更年期管理與絕經(jīng)婦女激素治療01

更年期管理與絕經(jīng)婦女激素治療(一)絕經(jīng)婦女需要激素治療內(nèi)容什么是絕經(jīng)絕經(jīng)對女性的影響：危害激素補充治療的好處：利益女性壽命增長絕經(jīng)年齡時間年齡（年）國外：48-51歲北京：49.4±3.4歲“絕經(jīng)”是一個亟待解決的問題！人口統(tǒng)計資料（2005）

合計0.01

2509810331995+0.060.030.091104047851582590-940.210.120.3336107204755658285-890.530.390.92899786613215611080-840.910.801.7115448713568429017175-791.361.322.6823092822402745495570-741.641.683.3227792928616656409565-691.922.023.9332579134251966831060-642.622.725.3444501446242190743555-593.623.677.28614170622759123692950-54女男總數(shù)女男總數(shù)年齡百分比人口數(shù)

中國人口統(tǒng)計年鑒（2005）12.88中國人口總數(shù)1,300,000,00050歲以上所占比例:12.88%絕經(jīng)人口約:167,440,000圍絕經(jīng)期卵泡數(shù)量急劇減少BurgerHG.Medicin2006;34(1):27-30

原始卵泡數(shù)量年齡（歲）“絕經(jīng)...是一種激素缺乏狀態(tài)”KimW.EndocninolgyofmenopauseEditorRatnamSS,CampanaA.MedicalForumIntermational(1998)33-36KlingaKetal.Matioitas4(1982)9-17NotelovitzM.GynecolEndocrinol12(1998)249-25814013012010080604020322824201612844446 50485254565860FSH,雌二醇+雌酮不同年齡的變化(n=257)

(pg/ml)(ng/ml)圍絕經(jīng)期雌二醇絕經(jīng)后期FSH雌酮內(nèi)容什么是絕經(jīng)絕經(jīng)對女性的影響：危害激素補充治療的好處：利益血管舒縮癥狀睡眠障礙月經(jīng)紊亂心境變化陰道萎縮性欲減退皮膚皺縮骨質(zhì)疏松癥動脈粥樣硬化冠心病腦血管疾病40歲50歲60歲與年齡、絕經(jīng)相關(guān)的癥狀和疾病70歲絕經(jīng)北京地區(qū)更年期癥狀的患病率YingLi,QiYu,LiangkunMa,etal.PrevalenceofdepressionandanxietysymptomsandtheirinfluencefactorsduringmenopausaltransitionandpostmenopauseinBeijingcity.Maturitas61(2008)238–242圍絕經(jīng)期抑郁癥狀發(fā)生率23.8％YingLi,QiYu,LiangkunMa,etal.PrevalenceofdepressionandanxietysymptomsandtheirinfluencefactorsduringmenopausaltransitionandpostmenopauseinBe