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生物化學與分子生物學(MBBS)智慧樹知到期末考試答案+章節(jié)答案2024年錦州醫(yī)科大學Thecrosslinkbetweenglycogenesisandglycogenolysisis()
答案:glucose1-phosphateDirectbilirubinissynthesizedat:()
答案:liverOxidativephosphorylationoccursin:()
答案:mitochondriaSubstratelevelphosphorylationisinvolvedin()
答案:1,3-bisphosphoglycerate→3-phosphoglycerateWhichofthefollowingaminoacidcannotproduceonecarbonunit?()
答案:ValineWhatisgeneexpression?()
答案:transcription,translationWhichisanintermediateonthepathwayforsynthesisofketonebodiesandcholesterol?()
答案:HMG-CoAThecontentofwhichofthefollowingelementisclosetoeachotherinvariousprotein?()
答案:NInwhichfollowingconditionsareketonebodiessynthesisgreatlyaccelerated?()
答案:fatmobilizationisenhancedhesub-cellsiteofcholesterolsynthesisis()
答案:cytosol+endoplasmicreticulumWhichofthefollowinglinkthecoreparticleofnucleosome?()
答案:H1WhichoffollowingisindependentofKm?()
答案:enzymeconcentrationWhichofthefollowingmetabolicreactioncannotoccurinliver?()
答案:utilizationofketonebodyThekineticsofenzymaticreactionisthestudyon:()
答案:thevelocityofenzymaticreactionsandinfluenceofvariouselementsonitWhichofthefollowingisnotconcernedwiththecholesterolbiosynthesis?()
答案:NADH+H+Theeffectoftemperatureontherateofenzymaticreactionsis()
答案:eachenzymehasanoptimumtemperatureatwhichitoperatesatmaximalefficiencyWhichoffollowingisthemajororgantoregulatetheconcentrationofglucose?()
答案:liverWhichofthefollowingDNAhasthelowestTm?()
答案:A-Tis80%Thetranslationalinitiationcomplexincludes()
答案:ribosomal+mRNA+Met-tRNAiMetThemajorfactortocontroloxidativephosphorylationinnormalphysiologicalconditionis:()
答案:ADPlevelWhichofthefollowingistheproductofthereplicationcontinuously:()
答案:leadingstrandWhichofthefollowinghormonecanacceleratefatmobilization?()
答案:allotherDuringtheelongationofpolypeptidechaininproteinbiosynthesis,whichsitecanreceipttheaminoacyl-tRNA()
答案:aminoacylsiteWhichoffollowingisnotthecharacteristicsofenzymaticreactions?()
答案:proximityandorientationTheα-subunitofGproteinhavetheactivityof:()
答案:GTPaseMalonatewithsuccinateforsuccinatedehydrogenaseistheclassiccaseof:()
答案:competitiveinhibitionWhichoffollowingisnotcorrectaboutcompetitiveinhibitor?()
答案:itcombineswiththeenzymecovalentlyWhichofthefollowingisnotcorrectaboutprimarybileacid?()
答案:allprimarybileacidarefreeWhichofthefollowingisthecharacteristicofRNA-pol?()
答案:thetranscriptiveproductissynthesizedfrom5′→3′Therawmaterialofcholesterolinthebodyis()
答案:acetyl-CoAWhichofthefollowingaminoacidcontainhydroxylgroup?()
答案:Ser,ThrEveryintegrityproteinmustprocess:()
答案:tertiarystuctureWheredoesdenovosynthesisofpurinenucleotidemainlytakeplace?()
答案:liverThekineticpropertyofnon-competitiveinhibitionis:()
答案:Kmisunchanged,VmaxisdecreasedWhichofthefollowingistheenzymeofpeptidebondformation:()
答案:peptidyltransferaseWhichofthefollowingdonottakepartinthebiotransformationofhemeinliver?()
答案:glucoseDifferentenzymescatalyzesequentialreactionsinthesamepathwayareboundtogetherin()
答案:multienzymecomplexesEnergyforbraininlongstarvationmainlycomesfrom()
答案:ketonebodiesoxidationAfterphosphorylationofglycogensynthaseandphosphrylase()
答案:glycogensynthaseisinactive,phosphrylaseisactiveTheprimarystructureofDNAisthesequenceofitsnucletideresidueslinkedby()?
