺胺類藥物J01ED Long-acting sulfonamides長效磺胺J01EE Combinations of sulfonamides andtrimethoprim,

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