Ophiopogonin-D-Standard-生命科學試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEOphiopogoninD(Standard)Cat.No.:HY-N0515RCASNo.:945619-74-9分子式:C??H??O??分子量:855.02作用靶點:PPAR;PPAR;NF-κB;NF-κB;CalciumChannel;CalciumChannel作用通路:CellCycle/DNADamage;MetabolicEnzyme/Protease;VitaminDRelated/NuclearReceptor;NF-κB;MembraneTransporter/IonChannel;NeuronalSignaling儲存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 OphiopogoninD(Standard)是OphiopogoninD的分析標準品。本產(chǎn)品用于研究及分析應用。OphiopogoninD是從麥冬(Ophiopogonjaponicus)的塊莖中分離的，是一種罕見的天然存在的C29甾體糖苷。OphiopogoninD是CYP2J3誘導劑，其通過增加人臍靜脈內(nèi)皮細胞(HUVECs)中CYP2J2/EETs和PPARα的表達，顯著抑制AngII誘導的IC50&Target PPARα,NF-κB,Ca2+[2]REFERENCESWangL,etal.Homo-aro-cholestane,furostaneandspirostanesaponinsfromthetubersofOphiopogonjaponicus.Phytochemistry.2017Apr;136:125-132.HuangX,etal.OphiopogoninDandEETsameliorateAngII-inducedinflammatoryresponsesviaactivatingPPARαinHUVECs.BiochemBiophysResCommun.2017Aug19;490(2):123-133.WangL,etal.Homo-aro-cholestane,furostaneandspirostanesaponinsfromthetubersofOphiopogonjaponicus.Phytochemistry.2017Apr;136:125-132.HuangX,etal.OphiopogoninDandEETsameliorateAngII-inducedinflammatoryresponsesviaactivatingPPARαinHUVECs.BiochemBiophysResCommun.2017Aug19;490(2):123-133.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax