應(yīng)力調(diào)節(jié)對(duì)延長(zhǎng)區(qū)骨愈合影響的實(shí)驗(yàn)研究

1、檢測(cè)。結(jié)果操作檢測(cè)。結(jié)果操作結(jié)束后，兩組延長(zhǎng)區(qū)骨痂X 線片表現(xiàn)不同：對(duì)照組延長(zhǎng)區(qū) 】 牽張成骨；軸向應(yīng)力；微動(dòng)；骨延長(zhǎng)；Influenceofstressregulationon bonehealingoflengthened zone:anexperimental study Hua qing,WANGKun zheng,ZHANGMing Yu,etal.Departmentof Orthopedics, the Second Hospital, Xian Jiaotong University, Xian 710004, ChinaAbstract：ObjectiveTo explore

2、 the effects of axial stress regulation on healing of lengthened callus.MethodTibiaes of 40 rabbits dividedo2groupswerelengthened with circular external fixator.X ray bone density and histology tests were performed.ResultThe X-ray showed lengthened callus was different after operation.hecontrol grou

3、p,lengthened center had a serial callus and cortex had not formed,heexperimental group lengthened center had serial cortex and ttransfixial medullaryexpects serial Axial stress regulation and periodicity continue to shortened micromovement stress may promote healing after bone lengthening.Keywords：d

4、istractionosteogenesis； axialstress；micromovement； bone lengthening； rabbits牽張成骨(isaonooneis,D)是由lrov在提出原1緩慢牽伸組織產(chǎn)一種應(yīng)力可刺激些組織生和活躍長(zhǎng)能夠動(dòng)和促機(jī)體自身修復(fù)和生的潛能有效地療肢體等長(zhǎng)等骨科疑難病但是體大幅延長(zhǎng)后延長(zhǎng)區(qū)的愈合需很長(zhǎng)時(shí)間往往會(huì)患者帶針道的延遲合及長(zhǎng)佩帶外固定器導(dǎo)的不舒感等問(wèn)甚至導(dǎo)治療23，此，如促進(jìn)延區(qū)骨愈合是臨迫切需解決骨延區(qū)的骨是一種特類型的愈合外施加的牽變了延區(qū)的微合的進(jìn)成骨方式力負(fù)荷骨骼的構(gòu)和骨量有著極重要的響4。者對(duì)應(yīng)調(diào)節(jié)在脛骨延長(zhǎng)骨愈合的作用行了實(shí)驗(yàn)

5、研究，以察其對(duì)延長(zhǎng)區(qū)愈合的用。節(jié),運(yùn)用X 線檢查、光鏡觀察等【摘要】 1.2 1.2.1 3%戊巴比妥鈉(1mL/kg,iv)麻醉,左下肢去毛,下20mm 1.2 1.2.1 3%戊巴比妥鈉(1mL/kg,iv)麻醉,左下肢去毛,下20mm1.2mm克氏針 2枚克氏針相交角度(4050),230mm11mm4105u16萬(wàn)u1.2.3 術(shù)后觀察 所有動(dòng)物術(shù)后分籠飼養(yǎng),34105U8開(kāi)始延長(zhǎng),1mm(2次完成,0.5mm)20mm20mm4d24mm （1）X線片 在延長(zhǎng)結(jié)束時(shí)及處死動(dòng)物后分別做X（2）骨密度測(cè)定 處死動(dòng)物后)2（3）,5mm厚的薄片 1.3 SPSS8.0t2 結(jié) 果2.1 )

6、 ) 2.2 X 好 2)2.3 2.4 排 2.4 排1 對(duì)照組延長(zhǎng)段骨痂X線片 圖2 實(shí)驗(yàn)組延長(zhǎng)段骨痂X3 痂組織(2.54) 4 實(shí)驗(yàn)組延長(zhǎng)段骨痂組織3 討 論牽張成骨(distractionosteogenesis,DO)是刺激骨形成的一種獨(dú)特方法，它使肢體延長(zhǎng)技 / 1cm后,3d2mm,的原遞增 加壓。由于延長(zhǎng)長(zhǎng)度儲(chǔ)備有限(35mm左右),作用持續(xù)時(shí)間不長(zhǎng)，如何使短縮加壓發(fā)揮20mm后繼續(xù)延長(zhǎng)4mm作為儲(chǔ)備, 此后10行牽拉壓縮調(diào)節(jié)各2次, 調(diào)節(jié)幅度 1IlizarovGAthesyresseffectonesisandgrowthes.partinfluenceofstabili

7、tyoftherateandfrequenceofdistractionfixationandsoft presser vationJ.ClinOrthop1989,239:263-e2KocaogluM,EralpL,SenC,etal.Managementofstiffhypertrophicnonunionsdistractionosteogenesis:areportof16casesJ.JOrthopTrauma2003,8:543-3AntociV,OnoCM,AntociVJr,etal.Bonelengtheninginchildren:howtopredictcomplica

8、tionsrateandcomplexityJ.JPediatrOrthop2006,5:634-, , 5IlizarovGA.Transosseousosteosynthesis theoreticalandclinicalaspectsregenerationandgrowthofeJ.Berlin:Springer Verlag,1992,137-6KocaogluM,EralpL,SenC,etal.Managementofstiffhypertrophicnonunionsdistractionosteogenesis:ataleof16casesJ.JOrthopTrauma,2

9、003,17:543-7RheeST,anSR.Pediatricmandibulardistractionosteogenesis:theandthefutureJ.JCraniofacSurg,2003,14:803-8周 強(qiáng)，等. 脛骨截骨延長(zhǎng)治療雙小腿不等長(zhǎng)及身材矮小J.，,李 剛，等. 脛骨截骨延長(zhǎng)治療雙小腿不等長(zhǎng)及身材矮小J.，,李 剛13HamanishiC,YoshiT,TotaniY,etal.Lengthenedivatedbyshortening.Histologicalandcytomorph 14ColeJD,JustinD,KasparisT,etramedulla

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