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NervousSystem
神經(jīng)系統(tǒng)
★Organizations中樞神經(jīng)系統(tǒng)Centralnervoussystem(CNS)腦Brain脊髓Spinalcord周圍神經(jīng)系統(tǒng)Peripheralnervoussystem(PNS)腦神經(jīng)Cranialn.(12pairs)脊神經(jīng)Spinaln.(31pairs)內(nèi)臟神經(jīng)VisceralnervesMajorDivisionsofthe
CentralNervousSystemBrain腦Telencephalon端腦Diencephalon間腦Cerebellum小腦Midbrain中腦Pons腦橋Medullaoblongata延髓Spinalcord脊髓Brainstem腦干MajorDivisionsofthe
PeripheralNervousSystem
腦神經(jīng)Cranialnerves
(12pairs)脊神經(jīng)Spinalnerves
(31pairs)內(nèi)臟神經(jīng)VisceralnervesVisceralsensorynerveVisceralmotornerveSympatheticpart交感神經(jīng)Parasympatheticpart副交感神經(jīng)CellularOrganizationNeuron神經(jīng)元Cellbody胞體Axon軸突Dendrites樹突
Neuroglia神經(jīng)膠質(zhì)-glialcell膠質(zhì)細(xì)胞ClassificationofNeuronStructuralclassification雙極神經(jīng)元Bipolarneuronhasanaxonandadendrite假單極神經(jīng)元Pseudounipolarneuronhasacentralbranchandaperipheralbranch多極神經(jīng)元MultipolarneuronhasanaxonandtwoormoredendritesClassificationofNeuronsFunctionalclassification感覺神經(jīng)元Sensory(afferent)neuron運(yùn)動神經(jīng)元Motor(efferent)neuron聯(lián)絡(luò)神經(jīng)元Associationneuron
Reflex反射:areactionoftheorganismbythenervoussysteminresponsetoastimulusReflexarc反射弧:has5basiccomponents
Receptor
↓Sensoryneurons
↓CNS
↓Motorneurons↓Effector
★ReflexandReflexArc深反射(腱反射)-膝跳反射★BasicTerminologyinNervousSystemIntheCNSGraymatter灰質(zhì):
collectionofnervecellbodiesandtheirdendrites,graycolorduringfreshconditionCortex皮質(zhì):
theoutermostlayerofgraymatterincerebrumandcerebellumNucleus神經(jīng)核:
acollection(group)ofcellbodieswhichhavethesameshapeandfunction★BasicTerminologyinNervousSystemIntheCNSWhitematter
白質(zhì):collectionofnervefibers,whitecolorduringfreshconditionMedulla髓質(zhì):acentralcoreofwhitematterbeneaththecortexofcerebrumandcerebellumFasciculus(tract)纖維束:
abundleofnervefiberswhichhavethesameorigin,termination,pathwayandfunction★BasicTerminologyinNervousSystemReticularformation
網(wǎng)狀結(jié)構(gòu):
anadmixtureofcross-crossingfiberswithlargerorsmallergroupsofnervecellsoccupyingthemeshes★BasicTerminologyinNervousSystemInthePNSGanglion神經(jīng)節(jié):
acollectionofneuronalcellbodiesoutsidetheCNS.eg.Spinalganglion/gangliaNerve神經(jīng):
abundleofnervefibersheldtogetherbyconnectivetissuesheath.eg.SpinalnerveSpinalCord脊髓
ZhaoxiDingDepartmentofHumanAnatomyMedicalSchool,ShandongUniversitydingzhaoxi@★Position:Liesintheupper2/3ofthevertebralcanalContinuous
abovewithmedullaoblongata
atlevelofforamenmagnum
Ends
belowatthelowerborderofL1
inadultoratlevelofL3atbirthAbout40~45cminlengthWeightsabout30g.PositionofSpinalCord
Alongcylindricalstructureandslightlyflattenedanteroposteriorly★TwoenlargementsCervicalenlargement頸膨大correspondstotheC4-T1segmentssendsfiberstosupplytheupperlimbsLumbosacralenlargement腰骶膨大correspondstotheL2-S3segmentssendsfiberstosupplythelowerlimbs
ExternalFeaturesofSpinalCord★脊髓圓錐Conusmedullaris-the
lowerpyramidendofspinalcord★終絲Filumterminale-adelicatefilament,about20cminlength,prolongeddownwardfromtheapexoftheconusmedullaristothebackofthefirstsegmentofthecoccyx,continuousabovewiththatofthe
piamater.
★馬尾Caudaequina-collectionofrootsandrootletsofspinaln.(fromL2-5,S1-5,Co1)
aroundthefilum
terminale
belowtheconusmedullaris.Thesefibersgraduallydeclininginnumberfurtherdownasindividualpairsleavethespinalcolumn.
Lumbarpuncture(spinaltap)腰穿★ExternalFeaturesofSpinalCordFissureandsulciAnteriormedianfissure
前正中裂Posteriormediansulcus
后正中溝Anterolateralsulcus
前外側(cè)溝anterior(motor)rootsemergeserially
Posterolateralsulcus
后外側(cè)溝posterior(sensory)rootsenterspinalcord,eachbearaspinalganglionwhichconstitutesthefirstcell-stationofthesensorynervesPosteriorintermediatesulcus
后中間溝★SegmentsofSpinalCordAportionofthespinalcordthatgivesrisetoapairofspinalnerveconstitutesasegment.
Thereare31segments
8cervical12thoracic5lumbar5sacral1coccygealRelationshipofspinalCordSegments
toVertebralNumbers★RelationshipofspinalCordSegments
toVertebralNumbersSpinalsegmentsVertebrallevels(spines)C1~C4LieoppositethecorrespondingvertebraeC5~T4OnelowerinnumberthancorrespondingvertebraeT5~T8TwolowerinnumberthancorrespondingvertebraeT9~T12ThreelowerinnumberthancorrespondingvertebraeL1-L5T10~T12S1-S5andCoL1RelationshipofspinalCordSegments
toVertebralNumbersSpinalsegmentsVertebrallevels(spines)Uppercervicalregion(C1~C4)=C1~C4Lowercervicalandupperthoracicregion(C5~T4)-1=C4~T3Middlethoracicregion(T5~T8)-2=T3~T6Lowerthoracicregion(T9~T12)-3=T6~T9Lumbersegments=T10~T12Sacralandcoccygealsegments=L1InternalStructureofSpinalCord
Graymatter
灰質(zhì)Whitematter
白質(zhì)Centralcanal
中央管Reticularformation網(wǎng)狀結(jié)構(gòu)
★GrayMatterofSpinalCord
Anteriorhorn(column)
前角(柱)Posteriorhorn(column)后角(柱)Intermediatezone
中間帶Lateralhorn(column)
側(cè)角(柱)onlypresentinthethoracicandupperlumbersegmentsofthespinalcord(T1-L3)graycommissures灰質(zhì)連合
Anteriorgraycommissures
灰質(zhì)前連合Posteriorgraycommissures
灰質(zhì)后連合★GrayMatterofSpinalCordPosteriorhorn(column):Marginallayer緣層(posteromarginalnucleus后角邊緣核)Substantiagelatinosa膠狀質(zhì)SituatedattheapexofposteriorhornthroughoutthelengthofspinalcordConcernsthesensationsofpainandtemperatureNucleusproprius
后角固有核SituatedanteriortothesubstantiagelationnosathroughoutthelengthofspinalcordReceivesfibersthatareassociatedwiththesuperficialsensesNucleusthoracicus胸核
SituatedatthebaseofposteriorhornandextendingfromsegmentsC8~L3Associatedwiththedeepsenses(proprioceptiveendings)★GrayMatterofSpinalCordIntermediatezoneIntermediaolateralnucleus中間外側(cè)核(lateralhorn)ExtentsfromsegmentsT1~L3,ContainingsympatheticpreganglionicneuronsSacralparasympatheticnucleus
骶副交感核ExtentsfromsegmentsS2~S4,ContainingparasympatheticpreganglionicneuronsIntermediomedialnucleus中間內(nèi)側(cè)核
ThroughoutthelengthofspinalcordAssociatedwithvisceraafferentinformationAnteriorhorn(column):
★TwogroupsofnucleiMedialnucleargroup內(nèi)側(cè)核群:presentinmostsegmentsofspinalcord,innervatingaxialmusclesLateralnucleargroup外側(cè)核群:presentonlyincervicalandlumbosacralenlargements,innervatingupperandlowerlimbmusclesGrayMatterofSpinalCord
Anteriorhorn(column):Twokindsofmotorneurons
α-motorneuron:
largemultipolarneuron,innervatesskeletalmuscles,producingcontractionofmusclesγ-motorneuron:
smallermultipolarneuron,innervatesintrafusalmusclefibersofneuromuscularspindles,regulatingmusculartonusInterneuron—Renshaw’scell:negativefeedbackmechanismRexed’slamina板層PosteriorhornisformedbylaminaⅠtoⅥ;IntermediatezonecorrespondingtolaminaⅦ;AnteriorhorniscomposedlaminaeⅧandⅨ;laminaⅩisthegraymattersurroundingthecentralcanal.ImportantSubdivisionsofGrayMatterRegionLaminaNucleusPosteriorhornⅠMarginallayerⅡSubstantiagelatinosaⅢ,ⅣNucleuspropriusIntermediatezoneⅦNucleusthoracicus(C8~L3)ⅦIntermediolateralnucleus(T1~L3)ⅦSacralparasympatheticnucleus(S2~S4)ⅦIntermediomedialnucleusAnteriorhornⅨMotorneuronWhiteMatterofSpinalCordWhitematter白質(zhì)
containsthreekindsoffibers:AscendingfibersDescendingfibersFasciculusproprius固有束WhiteMatterofSpinalCordAnteriorfuniculus前索Lateralfuniculus外側(cè)索Posteriorfuniculus后索Anteriorwhitecommissure白質(zhì)前連合AscendingTractsFasciculuscuneatus楔束Posteriorspinocerebellartr.脊髓小腦后束Anteriorspinocerebellartr.脊髓小腦前束Spinothalamic
tract脊髓丘腦束Fasciculusgracilis薄束★Fasciculusgracilis薄束LocatedinthewholeposteriorfuniculusbelowT4andonlyinthemedialpartaboveT4ArisefromthespinalgangliabelowsegmentT4(centralprocessofspinalganglia)TerminateinGracilenucleusinmedullaoblongataConveyproprioceptiveandfinetouchsensationfromlowerpartoftrunkandlowerlimbonthesamesideSpinalganglion
1°neuron
Gracilenuclei
2°neuron
T4FGFG★FasciculusCuneatus楔束LocatedinthelateralpartofposteriorfuniculusaboveT4ArisefromthespinalgangliaabovesegmentT4(centralprocessofspinalganglia)TerminateincuneatenucleusinmedullaoblongataConveyconsciousproprioceptiveandfinetouchsensationfromupperpartoftrunkandupperlimbonthesamesideSpinalganglion
1°neuron
cuneatenuclei
2°neuron
T4FCFGLowerlimbupperlimbFasciculusgracilisFasciculuscuneatusCortexofcerebrumdiencephalonMedialleminecusGracileandcuneateNu.ClinicalnoteLossofproprioceptivesensationonthesamesideLossoffinetouchsensationonthesamesideSensorydystaxia(Incoordination)感覺性共濟(jì)失調(diào)★Spinothalamictract脊髓丘腦束LocatedintheLateralandanteriorfuniculusArisefromtheneuronsincontralaterallaminaeI,IV~VIIabout1-2segmentbelowTerminateinDorsalthalamusConveypain,temperatureandsimpletouchsensationoftrunkandlimbsSpinalganglia1°neuron
LaminaⅠ,Ⅳ~Ⅶ
2°neuron
VPL
3°neurons
ASTLSTClinicalnote
Analgesiaandthermo-anesthesiaontheoppositesideofthebody(bellowthedamagedsegment)Spinocerebellartracts脊髓小腦束LocatedinthesuperficialpartoflateralandanteriorfuniculiConveyunconsciousproprioceptionfromlowerlimbandlowerportionoftrunkonthesamesidetothecerebellumContain:Posteriorspinocerebellartract脊髓小腦后束Anteriorspinocerebellartract脊髓小腦前束Posteriorspinocerebellartract脊髓小腦后束LocatedintheposteriorandsuperficialpartoflateralfuniculusaboveL3ArisefromthenucleusthoracicusonhomolateralsideTerminateinsuperiorandinferiorvermisofcerebellumConveyunconsciousproprioceptionfromlowerlimbandlowerportionoftrunkonthesamesideSpinalganglion1°neuron
NucleusThoracicus2°neuronAnteriorspinocerebellartract脊髓小腦前束LocatedanteriortotheposteriorspinocerebellartractinthesuperficialpartoflateralfuniculusArisemainlyfromtheneuronsincontralaterallaminaⅤ~ⅦTerminateinsuperiorvermisofcerebellumConveyunconsciousproprioceptionfromlowerlimbandlowerportionoftrunkontheoppositesideSpinalganglion
1°neuronLaminaⅤ-Ⅶ2°neuron
AscendingtractsTractSiteoforiginFuniculusTerminationFunctionFasciculusgracilisSpinalgangliabelowsegmentT5PosteriorGracilenucleusConsciousproprioceptive(vibratorysense,andmusclejointsense)andfinetouchsensationoftrunkandlimbsFasciculuscuneatusSpinalgangliaabovesegmentT4CuneatenucleusPosteriorspinocerebellartractHomolateralnucleusthoracicusLateralCerebellumUnconsciousproprioceptionfromlowerlimbandlowerportionoftrunkAnteriorspinocerebellartractContralateralLaminaeⅤ~ⅦSpinothalamic
tractLaminaeⅠ,Ⅳ~ⅦLateralandanteriorDorsalthalamusPain,temperatureandcrudetouchsensationoftrunkandlimbs上行傳導(dǎo)束名稱起位置止功能薄束T5以下的脊神經(jīng)節(jié)后索薄束核傳導(dǎo)同側(cè)軀干和肢體的本體感覺(肌、腱、關(guān)節(jié)的位置覺、運(yùn)動覺和震動覺)和精細(xì)觸覺楔束T4以上的脊神經(jīng)節(jié)楔束核脊髓小腦后束同側(cè)胸核外側(cè)索小腦下肢和軀干下部的非意識性本體感覺脊髓小腦前束對側(cè)板層Ⅴ~Ⅶ脊髓丘腦束板層Ⅰ,Ⅳ~Ⅶ外側(cè)索和前索背側(cè)丘腦痛、溫覺、粗觸覺DescendingTractsLateralcorticospinaltract皮質(zhì)脊髓側(cè)束Anteriorcorticospinaltract皮質(zhì)脊髓前束Rubrospinaltract紅核脊髓束Vestibulospinaltract前庭脊髓束Reticulospinaltract網(wǎng)狀脊髓束Mediallongitudinalfasciculus內(nèi)側(cè)縱束Tectospinaltract頂蓋脊髓束★Corticospinaltracts皮質(zhì)脊髓束ArisefromthepyramidalneuronsincerebralcortexLateralcorticospinaltract皮質(zhì)脊髓側(cè)束Anteriorcorticospinaltract皮質(zhì)脊髓前束AnterolateraltractofBarne★L(fēng)ateralcorticospinaltract皮質(zhì)脊髓側(cè)束LocatedindeeppartoflateralfuniculusArisefromthepyramidalneuronsincontralateralcerebralcortexthroughthedecussationofpyramidtractFibresarrangement
superficialtoprofoundS,L,T,CTerminateinLaminaeⅣ~Ⅸofanteriorhorn,C(55%),T(20%),LS(25%)ConveymotorsignaltocontrolVoluntarymovement(musclesofthelimbs)Clinicalnotes
disabilityofvoluntarymovement(paralysis)
★anteriorcorticospinaltract皮質(zhì)脊髓前束LocatedinmedialpartofanteriorfuniculusArisefromthepyramidalneuronsincontralateralcerebralcortexthroughthedecussationofpyramidtractTerminateinLaminaeⅣ~ⅨonbothanteriorhornConveymotorsignaltocontrolvoluntarymovement(musclesofthetrunk)DescendingtractsTractSiteoforiginFuniculusTerminationFunctionLateralcorticospinalCerebralcortexLateralLaminaeⅣ~ⅨanteriorhornVoluntarymovementAnteriorcorticospinalCerebralcortexAnteriorRubrospinalRednucleusLateralLaminaeⅤ~ⅦFacilitatesactivityofflexormusclesVestibulospinalHomolateralvestibularnucleiAnteriorLaminaeⅦ~ⅧFacilitatesactivityofextensormusclesReticulospinalReticularformationAnteriorandlateralLaminaeⅦ~ⅧVoluntarymovementMediallongitudinalfasciculusVestibularnucleiAnteriorLaminaeⅦ~ⅧCoordinateneckwitheyemovementTectospinalSuperiorcolliculusAnteriorLaminaeⅥ~ⅧFasciculuspropriusSpinalcordAnterior,lateralandposteriorSpinalcordIntrinsicreflexmechanismofspinalcord
下行傳導(dǎo)束名稱起位置止功能皮質(zhì)脊髓側(cè)束大腦皮質(zhì)外側(cè)索板層Ⅳ~Ⅸ前角隨意運(yùn)動皮質(zhì)脊髓前束大腦皮質(zhì)前索紅核脊髓束紅核外側(cè)索板層Ⅴ~Ⅶ興奮屈肌前庭脊髓束同側(cè)前庭神經(jīng)核前索板層Ⅶ~Ⅷ興奮伸肌網(wǎng)狀脊髓束網(wǎng)狀結(jié)構(gòu)前索和外側(cè)索板層Ⅶ~Ⅷ協(xié)調(diào)隨意運(yùn)動內(nèi)側(cè)縱束前庭神經(jīng)核前索板層Ⅶ~Ⅷ協(xié)調(diào)頭頸部和眼的運(yùn)動頂蓋脊髓束中腦上丘前索板層Ⅵ~Ⅷ固有束脊髓前索
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