寄生蟲(chóng)--肺吸蟲(chóng).ppt

1、paragonimus,Typical character,Female genital system:,Ovary and womb are at the same level on midline,Male genital system:,Testes are located at the junction of the posterior fourth of the body,The main parasite including:,Paragonimus westermani 2. Paragonimus skrjabini 3. Paragonimus heterotremus,Pa

2、ragonimus westermani,Oral sucker,Vetral sucker,Cecum,Uterus,Ovary,Testes,Excretory bladder,1.adult,Morphology,2. Egg,Egg,operculum,ovotid,yolk cell,Live cycle,Adult,egg,Eggs pass into water in feces,miracidium,sporocyst,cercaria,All these stage are,growed in the snail,leave snail and are eated By cr

3、ab,metacercaria,Man is infective by eating the raw crab .,worm,Worm move through The internal organs,adult,Worms moving way:,Small intestine,Abdominal cavity,Thoracic cavity,Lung,Pass the diaphragmatic surface,Are hatched in the duodenum,Melania,Crab,Crayfish,Attention:,1. Ectopic parasitism,Subcuta

4、neous, liver, brain ,spinal cord, eye.,Transport host:,Some parasite worm invade abnormal host ,it can not become adult,it maintain the worm stage,but when it has chance to invade normal host it become adult ,the abnormal host called it.,Pathogenesis and clinical manifestation,1. Acute period (cause

5、 by young worm),The young worms activity cause the partial tissue and organ damaged,bleed,inflamation, the damaged area became a hole and then lead to the tissue ibous,adhesions,particularly the liver.,2.Chronic period,Pathogenesis in lung,The adults mechanical spoil And its secretion and excretion,

6、inflammation,abscess,cyst,When the adult die or move Other place or the content Remove or bsorbed,Granulation tissue formed,fibrous,Clinical symptom,The patient feel chest discomfort cough, hemoptysis(咳血) , Sputum is brown-flake, Egg is often found in the sputum,B. Ectopic parasitism,Subcutaneous-cy

7、sts in the skin Brain-brain discomfort , epilepsy (癲癇), paralysis (癱瘓),Spinal cord-paresis,Eye -lose sight or vision disorder,Peritoneum(腹膜)-abdominal pain , diarrhea, blood-stood, enlarging liver,Lungsymptom,Brain-spinal cords patient,Peritoneum,Subcutaneous,Diagnosis,Make sure whether the patient

8、has the habit of eating the raw crab,1. Examination,Use the water sedimentation method to find the egg in the feces,Use the direct smear method to find the egg in the sputum,2. X-ray ,CT for the pleura and brain-spinal cords patient,3.Immuniology examination,For the ectopic parasitism,Method: AST,EL

9、ISA,AST-ELISA,Epidemiology,Charcteristic: parasitic zoonoses,Paragonimiasis infect the wile animal in the nature,when human being come into the area he will be infect.,Paragonimiasis had ever taken place in Japan ,Korea, Russia,Epidimiology factors:,1. Infective source:,A.Wild animal : fox, wolf, le

10、opard, cat, dog etc.,B. Human being,2. Intermediate host: The snail or the crab which grow in the small stream.,3. Infective way:,Eat the raw crab or “drunk crab” B. Eat the raw meat of transport host C. Drink the unboiling water,Treatment,Pay attention to the eating habit , not to eat the raw crab,

11、not to drink the unboiling water,2. Treat the patient: Praziquantel Albendazole Tribendimidine Artemether Artesunate,Paragonimus skrjabini,Morphology,1. Adult,Shape : Olive,Sucker: Ventral sucker is larger than oral sucker,Testes and ovary have more lobation,2. Egg: Similar to paragonimus westermuni

12、,Live cycle,Essential similar to paragonimus westermuni,The different from it is that:,1. Definitive host: fruit-eating fox (the main),Human : Abnormal host ,only young worm infect them.,2.The No.1 intermediate host: The snail which grow in the small stream,Tricula spp (擬釘螺）,Pathogenesis and clinica

13、l manifestations:,Larva migrans: some parasite invade human being , human is not the normal host, it only stay in the stage of young worm, the young worm paraste and migration in the body for a long time, at last it cause particular and peneral pathologic change.,Clinical symptom:,1.Subcutaneous type: cysts,Area: back and abdomen, four limbs, inguinal reg