答案:3’,5’-phosphodiesterbondsWhichofthefollowingarerelatedwithDNAreplicationinitiation?()
答案:topoismerase###helicase###primase###SSBWhichoffollowingiscorrectaboutenzyme?()
答案:enzymesarebiocatalyststhatcatalyzethemultipledynamicprocessesinthebody###enzymesarehighlyspecifictothereactionstheycatalyzeWhichoffollowingiscorrectaboutcovalentmodification?()
答案:havetwoforms:activeformandinactiveform###itmakereactionamplified###itisafastregulation###controlledbyhormoneWhichofthefollowingarethemaintransportationstyleofammoniabetweentissues?()
答案:Alanine###glutaminePropertiesofbindingofHandRare:()
答案:highlyspecificity###highlyaffinity###reversiblebinding###saturationTheendproductofgeneexpressioncouldbe:()
答案:RNA###protein###polypeptidechainTheDNArepairingtypeinclude:()
答案:ExcisionrepairingneedUvrABC###Recombinationrepairing###ExcisionrepairingneedXPprotein###SOSrepairing###LightrepairingWhichofthefollowingabouttrans-actingfactorsarecorrect?()
答案:havemanykinds###couldbindspecialcis-actingelements###areproteinWhichofthefollowingarethepropertiesofα-helixstructure?()
答案:thehelixisrighthanded###thehelixriseupspirallyaroundcentralaxis###onepitchis0.54nm###3.6residuespercircleWhichofthefollowingcouldcatalizethesynthesisofphosphodiesterbond?()
答案:reversetranscriptase###topoismerase###telomerase###DNAligase###DNA-polTheplasmidusedinDNArecombinationtechologyis:()
答案:theindependenthereditaryunitoutsideofthebecterialgenomicDNAAcertainrestricionendonucleasecutDNAbymeansof5′…GGGGGG▼AATTCC…3,’andwillgenerate()
答案:5′salient(突出的)StickyendAcertainrestricionendonucleasecutDNAbymeansofGGG▼CGCCC,andwillgenerate()salientstickyend:()
答案:2nucleotidesWhichofthefollowingcouldnotbeusedasvectorforDNAcloning?()
答案:BacterialgenomeDNAToconstructcDNAlibraryneed:()
答案:reversetranscriptaseandmRNAtemplateWhichofthefollowingisthemostgeneralcharacteristicofthevectorneededinDNAcloning?()
答案:selfreplicationabilityTheprocessofDNAcloningdoesnotinclude()
答案:probesynthesisfortargetgenedetectionWhichofthefollowingistheendthatT4ligasecatalizetolinktogether?()
答案:5′-Pand3′-OHGeneralrecombinationisalsocalled:()
答案:HomologousrecombinationTheoptimalcellsystemtoexpresshumanproteinis()
答案:mammaliacellexpressionsystemWhichofthefollowingaboutC-onciscorrect?()
答案:expressionproductofoncogeneisfucntionalproteininnormalcellphysiologialaction###c-onccouldbedetectedinnomalhigheranimalcells###v-oncisnucleotidesequenceexistedintumorvirusWhichofthefollowingaboutC-oncisnotcorrect?()
答案:alsonamedvirus-oncogene###existinRNAvirus###existinviralDNAWhichofthefollowingbelongtoanti-oncogene?()
答案:p53Whichofthefollowingarenottheexpressionproductofoncogene?()
答案:cis-actingelementWhichofthefollowingelementcouldactivateoncogene?()
答案:pointmuationofoncogeneWhichofthefollowingdoesnotbelongtooncogene?()
答案:RbWhichofthefollowingbelongtooncogenexpressionproduct?()
答案:growthfactorreceptors###growthfactor###intranucleartranscriptionfactor###signalmoleculorparticipatecellularsignaltransductionWhichofthefollowingaboutoncogeneisnotcorrect?()
答案:normalcellshavenooncogeneTheoncogenewouldbeactivatedinthefollowingofsituation:()
答案:genemutation###proto-oncogeneamplification###chemcialcarcinogensexistence###radioactiveray###beinfectedbycancer-inducingvirusWhichofthefollowingcouldinducecellcanceration?()
答案:genedamagedbyphysicalandchemicalcarcinogenicagent###virus-oncogeneincorporatethecellandexpression###pointmutationofoncogene###thelostorinactivationofanti-oncogeneWhichofthefollowingbelongtooncogene?()
