Tanaproget-NSP-989-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETanaprogetCat. No.: HY-15606CAS No.: 304853-42-7Synonyms: NSP-989分式: CHNOS分量: 297.37作靶點(diǎn): Progesterone Receptor作通路: Others儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 50 mg/mL (168.14 mM)

2、H2O : 90% corn oilSolubility: 2.5 mg/mL (8.41 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 Tanaproget (NSP-989)新型甾體孕酮受體激動(dòng)劑。戶(hù)使本產(chǎn)品發(fā)表的科研獻(xiàn) bioRxiv. 2019 Aug.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Bruner-Tran KL, et al. Down-reg

3、ulation of endometrial matrix metalloproteinase-3 and -7 expression in vitro and therapeutic regressionof experimental endometriosis in vivo by a novel nonsteroidal progesterone receptor agonist, tanaproget. J Clin Endocrinol Metab. 2006Apr;91(4):1554-60.2. Zhang Z, et al. Molecular and pharmacologi

4、cal properties of a potent and selective novel nonsteroidal progesterone receptor agonisttanaproget. J Biol Chem. 2005 Aug 5;280(31):28468-75.3. Bapst JL, et al. Pharmacokinetics and safety of tanaproget, a nonsteroidal progesterone receptor agonist, in healthy women.Contraception. 2006 Nov;74(5):414-8.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: