基于金納米粒子的比色傳感

1、 Colorimetric Biosensing Using AuNPs ContentsColorimetric Biosensing UsingSmart Materials1Application2Conclusions3Colorimetric Biosensing Using Smart materialsvlow cost, simplicity, and practicality. does not require expensive or sophisticated instru-mentation .vapplied to field of analysis and poin

2、t-of-care diagnosisvtransforming the detection events into color changes. Common Smart materialsSmart materials graphene oxideconjugated polymerscarbon nanotubesmagnetic NPsAuNPscerium oxide NPsGold Nanoparticles (AuNPs) v Small AuNPs (e.g., 15 nm in diameter) appear red in color because the nanopar

3、ticles have an optical absorption around 520 nm due to surface plasmon resonance.When small AuNPs aggregates will make their surface plasmons combine and result in the color change from red to purple. AuNPs Aggregation vInterparticle crosslinkingvNon-crosslinking Aggregation Crosslinking Aggregation

4、 Non-crosslinking Aggregation In preparation of AuNPs, the surface-tethered capping ligands or species are often used to control AuNPs growth and to stabilize AuNPs against van der Waals attraction-induced aggregation. With respect to electrostatic stabilization, the surface charges, together with the counter ions in the medium, form a repulsive electric double layer