答案:ras###sis###erb-BWhichofthefollowingaboutpropertiesofbindingofhormoneandreceptorisnotcorrect()。
答案:covalentbondingTheαsubunitofGproteinhavetheactivityof()。
答案:GTPaseWhichofthefollowingdoesnotbelongtosecondmessenger()。
答案:PIP2WhichofthefollowingdoesnotparticipateinAC-cAMP-PKApathway()。
答案:cGMPGproteinisreferredto()。
答案:GTPbindingproteinWhichofthefollowingdonotparticipateincellularsignaltransduction()。
答案:NAD+SignaltransductionpathwaymediatedbyEGFreceptorconsistof()。
答案:ERK###RTK###MEK###Ras###RafThechemicalnatureofintracellularreceptorsis()。
答案:DNAbindingproteinWhichcancauseendoplasmicreticulumreleaseCa2+()。
答案:IP3Extracellularchemicalmoleculesinclude()。
答案:endocrinehormones###paracrinesignals###neurotransmittersWhichofthefollowinggeneraltranscriptionfactorscanrecognizeandbindtoTATAboxdirectly()。
答案:TFⅡDOperonsdonotinclude()。
答案:trans-actingfactorWhichofthefollowingbelongstoacis-actingelement()。
答案:enhancerWhichofthefollowingdoesnotbelongtogeneexpression()。
答案:ThereplicationofRNAThestructureoflacoperonconsistof()。
答案:onepromoter###threestructuralgenes###Igene###oneoperatorWhichofthefollowingbelongstoatrans-actingfactor()。
答案:transcriptionfactorWhichinducesthetranscriptionoflacoperon()。
答案:allolactoseWhenthetryptophanlevelsarehigh,thetryptophanoperonisregulatedby()。
答案:attenuator###negativeregulation###repressorproteinWhichisboundbyRNApolymeraseandinitiatestranscription()。
答案:promoterThegeneralregulatorypointofgeneexpressionis()。
答案:transcriptioninitiationThesubstancethatisnotneededforproteinbiosynthesisis()。
答案:DNAWhichofthefollowingtRNAanticodonismatchedwithmRNAcodonACG()。
答案:CGUAminoacyl-tRNAsynthetasehasspecificityfor()。
答案:aminoacidandtRNAWhichenzymecatalyzestheformationofpeptidebond()。
答案:transpeptidaseWhichofthefollowingmaterialcancarrythegeneticinformationofDNAtothecytoplasmandtoguidethebiosynthesisofprotein()。
答案:mRNAWhatcomponentsareneededfortheribosomecycle()。
答案:elongationfactor###mRNA###aminoacyl-tRNA###ribosome###GTPTheintroductionofeukaryoticsecretoryproteinsintotheendoplasmicreticulumis()。
答案:signalpeptideTheenergyrequiredforpeptidechainelongationinprokaryoticproteinbiosynthesisis()。
答案:GTPInthecharacteristicsofthecodons,theframeshiftmutationisrelatedto()。
答案:non-punctuationandnonoverlappingSubstancesinvolvedinproteinbiosynthesisare()。
答案:ATP###aminoacid###tRNA###GTP###mRNAThetranscriptofRNApolymeraseIineukaryotesis()
答案:45SrRNAWhichsubunitofRNApolymeraseisthespecificbindingsiteofRifampicininprokaryotes?()
答案:βsubunitThetranscriptoftemplate5'-ACTAGTCAT-3'is()
答案:5'-AUGACUAGU-3'TheprimaryroleofRNApolymeraseⅢistosynthesis()
答案:tRNAand5SrRNAWhichoneiscorrectabouttheexon?()
答案:TheDNAsequencethatistranscribedandtranslatedWhichsubunitofRNApolymerasecanrecognizethetranscriptionstartsiteinprokaryotes?()
答案:σsubunitThebindingsiteofTFⅡDis()
答案:TATAboxFeather-likestructureoftranscriptionunderelectronmicroscopeindicates()
答案:translationwasinitiatedbeforethetranscriptiontermination.WhichonecaninhibitprokaryoticRNApolymerasespecifically?()
答案:RifampicinRNAholoenzymeincludesσsubunit,itbindswithDNAtemplatestrandattheinitiationofthetranscription.Intheelongationstage,theσsubunitwill()
答案:dissociatefromtheholoenzymeintheelongationstage.WhichofthefollowingisthelargerfragmentofDNApolⅠ?()
答案:KlenowfragmentThematerialsofDNAsynthesisare:()
答案:dATP,dGTP,dCTP,dTTPWhichoftheseenzymeisnotconcernedwithDNAreplication?()
答案:RNAdependentDNApolymeraseTheprokaryoticDNA-polcoreenzymeismadeupwith()?
答案:αεθWhichofthefollowingserveastheenzymeinmitochondriaDNAreplication?()
答案:DNApolγInDNAreplication,whatisthereasonofOkazakifragmentgenerated?()
答案:thedirectionofreplicationisdifferentwiththedirectionofunwindingDNAandRNAarecomposedoffourtypesofdeoxyribonucleotidesandribonucleotides,respectivelylinkedwith()?
答案:3’,5’-phosphodiesterWhichofthefollowingistheproductofthereplicationdiscontinuously?()
答案:OkazakifragmentWhichofthefollowingcouldproofreading,DNArepairing,fillingofgaps?()
答案:DNApolⅠIntheinitiationofDNAreplication,theproperorderthatfollowingenzymeandproteinactingis?1,DNA-polⅢ2,SSB3,primase4,helicase()
答案:4,2,3,1IntheprokaryoticDNAreplication,whichofthefollowingisNOTneeded?()
答案:PCNAThecommondonorsoftheconjugatedsubstancesare()inthephaseIIreactionoftheliver.
答案:UDPGA###acetylCoA###PAPS###SAMWhichofthefollowingisnotthedonatorofbiotransformation?()
答案:UDPGWhichisthemostimportantenzymetakingpartintheoxidationreactionofthebiotransformation?()
答案:monooxygenaseThemostimportantphaseIreactionofthebiotransformationis()
答案:oxidationreactionThemostrelevantofthebiotransformationprocessinliveris()
答案:cytochromeP450Themostsignificanceofthebiotransformationisto().
答案:increasethesolubilityofthenon-nutritionalsubstanceandeliminatefromthebodyThemostimportantphaseIIreactioninthebiotransformationis().
答案:combinewithglucuronicacidNon-nutritionalsubstancecan()afterbiotransformation.
答案:decreasethedrugactivity###decreasethetoxicity###excretefromthebileacidorurine###increasethewatersolubilityWhichofthefollowingcanprovideactivemethylgroup?()
答案:SAMWhichofthefollowingcanprovideactivesulphate?()
答案:PAPSWhichofthefollowingistheenzymethatcatalyzethesynthesisofuricacid?()
答案:xanthineoxidaseWhichofthefollowingisnotthedirectmaterialofdenovosynthesisofpurinenucleotide?()
答案:glutamateWhichofthefollowingsubstancedirectlylinknucleotidesynthesisandglucosemetabolism?()
答案:glucose-6-phosphateWhichofthefollowingisthemethylgroupdonorofTMP?()
答案:N5,N10-CH2-FH4Whichofthefollowingistheendproductionofpurinenucleotidecatabolicmetabolism?()
答案:uricacidWhichofthefollowingmaterialcouldprovideC4andC5forpurinering?()
答案:GlycineWhichofthefollowingistheanalogueofazaserine?()
答案:glutamineWhichofthefollowingisdirectlyreduced,andproducedeoxynucleotide?()
答案:NDPWhichofthefollowingisthecommonmaterialforthesynthesisofpyrimidineandpurinenucleotide?()
答案:glutamineWhichofthefollowingisfirstsynthesizedintheprocessofdenovosynthesisofpurinenucleotide?()
答案:IMPIntheprocessofureacycle,whichofthefollowingsubstancecangooutmitochondrion?()
答案:citrullineWhichofthefollowingisnotproducedbyTyr?()
答案:PheWhichofthefollowingisnotonecarbonunit?()
答案:CO2Inthesynthesisofurea,oneNcomefromNH3,anotherNcomefrom()directly?
答案:AspWhichofthefollowingisnottheoutletofα-ketoacidthatproducedbydeaminationofaminoacid?()
答案:beconvertedtoessentialamminoacidWhichofthefollowingisthecarrierofonecarbonunit?()
答案:FH4WhichofthefollowingisthedirectdonorofCH3?()
答案:SAMWhichofthefollowingisthestorageandtransportationstyleofammonia?()
答案:GlnWhichofthefollowingisonlyketogenicaminoacid?()
答案:LeucineWhichofthefollowingaminoacidcanproducePAPS?()
答案:cysteineThemajorfunctionofHDLis()
答案:reversecholesteroltransportCholineisactivatedintheformof(),beforeitentersdiacylglycerolpathway.
