Berberine-hemisulfate-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEBerberine(hemisulfate)(Standard)Cat.No.:HY-N0716ARCASNo.:316-41-6分子式:C??H??NO?.?/?O?S分子量:384.4作用靶點(diǎn):Antibiotic;Topoisomerase;Autophagy;Bacterial;ReactiveOxygenSpecies;Apoptosis;PI3K;Akt;Caspase;JNK;AP-1;NF-κB作用通路:Anti-infection;CellCycle/DNADamage;Autophagy;Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB;Apoptosis;PI3K/Akt/mTOR;MAPK/ERKPathway儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Berberine(hemisulfate)(Standard)是Berberine(hemisulfate)的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Berberinehemisulfate是Berberine(HY-N0716)的半硫酸鹽形式。Berberinehemisulfate是可以從中草藥黃連中分離出來(lái)的生物堿。Berberinehemisulfate具有抗炎、抗菌、抗腫瘤、心血管保護(hù)和神經(jīng)保護(hù)活性[1][2][3REFERENCESCaiY,etal.Berberineinhibitsthegrowthofhumancolorectaladenocarcinomainvitroandinvivo.JNatMed.2014Jan;68(1):53-62.CuiHX,etal.PreparationandEvaluationofAntidiabeticAgentsofBerberineOrganicAcidSaltsforEnhancingtheBioavailability.Molecules.2018Dec28;24(1):103.BoberekJM,etal.,GeneticevidenceforinhibitionofbacterialdivisionproteinFtsZbyberberine.PLoSOne.2010Oct29;5(10):e13745.RemppisA,etal.,RhizomaCoptidisinhibitsLPS-inducedMCP-1/CCL2productioninmurinemacrophagesviaanAP-1andNFkappaB-dependentpathway.MediatorsInflamm.2010;2010:194896.BaeJ,etal.,Berberineprotects6-hydroxydopamine-inducedhumandopaminergicneuronalcelldeaththroughtheinductionofhemeoxygenase-1.MolCells.2013Feb;35(2):151-7.YeY,etal.,EfficacyandSafetyofBerberineAloneforSeveralMetabolicDisorders:ASystematicReviewandMeta-AnalysisofRandomizedClinicalTrials.FrontPharmacol.2021Apr26;12:653887.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3