答案:CDP-cholineThelipoproteinthattransferendogenouscholesterolis:()
答案:LDLWhichoffollowingdoesnotutilizeketonebodies?()
答案:liverWhichisthemajorformthattransportsexogenousTAGstothecirculation?()
答案:CMWhichisthemajorformthattransportsendogenousTAGsfromthelivertothetissues?()
答案:VLDLWhichisnotrequiredinβ-Oxidationoffattyacids?()
答案:NADP+Intheliver,()istherate–limitingenzymeonthepathwayforsynthesisofcholesterol.
答案:HMGCoAreductaseHowmanymolsofATPareyieldedwhen1molstearicacid(18C)isoxidizedtoCO2andH2O?()
答案:120NADPHinfattyacidsynthesiscomesfrom:()
答案:pentosephosphatepathwayThecharacteristicofbiologicaloxidationis()
答案:energyreleasedgraduallyandhighavailabilityWhichofthefollowingenzymeusesFADasprotheticgroup?()
答案:succinatedehydrogenaseThecoenzymeofα-glycerophosphatedehydrogenaseinmitochondriais:()
答案:FADWhichofthefollowingmetabolicprocessiscompletedinmitochondriontotally()
答案:oxidativephosphorylationWhichoffollowingisthecarrierofNADHfromcytosoltomitchondria?()
答案:malateWhichofthefollowingisnottheenergy-richcompound?()
答案:2,3-bisphoglycerateWhichagentisaninhibitorofelectrontransportatComplexⅢ?()
答案:antimycinAHowmanyATPswillbeproducedwhen1cytosolicNADHistransportedintothemitochondriabyα-glycerophosphateshuttle?()
答案:1.5TheorderofNADHrespiratorychainis:()
答案:NAD+→complexⅠ→CoQ→complexⅢWhichofthefollowingisthemostimportantelementintheregulationofoxidativephosphorylation?()
答案:[ADP]/[ATP]Whichismetabolizedthroughboththeglycolyticpathwayandthepentosephosphatepathway?()
答案:glucose6-phosphateHowmanyATPsareproducedbytheoxidationofamoleculeofaceylCoAviathecitricacidcycle?
答案:13Substrate-levelphosphorylationincitrateacidcycleis:()
答案:succinyl-CoA→succinateTheend-productofglycolysisis:()
答案:lactateThekeyenzymeoftheglycolysisis:()
答案:pyruvatedehydrogenaseWhyerythrocytesmetabolizeglucosebyanaerobicglycolysis?()
答案:lackofmitochondriaWhichoffollowingisnotthekeyenzymeinaerobicoxidationofcarbohydrate?()
答案:succinatedehydrogenase1moleculeofpyruvatewhichisoxidizedcompletelymaygenerate()moleculesofATP.()
答案:12.5WhichoffollowinggenerateFADH2afterdehydrogenation?()
答案:succinateWhatarethemostimportantproductsthecellsgeneratebymeansofthepentosephosphatepathway?()
答案:ribose-5-phosphateandNADPHWhichoffollowingisnotcorrectaboutLDHisoenzymes?()
答案:havethesameKmtothesamesubstrateTherelationshipbetweencompetitiveinhibitorandsubstrateisthattheyhave:()
答案:similarstructureWhichoffollowingisnotcorrectaboutKm?()
答案:KmisindependentofenzymestructureWhichoffollowingiscorrectaboutcharacterofenzyme?()
答案:allgroupsinactivesitearetermedtheessentialgroupsWhichoffollowingisnotcorrectaboutallostericenzyme?()
答案:allostericeffectorbindstoactivesiteofenzymeIsoenzymesareenzymesthat:()
答案:catalyzethesamereactionWhichoffollowingisnotcorrectaboutactivesiteofanenzyme?()
答案:itisformedbygroupsthatprimarystructureisclosetoeachotherinthepolypeptidesequenceWhichoffollowingisnotcorrectaboutcovalentmodification?()
答案:activityofenzymeincreasedafterphosphorylatedSpecificityofenzymerefersto
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